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All Outputs (72)

Influence of Social Support, Financial Status, and Lifestyle on the Disparity Between Inflammation and Disability in Rheumatoid Arthritis (2022)
Journal Article

Objective: To investigate how social support, financial status, and lifestyle influence the development of excess disability in rheumatoid arthritis (RA). Methods: Data were obtained from the Étude et Suivi des Polyarthrites Indifférenciées Récentes... Read More about Influence of Social Support, Financial Status, and Lifestyle on the Disparity Between Inflammation and Disability in Rheumatoid Arthritis.

Medio-dorsal thalamic dysconnectivity in chronic knee pain: A possible mechanism for negative affect and pain comorbidity (2022)
Journal Article

The reciprocal interaction between pain and negative affect is acknowledged but pain-related alterations in brain circuits involved in this interaction, such as the mediodorsal thalamus (MDThal), still require a better understanding. We sought to inv... Read More about Medio-dorsal thalamic dysconnectivity in chronic knee pain: A possible mechanism for negative affect and pain comorbidity.

How people wake up is associated with previous night’s sleep together with physical activity and food intake (2022)
Journal Article

How people wake up and regain alertness in the hours after sleep is related to how they are sleeping, eating, and exercising. Here, in a prospective longitudinal study of 833 twins and genetically unrelated adults, we demonstrate that how effectively... Read More about How people wake up is associated with previous night’s sleep together with physical activity and food intake.

A proposed methodology for uncertainty extraction and verification in priority setting partnerships with the James Lind Alliance: an example from the Common Conditions Affecting the Hand and Wrist Priority Setting Partnership (2022)
Journal Article

Background: To report our recommended methodology for extracting and then confirming research uncertainties – areas where research has failed to answer a research question – derived from previously published literature during a broad scope Priority S... Read More about A proposed methodology for uncertainty extraction and verification in priority setting partnerships with the James Lind Alliance: an example from the Common Conditions Affecting the Hand and Wrist Priority Setting Partnership.

The impact of repeated vaccination on relative influenza vaccine effectiveness among vaccinated adults in the United Kingdom (2022)
Journal Article

Annual seasonal influenza vaccination is recommended for individuals at high risk of developing post-infection complications in many locations. However, reduced vaccine immunogenicity and effectiveness have been observed among repeat vaccinees in som... Read More about The impact of repeated vaccination on relative influenza vaccine effectiveness among vaccinated adults in the United Kingdom.

A practical guide to implementing a successful social media recruitment strategy: lessons from the Eczema Monitoring Online trial (2022)
Journal Article

Background: Participant recruitment into clinical trials remains challenging. The global increase in the number of social media users has accelerated the use of social media as a modality of recruitment, particularly during the COVID-19 pandemic when... Read More about A practical guide to implementing a successful social media recruitment strategy: lessons from the Eczema Monitoring Online trial.

Postprandial Responses to a Standardised Meal in Hypertension: The Mediatory Role of Visceral Fat Mass (2022)
Journal Article

Postprandial insulinaemia, triglyceridaemia and measures of inflammation are thought to be more closely associated with cardiovascular risk than fasting measures. Although hypertension is associated with altered fasting metabolism, it is unknown as t... Read More about Postprandial Responses to a Standardised Meal in Hypertension: The Mediatory Role of Visceral Fat Mass.

How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals (2022)
Journal Article

We undertook a survey of UK healthcare professionals through the UKDCTN and BDNG to understand clinicians’ routine practice prescribing oral isotretinoin for treatment of acne vulgaris (acne). We also wanted to understand clinicians’ experiences and... Read More about How is oral isotretinoin prescribed for the treatment of acne vulgaris? Results from a UK Dermatology Clinical Trials Network (UKDCTN) and British Dermatological Nursing Group (BDNG) survey of health professionals.

Menopause is associated with postprandial metabolism, metabolic health and lifestyle: The ZOE PREDICT study (2022)
Journal Article

Background: The menopause transition is associated with unfavourable alterations in health. However, postprandial metabolic changes and their mediating factors are poorly understood. Methods: The PREDICT 1 UK cohort (n=1002; pre- n=366, peri- n=5... Read More about Menopause is associated with postprandial metabolism, metabolic health and lifestyle: The ZOE PREDICT study.

Measuring Atopic Eczema Control and Itch Intensity in Clinical Practice: A Consensus Statement from the Harmonising Outcome Measures for Eczema in Clinical Practice (HOME-CP) Initiative (2022)
Journal Article

Importance: Measuring outcomes in clinical practice can aid patient care, quality improvement, and real-world evidence generation. The Harmonising Outcome Measures for Eczema (HOME) Clinical Practice initiative is developing a list of validated, feas... Read More about Measuring Atopic Eczema Control and Itch Intensity in Clinical Practice: A Consensus Statement from the Harmonising Outcome Measures for Eczema in Clinical Practice (HOME-CP) Initiative.

International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia (2022)
Journal Article

Objectives: To develop evidence-based expert recommendations for non-pharmacological treatments for pain, fatigue, sleep problems, and depression in fibromyalgia. Methods: An international, multidisciplinary Delphi exercise was conducted. Authors of... Read More about International, multidisciplinary Delphi consensus recommendations on non-pharmacological interventions for fibromyalgia.

Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD) (2022)
Journal Article

Objective: In order to facilitate data pooling between studies, we explored harmonisation of patient-reported outcome measures (PROMs) in people with knee pain due to osteoarthritis or knee trauma, using the Patient Acceptable Symptom State scores (P... Read More about Harmonising knee pain patient-reported outcomes: a systematic literature review and meta-analysis of Patient Acceptable Symptom State (PASS) and individual participant data (IPD).

Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players (2022)
Journal Article

Abstract The purpose of this study was to compare basketball performance markers one year prior to initial severe lower extremity injury, including ankle, knee, and hip injuries, to one- and two-years following injury during the regular NBA season. P... Read More about Return to performance following severe ankle, knee, and hip injuries in National Basketball Association players.

Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic (2022)
Journal Article

Objectives To explore barriers and facilitators to COVID-19, influenza, and pneumococcal vaccine uptake in immunosuppressed adults with immune-mediated inflammatory diseases (IMIDs). Methods Recruiting through national patient charities and a local h... Read More about Barriers and facilitators to vaccination uptake against COVID-19, influenza, and pneumococcal pneumonia in immunosuppressed adults with immune-mediated inflammatory diseases: A qualitative interview study during the COVID-19 pandemic.

Is routine laboratory testing in healthy young patients taking isotretinoin necessary – a critically appraised topic (2022)
Journal Article

Clinical question: Is monitoring of liver function, lipids and full blood count necessary in healthy people taking isotretinoin? Background: Routine blood testing was recommended in the original licence for Roaccutane™ (isotretinoin) in 1983. In r... Read More about Is routine laboratory testing in healthy young patients taking isotretinoin necessary – a critically appraised topic.