Rhodium-catalyzed arylative cyclization of alkynyl malonates by 1,4-rhodium(I) migration
O'Brien, Luke; Karad, Somnath Narayan; Lewis, William; Lam, Hon Wai
Somnath Narayan Karad
Hon Wai Lam
The synthesis of functionalized 1-tetralones by the rhodium(I)-catalyzed reaction of alkynyl malonates with arylboronic acids is described. These arylative cyclizations proceed via an alkenyl-to-aryl 1,4-Rh(I) migration as a key step. Preliminary results of an enantioselective variant of these reactions are also presented.
|Journal Article Type||Article|
|Publication Date||Sep 28, 2019|
|Publisher||Royal Society of Chemistry|
|Peer Reviewed||Peer Reviewed|
|APA6 Citation||O'Brien, L., Karad, S. N., Lewis, W., & Lam, H. W. (2019). Rhodium-catalyzed arylative cyclization of alkynyl malonates by 1,4-rhodium(I) migration. Chemical Communications, 55(76), 11366-11369. https://doi.org/10.1039/c9cc05205d|
|Keywords||Materials chemistry; Electronic, optical and magnetic materials; General chemistry; Surfaces, Coatings and films; Metals and alloys; Ceramics and composites; Catalysis|
This file is under embargo until Aug 27, 2020 due to copyright restrictions.
You might also like
Nickel-catalyzed, ligand-free, diastereoselective synthesis of 3-methyleneindan-1-ols
Restricting shuttling in bis(imidazolium)…pillararene rotaxanes using metal coordination