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Hit-to-Lead Optimization of the Natural Product Oridonin as Novel NLRP3 Inflammasome Inhibitors with Potent Anti-Inflammation Activity (2024)
Journal Article

Targeting NLRP3 inflammasome with inhibitors is a novel strategy for NLRP3-driven diseases. Herein, hit compound 5 possessing an attractive skeleton was identified from our in-house database of oridonin, and then a potential lead compound 32 was obta... Read More about Hit-to-Lead Optimization of the Natural Product Oridonin as Novel NLRP3 Inflammasome Inhibitors with Potent Anti-Inflammation Activity.

Risk factors for the development of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis, following drug administration: a systematic review and meta-analysis (2024)
Journal Article

The aim of this systematic review was to determine risk factors for the development of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis (SJS/TEN), following drug administration. The study protocol was registered on PROSPERO. The Preferred Reportin... Read More about Risk factors for the development of Stevens-Johnson Syndrome/Toxic Epidermal Necrolysis, following drug administration: a systematic review and meta-analysis.

Are vehicle lifespan caps an effective and efficient method for reducing US light-duty vehicle fleet GHG emissions? (2024)
Journal Article

With light duty vehicles (LDVs) responsible for 17% of annual US greenhouse gas (GHG) emissions, integrating emerging GHG-reducing technologies into the fleet is essential. However, the slow rate of vehicle turnover presents a significant barrier to... Read More about Are vehicle lifespan caps an effective and efficient method for reducing US light-duty vehicle fleet GHG emissions?.

Thermodynamic Modeling and Performance Analysis of Photovoltaic-Thermal Collectors Integrated with Phase Change Materials: Comprehensive Energy and Exergy Analysis (2024)
Journal Article

Phase change materials (PCMs) integrated with photovoltaic-thermal (PVT) collectors can simultaneously generate and store electrical and thermal energy. However, design optimization requires accurate modeling of the complex heat transfer processes in... Read More about Thermodynamic Modeling and Performance Analysis of Photovoltaic-Thermal Collectors Integrated with Phase Change Materials: Comprehensive Energy and Exergy Analysis.

Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol (2024)
Journal Article

Telerehabilitation (TR) shows promise as a method of remote service delivery, yet there is little guidance to inform implementation in the context of the National Health Service (NHS) in England. This paper presents the protocol for a realist synthes... Read More about Investigating the Implementation of Community-Based Stroke Telerehabilitation in England; A Realist Synthesis Study Protocol.

Terrestrial bodies (2024)
Journal Article

As socio-ecological crises deepen, it is increasingly important that analyses of territory consider the other-than-human. Through a detailed engagement with a range of territorial currents, Gonin et al. do just this, introducing the idea of ‘terrestr... Read More about Terrestrial bodies.

Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents (2024)
Journal Article

The first case of CWD in a Norwegian red deer was detected by a routine ELISA test and confirmed by western blotting and immunohistochemistry in the brain stem of the animal. Two different western blotting tests were conducted independently in two di... Read More about Classical BSE dismissed as the cause of CWD in Norwegian red deer despite strain similarities between both prion agents.

On wounds, incompleteness, and conviviality: Notes on counter-actualising the conditions of the contemporary (2024)
Journal Article

For Bernard Stiegler ‘the question of philosophy is first of all that of action’ (p.7). By extending this statement to philosophy of education, I consider the possibilities of action in education in responding to the conditions of the contemporary. T... Read More about On wounds, incompleteness, and conviviality: Notes on counter-actualising the conditions of the contemporary.

Mental health workers’ perspectives on the implementation of a peer support intervention in five countries: qualitative findings from the UPSIDES study (2024)
Journal Article

Objective: The introduction of peer support in mental health teams creates opportunities and challenges for both peer and non-peer staff. However, the majority of research on mental health workers’ (MHWs) experiences with peer support comes from high... Read More about Mental health workers’ perspectives on the implementation of a peer support intervention in five countries: qualitative findings from the UPSIDES study.

Mitigating the bullwhip effect through supply chain ESG transparency: roles of digitalization and signal strength (2024)
Journal Article

Purpose-The call for supply chain transparency (SCT), especially the Environmental, social, and governance (ESG) aspect, is getting increasingly louder. Based on the signaling theory, our study investigates the operational benefit of supply chain tra... Read More about Mitigating the bullwhip effect through supply chain ESG transparency: roles of digitalization and signal strength.

Zero-valent iron (ZVI) facilitated in-situ selenium (Se) immobilization and its recovery by magnetic separation: Mechanisms and implications for microbial ecology (2024)
Journal Article

Selenium (Se(VI)) is environmentally toxic. One of the most popular reducing agents for Se(VI) remediation is zero-valent iron (ZVI). However, most ZVI studies were carried out in water matrices, and the recovery of reduced Se has not been investigat... Read More about Zero-valent iron (ZVI) facilitated in-situ selenium (Se) immobilization and its recovery by magnetic separation: Mechanisms and implications for microbial ecology.