All Outputs (41)

Establishment of a novel set of vectors for transformation of the dinoflagellate Amphidinium carterae (2022)
Working Paper

Peridinin-containing dinoflagellate algae have a chloroplast genome formed from plasmid-like minicircles. This fragmented genome has allowed us to develop a genetic modification methodology involving the use of biolistics to introduce artificial mini... Read More about Establishment of a novel set of vectors for transformation of the dinoflagellate Amphidinium carterae.

The effects of sleep disturbance on dyspnoea and impaired lung function following COVID-19 hospitalisation: a prospective multi-centre cohort study (2022)
Working Paper

GPT4 : The Ultimate Brain (2022)
Working Paper

We introduce a powerful general probabilistic theory, GPT4, that extends classical and quantum theories to include higher-dimensional probabilistic models. GPT4 results from the four-fold integration of GPT in physics (Generalized Probabilistic T... Read More about GPT4 : The Ultimate Brain.

The protective role of staff wellbeing centres for wellbeing and presenteeism in healthcare workers during the COVID-19 pandemic: Secondary analysis of COVID-Well data (2022)
Working Paper

Background Supported wellbeing centres established during the COVID-19 pandemic provided high quality rest spaces and access to peer-to-peer psychological first aid for healthcare workers (HCWs). The centres were well accessed and valued by HCWs,... Read More about The protective role of staff wellbeing centres for wellbeing and presenteeism in healthcare workers during the COVID-19 pandemic: Secondary analysis of COVID-Well data.

Modified bronchoscopy masks mitigate aerosols during gastroscopies (2022)
Working Paper

Digestive endoscopy has been proven to produce aerosols (1–3). This represents a risk of infection by COVID-19 and other airborne viruses. A number of protective barriers have been proposed to minimise that risk. Continuous suction of the oral cavity... Read More about Modified bronchoscopy masks mitigate aerosols during gastroscopies.

Assessing diversity and inclusivity is the next frontier in mental health recovery narrative research and practice (Preprint) (2022)
Working Paper

Demand for digital health interventions is increasing in many countries. The use of recorded mental health recovery narratives in digital health interventions is becoming more widespread in clinical practice. Mental health recovery narratives are fir... Read More about Assessing diversity and inclusivity is the next frontier in mental health recovery narrative research and practice (Preprint).

Solutions to Hazardous Wastes Issues in the Leather Industry: Adsorption of Chromium Iii and Vi from Leather Industry Wastewaters Using Activated Carbons Produced from Leather Industry Solid Wastes (2022)
Working Paper

This study presents the use of an innovative material to tackle hazardous wastes in the leather industry. Activated carbons produced from Leather industry waste (LIW) were used to adsorb Chromium (Cr) III and (VI), which are found in leather wastewa... Read More about Solutions to Hazardous Wastes Issues in the Leather Industry: Adsorption of Chromium Iii and Vi from Leather Industry Wastewaters Using Activated Carbons Produced from Leather Industry Solid Wastes.

Feasibility and Acceptability of an Internet of Things–Enabled Sedentary Behavior Intervention: Mixed Methods Study (Preprint) (2022)
Working Paper

Background: Encouraging office workers to break up prolonged sedentary behavior (SB) at work with regular micro-breaks can be beneficial yet challenging. Internet of Things (IoT) offers great promise for delivering more subtle and hence acceptable b... Read More about Feasibility and Acceptability of an Internet of Things–Enabled Sedentary Behavior Intervention: Mixed Methods Study (Preprint).

Morphology-density Relation, Quenching, and Mergers in CARLA Clusters and Proto-Clusters at 1.4 < z < 2.8 (2022)
Working Paper

On the origins of phenotypic parallelism in benthic and limnetic stickleback (2022)
Working Paper

Rapid evolution of similar phenotypes in similar environments, giving rise to in situ parallel adaptation, is an important hallmark of ecological speciation. However, what appears to be in situ adaptation can also arise by dispersal of divergent line... Read More about On the origins of phenotypic parallelism in benthic and limnetic stickleback.

‘It Means We are Not Safe’: Understanding and Learning from Household Experiences of Water Scarcity, Flood and Fire in Marginalized Settlements in the Cape Flats, South Africa (2022)
Working Paper

As climate change-related extreme weather events such as flooding and droughts increase in frequency and severity in most cities worldwide, there is a need to deepen understanding of disaster risks and adaptive capacities. A significant percentage of... Read More about ‘It Means We are Not Safe’: Understanding and Learning from Household Experiences of Water Scarcity, Flood and Fire in Marginalized Settlements in the Cape Flats, South Africa.

Design, Construction, and Functional Characterization of a tRNA Neochromosome in Yeast (2022)
Working Paper

Here we report the design, construction and characterization of a tRNA neochromosome, a designer chromosome that functions as an additional, de novo counterpart to the native complement of Saccharomyces cerevisiae. Intending to address one of the cen... Read More about Design, Construction, and Functional Characterization of a tRNA Neochromosome in Yeast.

Just Transition: Pathways to Socially Inclusive Decarbonisation (2022)
Working Paper

Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees During the COVID-19 Pandemic (2022)
Working Paper

Background: HIV poses a threat to global health. With effective treatment options available, education and testing strategies are essential in preventing transmission. Text messaging is an effective tool for health promotion and can be used to target... Read More about Test@Work Texts: Mobile Phone Messaging to Increase Awareness of HIV and HIV Testing in UK Construction Employees During the COVID-19 Pandemic.

Fade in, fade out: Do shifts in visual perspective predict the consistency of real-world memories? (2022)
Working Paper

Memories of our personal past are not exact accounts of what occurred. Instead, memory reconstructs the past in adaptive–though not always faithful–ways. Using a naturalistic design, here we asked how the visual perspective adopted in the mind’s eye... Read More about Fade in, fade out: Do shifts in visual perspective predict the consistency of real-world memories?.

Organoruthenium Complexes Containing Hemilabile Phosphinodicarboxamide Ligands (2022)
Working Paper

Ruthenium complexes of hemilabile phosphinocarboxamide ligands, and their use to form metallacycles using halide abstraction/deprotonation reactions are reported. Thus, [Ru(p-cym){PPh2C(=O)NHR}Cl2; R = iPr (1), Ph (2), p-tol (3)] and [Ru(p-cym){PPh2C... Read More about Organoruthenium Complexes Containing Hemilabile Phosphinodicarboxamide Ligands.

Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection (2022)
Working Paper

Background Chronic sputum production impacts on quality of life and is a feature of many respiratory diseases. Identification of the genetic variants associated with chronic sputum production in a disease agnostic sample could improve understanding o... Read More about Genome-wide association study of chronic sputum production implicates loci involved in mucus production and infection.

Enhancement of Syngas Production in Co-Pyro-Gasification of Biomass and Plastic Waste Materials: Computational Study (2022)
Working Paper

The process of co-pyro-gasification of biomass and plastics appears to have the potential for increasing syngas production for power generation and thus minimizing the impact of plastic waste on the environment. This study was based on co-pyro-gasifi... Read More about Enhancement of Syngas Production in Co-Pyro-Gasification of Biomass and Plastic Waste Materials: Computational Study.

Undirected, Pd-catalysed deuteration of indoles with programmable regioselectivity (2022)
Working Paper

Methods for selective deuterium-incorporation into drug-like molecules have become extremely valuable due to the commercial and biological importance of deuterated compounds. Selective C2-deuteration of indoles currently requires the installation of... Read More about Undirected, Pd-catalysed deuteration of indoles with programmable regioselectivity.

Synthetic yeast chromosome XI design enables extrachromosomal circular DNA formation on demand (2022)
Working Paper

We describe construction of the 660 kilobase synthetic yeast chromosome XI (synXI) and reveal how synthetic redesign of non-coding DNA elements impact the cell. To aid construction from synthesized 5 to 10 kilobase DNA fragments, we implemented CRISP... Read More about Synthetic yeast chromosome XI design enables extrachromosomal circular DNA formation on demand.