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All Outputs (194)

Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the developing male Wistar(Han) rat II: chronic dosing causes developmental delay (2007)
Journal Article

We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure continuous exposure of the fetus. 5-6 week old rats were exp... Read More about Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the developing male Wistar(Han) rat II: chronic dosing causes developmental delay.

Amphetamine and the adenosine A2A antagonist KW-6002 enhance the effects of conditional temporal probability of a stimulus in rats (2007)
Journal Article

As the length of foreperiod preceding an imperative signal increases, reaction time decreases and anticipatory (prior to the signal) responding increases. The authors designed a task to dissociate the effect of elapsing time in the foreperiod and con... Read More about Amphetamine and the adenosine A2A antagonist KW-6002 enhance the effects of conditional temporal probability of a stimulus in rats.

The streptavidin/biotinylated DNA/protein bound complex protocol for determining the association of c-JUN protein with NANOG promoter (2007)
Journal Article

Chromatin immunoprecipitation (ChIP) is a widely used and pre-eminent technique for detecting the association of an individual protein or a particular protein complex with its specific DNA sequence(s) in vivo. Herein we introduce a novel and simple b... Read More about The streptavidin/biotinylated DNA/protein bound complex protocol for determining the association of c-JUN protein with NANOG promoter.

Characterization of an enhancer region of the galanin gene that directs expression to the dorsal root ganglion and confers responsiveness to axotomy (2007)
Journal Article

Galanin expression markedly increases in the dorsal root ganglion (DRG) after sciatic nerve axotomy and modulates pain behavior and regeneration of sensory neurons. Here, we describe transgenic mice expressing constructs with varying amounts of seque... Read More about Characterization of an enhancer region of the galanin gene that directs expression to the dorsal root ganglion and confers responsiveness to axotomy.

Effect of maternal dietary restriction during pregnancy on lamb carcass characteristics and muscle fiber composition (2007)
Journal Article

Two experiments were conducted to determine whether the decreased proportion of fast muscle fibers seen previously in 2-wk-old lambs from ewes that were dietary restricted from d 30 to 70 of gestation are still evident in older lambs and what the con... Read More about Effect of maternal dietary restriction during pregnancy on lamb carcass characteristics and muscle fiber composition.

Critical Psychiatry (2007)
Journal Article

Critical psychiatry appraises and comments upon psychiatric services as they are usually provided. This article, prompted by the publication of a recent book, considers the place of critical psychiatry historically and in the context of contemporar... Read More about Critical Psychiatry.

National evaluation of NHS genetics service investments: emerging issues from the cancer genetics pilots (2007)
Journal Article

In seeking to fulfil the ambition of the 2003 genetics white paper, Our Inheritance, Our Future, to ‘mainstream’ genetic knowledge and practices, the Department of Health provided start-up funding for pilot services in various clinical areas, includi... Read More about National evaluation of NHS genetics service investments: emerging issues from the cancer genetics pilots.

A Utilitarian Perspective of Social and Medical Contributions to Three Illustrative Conditions, and Recent UK NHS Policy Initiatives (2007)
Journal Article

Background: To date debate concerning the relative merits of social and medical sciences has been largely academic. Aims: To outline and critically appraise a utilitarian approach to mental health research that reflects a critical realist perspect... Read More about A Utilitarian Perspective of Social and Medical Contributions to Three Illustrative Conditions, and Recent UK NHS Policy Initiatives.