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BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK

Pearce, Fiona A.; Rutter, Megan; Sandhu, Ravinder; Batten, Rebecca L; Garner, Rozeena; Little, Jayne; Narayan, Nehal; Sharp, Charlotte A.; Bruce, Ian N.; Erb, Nicola; Griffiths, Bridget; Guest, Hannah; Macphie, Elizabeth; Packham, Jon; Hiley, Chris; Obrenovic, Karen; Rivett, Ali; Gordon, Caroline; Lanyon, Peter C.

BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK Thumbnail


Authors

FIONA PEARCE Fiona.Pearce@nottingham.ac.uk
Clinical Associate Professor

Megan Rutter

Ravinder Sandhu

Rebecca L Batten

Rozeena Garner

Jayne Little

Nehal Narayan

Charlotte A. Sharp

Ian N. Bruce

Nicola Erb

Bridget Griffiths

Hannah Guest

Elizabeth Macphie

Jon Packham

Chris Hiley

Karen Obrenovic

Ali Rivett

Caroline Gordon

Peter C. Lanyon



Abstract

Objectives: To assess the baseline care provided to patients with SLE attending UK Rheumatology units, audited against standards derived from the recently published BSR guideline for the management of adults with SLE, the NICE technology appraisal for belimumab, and NHS England's clinical commissioning policy for rituximab. Methods: SLE cases attending outpatient clinics during any 4-week period between February and June 2018 were retrospectively audited to assess care at the preceding visit. The effect of clinical environment (general vs dedicated CTD/vasculitis clinic and specialized vs non-specialized centre) were tested. Bonferroni's correction was applied to the significance level. Results: Fifty-one units participated. We audited 1021 episodes of care in 1003 patients (median age 48 years, 74% diagnosed >5 years ago). Despite this disease duration, 286 (28.5%) patients had active disease. Overall in 497 (49%) clinic visits, it was recorded that the patient was receiving prednisolone, including in 28.5% of visits where disease was assessed as inactive. Low documented compliance (

Citation

Pearce, F. A., Rutter, M., Sandhu, R., Batten, R. L., Garner, R., Little, J., …Lanyon, P. C. (2021). BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: Baseline multi-centre audit in the UK. Rheumatology, 60(3), 1480-1490. https://doi.org/10.1093/rheumatology/keaa759

Journal Article Type Article
Acceptance Date Oct 13, 2020
Online Publication Date Dec 8, 2020
Publication Date Mar 1, 2021
Deposit Date Oct 14, 2020
Publicly Available Date Mar 28, 2024
Journal Rheumatology (United Kingdom)
Electronic ISSN 1462-0332
Publisher Oxford University Press (OUP)
Peer Reviewed Peer Reviewed
Volume 60
Issue 3
Pages 1480-1490
DOI https://doi.org/10.1093/rheumatology/keaa759
Keywords Pharmacology (medical); Rheumatology
Public URL https://nottingham-repository.worktribe.com/output/4962818
Publisher URL https://academic.oup.com/rheumatology/advance-article-abstract/doi/10.1093/rheumatology/keaa759/6027899?redirectedFrom=fulltext
Additional Information This is a pre-copyedited, author-produced version of an article accepted for publication in Rheumatology following peer review. The version of record Fiona A Pearce, Megan Rutter, Ravinder Sandhu, Rebecca L Batten, Rozeena Garner, Jayne Little, Nehal Narayan, Charlotte A Sharp, Ian N Bruce, Nicola Erb, Bridget Griffiths, Hannah Guest, Elizabeth Macphie, Jon Packham, Chris Hiley, Karen Obrenovic, Ali Rivett, Caroline Gordon, Peter C Lanyon, BSR guideline on the management of adults with systemic lupus erythematosus (SLE) 2018: baseline multi-centre audit in the UK, Rheumatology, , keaa759 is available online at: https://doi.org/10.1093/rheumatology/keaa759

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