All Outputs (119)

Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders (2019)
Journal Article
Galieva, L. R., James, V., Mukhamedshina, Y. O., & Rizvanov, A. A. (2019). Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders. Frontiers in Neuroscience, 13, Article 163. https://doi.org/10.3389/fnins.2019.00163

The use of extracellular vesicles (EVs) as cell free therapy is a promising approach to stimulate tissue regeneration including that of the nervous system. EVs transfer bioactive proteins and lipids, RNA and microRNAs, which play a relevant role in E... Read More about Therapeutic Potential of Extracellular Vesicles for the Treatment of Nerve Disorders.

Development and validation of a new standardised data collection tool to aid in the diagnosis of canine skin allergies (2019)
Journal Article
Harvey, N. D., Shaw, S. C., Blott, S. C., Vàzquez-Diosdado, J. A., & England, G. C. W. (2019). Development and validation of a new standardised data collection tool to aid in the diagnosis of canine skin allergies. Scientific Reports, 9, Article 3039. https://doi.org/10.1038/s41598-019-39630-3

Canine atopic dermatitis (cAD) is a common hereditary clinical syndrome in domestic dogs with no definitive diagnostic tests, which causes marked morbidity and has a high economic impact internationally. We created a novel questionnaire for Labrador... Read More about Development and validation of a new standardised data collection tool to aid in the diagnosis of canine skin allergies.

Anatomy and pathology of the Texel sheep larynx (2019)
Journal Article
Waine, K., Strugnell, B., Remnant, J., Lovatt, F., Green, M., Rideout, H., Genever, E., & Baiker, K. (2019). Anatomy and pathology of the Texel sheep larynx. Veterinary Sciences, 6(1), Article 21. https://doi.org/10.3390/vetsci6010021

Laryngeal chondritis, or “Texel throat”, is a disease affecting the upper respiratory tract of sheep with breeds like the Texel appearing to be predisposed. Previous work suggests the conformation of these breeds of sheep may be predisposing these an... Read More about Anatomy and pathology of the Texel sheep larynx.

BSE infectivity survives burial for five years with only limited spread (2019)
Journal Article
Somerville, R. A., Fernie, K., Smith, A., Bishop, K., Maddison, B. C., Gough, K. C., Id, *., Hunter, N., & Gough, K. C. (2019). BSE infectivity survives burial for five years with only limited spread. Archives of Virology, 164(4), 1135–1145. https://doi.org/10.1007/s00705-019-04154-8

© 2019, The Author(s). The carcasses of animals infected with bovine spongiform encephalopathy (BSE), scrapie or chronic wasting disease (CWD) that remain in the environment (exposed or buried) may continue to act as reservoirs of infectivity. We co... Read More about BSE infectivity survives burial for five years with only limited spread.

DirtyGenes: testing for significant changes in gene or bacterial population compositions from a small number of samples (2019)
Journal Article
Shaw, L. M., Blanchard, A., Chen, Q., An, X., Davies, P., Totemeyer, S., Zhu, Y.-G., & Stekel, D. J. (2019). DirtyGenes: testing for significant changes in gene or bacterial population compositions from a small number of samples. Scientific Reports, 9, Article 2373. https://doi.org/10.1038/s41598-019-38873-4

High throughput genomics technologies are applied widely to microbiomes in humans, animals, soil and water, to detect changes in bacterial communities or the genes they carry, between different environments or treatments. We describe a method to test... Read More about DirtyGenes: testing for significant changes in gene or bacterial population compositions from a small number of samples.

Topics discussed, examinations performed and strategies implemented during canine and feline booster vaccination consultations (2019)
Journal Article
Robinson, N. J., Belshaw, Z., Brennan, M. L., & Dean, R. S. (2019). Topics discussed, examinations performed and strategies implemented during canine and feline booster vaccination consultations. Veterinary Record, 184(8), Article 252. https://doi.org/10.1136/vr.104835

© British Veterinary Association 2019. Vaccination consultations account for a large proportion of the small animal veterinary caseload. The aim of this study was to determine the content of canine and feline booster vaccination consultations and gat... Read More about Topics discussed, examinations performed and strategies implemented during canine and feline booster vaccination consultations.

Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment (2019)
Journal Article
Al-Mayahy, M. H., Sabri, A. H., Rutland, C. S., Holmes, A., McKenna, J., Marlow, M., & Scurr, D. J. (2019). Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment. European Journal of Pharmaceutics and Biopharmaceutics, 139, 33-43. https://doi.org/10.1016/j.ejpb.2019.02.006

Basal cell carcinoma (BCC) is the most common skin cancer in humans. Topical treatment with imiquimod provides a non-invasive, self-administered treatment with relatively low treatment cost. Despite displaying excellent efficacy, imiquimod is only li... Read More about Insight into imiquimod skin permeation and increased delivery using microneedle pre-treatment.

Mitochondrial respiratory states and rates (2019)
Other
Gnaiger, E., & Chakrabarti, L. (2019). Mitochondrial respiratory states and rates

As the knowledge base and importance of mitochondrial physiology to human health expands, the necessity for harmonizing the terminology concerning mitochondrial respiratory states and rates has become increasingly apparent. The chemiosmotic theory es... Read More about Mitochondrial respiratory states and rates.

Prevalence of feline lungworm Aelurostrongylus abstrusus in England (2019)
Journal Article
Elsheikha, H. M., Wright, I., Wang, B., & Schaper, R. (2019). Prevalence of feline lungworm Aelurostrongylus abstrusus in England. Veterinary parasitology (Amsterdam), 16, 100271. https://doi.org/10.1016/j.vprsr.2019.100271

Infection of cats with lungworm Aelurostrongylus abstrusus has recentlbeen documented in the UK. Here, we aimed to study the prevalence of A. abstrusus in fecal samples from cats across England. A total of 950 fecal samples were collected from cats t... Read More about Prevalence of feline lungworm Aelurostrongylus abstrusus in England.

Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy (2019)
Journal Article
Mahdmina, A., Evans, A., Yates, D., & White, K. L. (2019). Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy. Journal of Feline Medicine and Surgery, https://doi.org/10.1177/1098612x19826357

Objectives

The aim of this study was to compare quality of anaesthesia and analgesia between methadone and buprenorphine in combination with medetomidine after induction with intramuscular (IM) alfaxalone in cats undergoing ovariohysterectomy.... Read More about Comparison of the effects of buprenorphine and methadone in combination with medetomidine followed by intramuscular alfaxalone for anaesthesia of cats undergoing ovariohysterectomy.

African savanna elephants (Loxodonta africana) as an example of a herbivore making movement choices based on nutritional needs (2019)
Journal Article
Sach, F., Dierenfeld, E. S., Langley-Evans, S. C., Watts, M. J., & Yon, L. (2019). African savanna elephants (Loxodonta africana) as an example of a herbivore making movement choices based on nutritional needs. PeerJ, 7, https://doi.org/10.7717/peerj.6260

© 2019 Sach et al. Background: The increasing human population and global intensification of agriculture have had a major impact on the world’s natural ecosystems and caused devastating effects on populations of mega-herbivores such as the African sa... Read More about African savanna elephants (Loxodonta africana) as an example of a herbivore making movement choices based on nutritional needs.

A review of paratuberculosis in dairy herds — Part 1: Epidemiology (2019)
Journal Article
McAloon, C. G., Roche, S., Ritter, C., Barkema, H. W., Whyte, P., More, S. J., O’Grady, L., Green, M. J., & Doherty, M. L. (2019). A review of paratuberculosis in dairy herds — Part 1: Epidemiology. Veterinary Journal, 246, 59-65. https://doi.org/10.1016/j.tvjl.2019.01.010

Bovine paratuberculosis is a chronic infectious disease of cattle caused by Mycobacterium avium subspecies paratuberculosis (MAP). This is the first in a two-part review of the epidemiology and control of paratuberculosis in dairy herds. Paratubercul... Read More about A review of paratuberculosis in dairy herds — Part 1: Epidemiology.

A review of paratuberculosis in dairy herds — Part 2: On-farm control (2019)
Journal Article
McAloon, C. G., Roche, S., Ritter, C., Barkema, H. W., Whyte, P., More, S. J., O’Grady, L., Green, M. J., & Doherty, M. L. (2019). A review of paratuberculosis in dairy herds — Part 2: On-farm control. Veterinary Journal, 246, 54-58. https://doi.org/10.1016/j.tvjl.2019.01.009

Bovine paratuberculosis is a chronic infectious disease of cattle, caused by Mycobacterium avium subspecies paratuberculosis (MAP). This is the second in a two-part review of the epidemiology and control of paratuberculosis in dairy herds. Several ne... Read More about A review of paratuberculosis in dairy herds — Part 2: On-farm control.

Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities and Perspectives (2019)
Journal Article
Wang, J.-L., Zhang, N.-Z., Li, T.-T., He, J.-J., Elsheikha, H. M., & Zhu, X.-Q. (2019). Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities and Perspectives. Trends in Parasitology, 35(3), 239-253. https://doi.org/10.1016/j.pt.2019.01.005

Important progress has been made in understanding how immunity is elicited against Toxoplasma gondii - a complex pathogen with multiple mechanisms of immune evasion. Many vaccine candidates have been tested using various strategies in animal models.... Read More about Advances in the Development of Anti-Toxoplasma gondii Vaccines: Challenges, Opportunities and Perspectives.

Introductory Chapter: Veterinary Anatomy and Physiology (2019)
Book Chapter
Kubale, V., Cousins, E., Bailey, C., El-Gendy, S. A., & Rutland, C. S. (2019). Introductory Chapter: Veterinary Anatomy and Physiology. In C. S. Rutland, & V. Kubale (Eds.), Veterinary anatomy and physiology (1-13). InTech. https://doi.org/10.5772/intechopen.82412

Responsible use of antibiotics on sheep farms: application at farm level (2019)
Journal Article
Lovatt, F., Duncan, J., & Hinde, D. (2019). Responsible use of antibiotics on sheep farms: application at farm level. In Practice, 41(1), 23-33. https://doi.org/10.1136/inp.k5370

There is currently global concern over rising levels of antibiotic resistance among commensal and pathogenic bacteria in human and animal populations. Unless urgent action is taken by the medical and veterinary professions, it is thought that we will... Read More about Responsible use of antibiotics on sheep farms: application at farm level.

Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus? (2019)
Journal Article
Morandi, E., Tanasescu, R., Tarlington, R., Constantin-Teodosiu, D., & Gran, B. (2019). Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?. Frontiers in Immunology, 9, Article 3092. https://doi.org/10.3389/fimmu.2018.03092

The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). The MS-related retrovirus (MSRV/HERV-W) has the potential to activate inflammatory immunity, which could promote both susceptibility and progres... Read More about Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?.

The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis (2019)
Journal Article
Tarlinton, R., Khaibullin, T., Granatov, E., Martynova, E., Rizvanov, A., & Khaiboullina, S. (2019). The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis. International Journal of Molecular Sciences, 20(2), 1-16. https://doi.org/10.3390/ijms20020303

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease of unknown ethology targeting the central nervous system (CNS). MS has a polysymptomatic onset and is usually first diagnosed between the ages of 20–40 years. The pathology of the... Read More about The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis.

Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes (2019)
Journal Article
Izquierdo, A., Fahrenberger, M., Persampieri, T., Benedict, M. Q., Giles, T., Catteruccia, F., Emes, R. D., & Dottorini, T. (2019). Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes. Life Science Alliance, 2(1), Article e00191. https://doi.org/10.26508/lsa.201800191

Modifications in gene expression determine many of the phenotypic differentiations between closely related species. This is particularly evident in reproductive tissues, where evolution of genes is more rapid, facilitating the appearance of distinct... Read More about Evolution of gene expression levels in the male reproductive organs of Anopheles mosquitoes.