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All Outputs (76)

Association between serum urate, gout and comorbidities: a case–control study using data from the UK Biobank (2020)
Journal Article

Objectives To examine the association between comorbidities and serum urate (SU), gout and comorbidities, and to determine whether the association between gout and comorbidities is independent of SU. Methods We performed a case-control study using UK... Read More about Association between serum urate, gout and comorbidities: a case–control study using data from the UK Biobank.

BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK (2020)
Journal Article

Objectives: To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal fo... Read More about BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK.

Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic (2020)
Journal Article

Objectives: To quantify the risk of death among people with rare autoimmune rheumatic diseases (RAIRD) during the UK 2020 COVID-19 pandemic compared with the general population, and compared with their pre-COVID risk. Methods: We conducted a cohort s... Read More about Risk of death among people with rare autoimmune diseases compared with the general population in England during the 2020 COVID-19 pandemic.

Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT (2020)
Journal Article

Background: Systematic reviews suggest that narrowband ultraviolet B light combined with treatments such as topical corticosteroids may be more effective than monotherapy for vitiligo. Objective: To explore the clinical effectiveness and cost-effecti... Read More about Home-based narrowband UVB, topical corticosteroid or combination for children and adults with vitiligo: HI-light vitiligo three-arm RCT.

Constitutional morphological features and risk of hip osteoarthritis: a case–control study using standard radiographs (2020)
Journal Article

© Author(s) (or their employer(s)) 2020. No commercial re-use. See rights and permissions. Published by BMJ. Objectives: To evaluate the risk of association with hip osteoarthritis (OA) of 14 morphological features measured on standard antero-posteri... Read More about Constitutional morphological features and risk of hip osteoarthritis: a case–control study using standard radiographs.

Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials (2020)
Journal Article

OBJECTIVES: To determine individual responses to ibuprofen gel or capsaicin cream for painful, radiographic knee OA using a series of n-of-1 trials. METHODS: Twenty-two participants were allocated 5% ibuprofen gel (A) and 0.025% capsaicin cream (B) i... Read More about Individual responses to topical ibuprofen gel or capsaicin cream for painful knee osteoarthritis: a series of n-of-1 trials.

Optimising recruitment to the HAND-1 RCT feasibility study: integration of the QuinteT Recruitment Intervention (QRI) (2020)
Journal Article

© 2020, The Author(s). Background: Recruitment to randomised controlled trials (RCTs) can be challenging, with most trials not reaching recruitment targets. Randomised feasibility studies can be set up prior to a main trial to identify and overcome r... Read More about Optimising recruitment to the HAND-1 RCT feasibility study: integration of the QuinteT Recruitment Intervention (QRI).

Fostering global data sharing: Highlighting the recommendations of the Research Data Alliance COVID-19 working group (2020)
Journal Article

© 2020 Austin CC et al. The systemic challenges of the COVID-19 pandemic require cross-disciplinary collaboration in a global and timely fashion. Such collaboration needs open research practices and the sharing of research outputs, such as data and c... Read More about Fostering global data sharing: Highlighting the recommendations of the Research Data Alliance COVID-19 working group.

An economic evaluation of the randomized controlled trial of topical corticosteroid and home-based narrowband ultraviolet B for active and limited vitiligo (the HI-Light Vitiligo Trial)* (2020)
Journal Article

Background: Economic evidence for vitiligo treatments is absent. Objectives: To determine the cost-effectiveness of (i) handheld narrowband ultraviolet B (NB-UVB) and (ii) a combination of topical corticosteroid (TCS) and NB-UVB compared with TCS alo... Read More about An economic evaluation of the randomized controlled trial of topical corticosteroid and home-based narrowband ultraviolet B for active and limited vitiligo (the HI-Light Vitiligo Trial)*.

Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT (2020)
Journal Article

Background: Scaphoid fractures account for 90% of carpal fractures and occur predominantly in young men. Immediate surgical fixation of this fracture has increased. Objective: To compare the clinical effectiveness and cost-effectiveness of surgical f... Read More about Surgical fixation compared with cast immobilisation for adults with a bicortical fracture of the scaphoid waist: the SWIFFT RCT.

Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis (2020)
Journal Article

Objectives: Synovitis in symptomatic knee osteoarthritis (KOA) is common and is associated with joint symptoms. Optimal synovial measurement on magnetic resonance imaging (MRI) is however, unclear. Our aims were to examine the relationship between MR... Read More about Quantitative and Semi-Quantitative Assessment of Synovitis on MRI and the Relationship with Symptoms in Symptomatic Knee Osteoarthritis.

Estimation of the burden of shielding among a cross-section of patients attending rheumatology clinics with SLE-data from the BSR audit of systemic lupus erythematosus (2020)
Journal Article

Objectives: We aimed to estimate what proportion of people with SLE attending UK rheumatology clinics would be categorized as being at high risk from coronavirus disease 2019 (COVID-19) and therefore asked to shield, and explore what implications thi... Read More about Estimation of the burden of shielding among a cross-section of patients attending rheumatology clinics with SLE-data from the BSR audit of systemic lupus erythematosus.

An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK (2020)
Journal Article

Objectives: To explore health care professionals (HCPs) experiences and challenges in diagnosing suspected lower limb cellulitis. Setting: UK nationwide. Participants: 20 qualified HCPs, who had a minimum of two years clinical experience as a... Read More about An interview study to determine the experiences of cellulitis diagnosis amongst health care professionals in the UK.