Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids
(2024)
Journal Article
Morgan, D., Lam, H. W., & Guiry, P. (in press). Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids. European Journal of Organic Chemistry, https://doi.org/10.1002/ejoc.202400445
Herein we report the first syn‐arylnickelative cyclisation with ketone‐ and imine‐tethered terminal alkynes (16 examples) in yields of up to 89%. The reaction proceeds via a syn‐aryl nickelation of a terminal alkyne followed by cyclisation of the res... Read More about Nickel‐Catalysed syn‐Selective Arylnickelation and Cyclisation of Ketone/Imine‐Tethered Terminal Alkynes with Arylboronic Acids.