All Outputs (1157)

Optimized immobilization of lectins using self-assembled monolayers on polysilicon encoded materials for cell tagging (2013)
Journal Article

Self-assembled monolayers (SAMs) have been used for the preparation of functional microtools consisting of encoded polysilicon barcodes biofunctionalized with proteins of the lectin family. These hybrid microtools exploit the lectins ability for reco... Read More about Optimized immobilization of lectins using self-assembled monolayers on polysilicon encoded materials for cell tagging.

Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1? (2013)
Journal Article

Introduction: Arthritic diseases are characterized by the degradation of collagenous and noncollagenous extracellular matrix (ECM) components in articular cartilage. The increased expression and activity of matrix metalloproteinases (MMPs) is partly... Read More about Carprofen inhibits the release of matrix metalloproteinases 1, 3, and 13 in the secretome of an explant model of articular cartilage stimulated with interleukin 1?.

UK medical teaching about ageing is improving but there is still work to be done: the Second National Survey of Undergraduate Teaching in Ageing and Geriatric Medicine (2013)
Journal Article

Introduction: in 2008, a UK national survey of undergraduate teaching about ageing and geriatric medicine identified deficiencies, including failure to adequately teach about elder abuse, pressure ulcers and bio- and social gerontology. We repeated t... Read More about UK medical teaching about ageing is improving but there is still work to be done: the Second National Survey of Undergraduate Teaching in Ageing and Geriatric Medicine.

Financial liberalization and the relationship-specificity of exports (2013)
Journal Article

We investigate the causal impact of equity market liberalizations on sectoral export performance across 91 countries (1980–1997). The increased availability of external finance has boosted trade of industries that intensively use relationship-specifi... Read More about Financial liberalization and the relationship-specificity of exports.

Composition and properties of the surface of oil bodies recovered from Echium Plantagineum (2013)
Journal Article

Neutral-lipids within oilseeds are most commonly stored in oil bodies, small spherical organelles with oleosin proteins inserted through a phospholipid monolayer. Oil bodies extracted from Echium plantagineum are highly enriched in polyunsaturated fa... Read More about Composition and properties of the surface of oil bodies recovered from Echium Plantagineum.

Smc5/6 Coordinates Formation and Resolution of Joint Molecules with Chromosome Morphology to Ensure Meiotic Divisions (2013)
Journal Article

During meiosis, Structural Maintenance of Chromosome (SMC) complexes underpin two fundamental features of meiosis: homologous recombination and chromosome segregation. While meiotic functions of the cohesin and condensin complexes have been delineate... Read More about Smc5/6 Coordinates Formation and Resolution of Joint Molecules with Chromosome Morphology to Ensure Meiotic Divisions.

Gold-catalyzed oxidative coupling of arylsilanes and arenes: Origin of selectivity and improved precatalyst (2013)
Journal Article

The mechanism of gold-catalyzed coupling of arenes with aryltrimethylsilanes has been investigated, employing an improved precatalyst (thtAuBr3) to facilitate kinetic analysis. In combination with linear free-energy relationships, kinetic isotope eff... Read More about Gold-catalyzed oxidative coupling of arylsilanes and arenes: Origin of selectivity and improved precatalyst.

Engaging with energy reduction: Does a climate change frame have the potential for achieving broader sustainable behaviour? (2013)
Journal Article

Reducing energy use is key in meeting ambitious climate change targets being set around the world. This research considers the psychological impact, and potential for behavioural spillover, resulting from receiving energy information framed in terms... Read More about Engaging with energy reduction: Does a climate change frame have the potential for achieving broader sustainable behaviour?.

China's military operations other than war (2013)
Journal Article

Although political friction and ideological differences between China and the West can hamper co-operation on missions known as ‘Military Operations Other than War’, the UK and China have achieved a certain level of success in this regard, particular... Read More about China's military operations other than war.

A depth-averaged model for non-isothermal thin-film rimming flow (2013)
Journal Article

A model for non-isothermal shear-driven thin-film flow on the inside surface of a stationary circular cylinder is presented. Motivated by an application to film flow in an aero-engine bearing chamber the model extends lubrication theory analysis of t... Read More about A depth-averaged model for non-isothermal thin-film rimming flow.

Stochastic service network design with rerouting (2013)
Journal Article

Service network design under uncertainty is fundamentally crucial for all freight transportation companies. The main challenge is to strike a balance between two conflicting objectives: low network setup costs and low expected operational costs. Toge... Read More about Stochastic service network design with rerouting.

Support for the integration of green roof constructions within Chinese building energy performance policies (2013)
Journal Article

Green roofs could act as a thermal buffer in buildings and offer potential energy savings. However, the energy benefits from green roofs are not usually properly recognised by traditional building energy regulations. Building energy regulations are t... Read More about Support for the integration of green roof constructions within Chinese building energy performance policies.

Knowledge, sources of information, and risk factors for sexually transmitted infections among secondary school youth in Zaria, Northern Nigeria (2013)
Journal Article

Background: Sexually transmitted infections (STIs) are responsible for a variety of health problems especially among the youth who engage in risky sexual behavior. There are few studies that describe STIs among the youths in Northern Nigeria. The obj... Read More about Knowledge, sources of information, and risk factors for sexually transmitted infections among secondary school youth in Zaria, Northern Nigeria.

Strain-mediated coupling in a quantum dot-mechanical oscillator hybrid system (2013)
Journal Article

Recent progress in nanotechnology has allowed the fabrication of new hybrid systems in which a single two-level system is coupled to a mechanical nanoresonator. In such systems the quantum nature of a macroscopic degree of freedom can be revealed and... Read More about Strain-mediated coupling in a quantum dot-mechanical oscillator hybrid system.

Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach (2013)
Journal Article

Malaria is an infectious disease caused by parasites of the genus Plasmodium, which leads to approximately one million deaths per annum worldwide. Chemical validation of new antimalarial targets is urgently required in view of rising resistance to cu... Read More about Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach.

A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development (2013)
Journal Article

The phytohormone auxin is a key developmental signal in plants. So far, only auxin perception has been described to trigger the release of transcription factors termed AUXIN RESPONSE FACTORs (ARFs) from their AUXIN/INDOLE-3-ACETIC ACID (AUX/IAA) repr... Read More about A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development.

Challenges with the implementation of an Integrated Disease Surveillance and Response (IDSR) system: systematic review of the lessons learned (2013)
Journal Article

Introduction: Despite a realistic strategy and availability of resources, multiple challenges still overwhelm countries grappling with the challenges of communicable disease surveillance. The Integrated Disease Surveillance and Response (IDSR) strate... Read More about Challenges with the implementation of an Integrated Disease Surveillance and Response (IDSR) system: systematic review of the lessons learned.

Exposure of neonatal rats to maternal cafeteria feeding during suckling alters hepatic gene expression and DNA methylation in the insulin signalling pathway (2013)
Journal Article

Nutrition in early life is a determinant of lifelong physiological and metabolic function. Diseases that are associated with ageing may, therefore, have their antecedents in maternal nutrition during pregnancy and lactation. Rat mothers were fed eith... Read More about Exposure of neonatal rats to maternal cafeteria feeding during suckling alters hepatic gene expression and DNA methylation in the insulin signalling pathway.

Poly(Acrylic Acid)–Poly(Ethylene Glycol) Nanoparticles Designed for Ophthalmic Drug Delivery (2013)
Journal Article

Poly(acrylic acid) (PAA) and poly(ethylene glycol) (PEG), four-arm, amine-terminated particles with nanometer size and spherical shape were obtained by the polymers cross-linking, via activation with 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide hy... Read More about Poly(Acrylic Acid)–Poly(Ethylene Glycol) Nanoparticles Designed for Ophthalmic Drug Delivery.

People with dementia and carers’ experiences of dementia care and services: Outcomes of a focus group study (2013)
Journal Article

© 2013, The Author(s) 2013. An ageing population and an associated increase in the prevalence of dementia are of increasing concern in the United Kingdom and worldwide. Recently, the United Kingdom and other European countries implemented national de... Read More about People with dementia and carers’ experiences of dementia care and services: Outcomes of a focus group study.