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All Outputs (532)

Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data (2014)
Journal Article

Background Licensing arrangements for nicotine replacement therapy (NRT) in the UK were broadened in 2005 to allow prescribing to pregnant smokers. However, estimates of NRT prescribing in pregnant females in the UK are currently lacking. Aim To... Read More about Prescribing of nicotine replacement therapy in and around pregnancy: a population-based study using primary care data.

Multicentre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care (2014)
Journal Article

Background: Regular physical activity (PA) reduces the risk of falls and hip fractures, and mortality from all causes. However, PA levels are low in the older population and previous intervention studies have demonstrated only modest, short-term impr... Read More about Multicentre cluster randomised trial comparing a community group exercise programme with home based exercise with usual care for people aged 65 and over in primary care.

The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation (2014)
Journal Article

Background: Smoking during pregnancy causes many adverse pregnancy and birth outcomes. Nicotine replacement therapy (NRT) is effective for cessation outside pregnancy but efficacy and safety in pregnancy are unknown. We hypothesised that NRT would in... Read More about The SNAP trial: A randomised placebo-controlled trial of nicotine replacement therapy in pregnancy - Clinical effectiveness and safety until 2 years after delivery, with economic evaluation.

The Optimal Study: describing the key components of optimal health care delivery to UK care home residents: a research protocol (2014)
Journal Article

Long term institutional care in the UK is provided by care homes. Residents have prevalent cognitive impairment and disability, have multiple diagnoses and are subject to polypharmacy. Prevailing models of healthcare provision - ad hoc, reactive and... Read More about The Optimal Study: describing the key components of optimal health care delivery to UK care home residents: a research protocol.

Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores (2014)
Journal Article

Objective: To develop and validate risk algorithms (QBleed) for estimating the absolute risk of upper gastrointestinal and intracranial bleed for patients with and without anticoagulation aged 21-99 years in primary care. Design: Open cohort study... Read More about Predicting risk of upper gastrointestinal bleed and intracranial bleed with anticoagulants: cohort study to derive and validate the QBleed scores.

Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial (2014)
Journal Article

Background: The use of nicotine replacement therapy before quitting smoking is called nicotine preloading. Standard smoking cessation protocols suggest commencing nicotine replacement therapy only on the first day of quitting smoking (quit day) aimin... Read More about Nicotine patch preloading for smoking cessation (the preloading trial): study protocol for a randomized controlled trial.

Exploring safety systems for dispensing in community pharmacies: Focusing on how staff relate to organizational components (2014)
Journal Article

Background: Identifying risk is an important facet of a safety practice in an organization. To identify risk, all components within a system of operation should be considered. In clinical safety practice, a team of people, technologies, procedures an... Read More about Exploring safety systems for dispensing in community pharmacies: Focusing on how staff relate to organizational components.

Parents' responses to receiving sickle cell or cystic fibrosis carrier results for their child following newborn screening (2014)
Journal Article

Universal newborn screening for sickle cell disorders and cystic fibrosis aims to enable the early identification and treatment of affected babies. Screening can also identify infants who are healthy carriers, with carrier results being the commonest... Read More about Parents' responses to receiving sickle cell or cystic fibrosis carrier results for their child following newborn screening.

Comparison of cotinine levels in pregnant women while smoking and when using nicotine replacement therapy (2014)
Journal Article

BACKGROUND: Nicotine replacement therapy (NRT) helps smokers quit smoking, but trials indicate that there is no evidence that it is effective during pregnancy. As metabolism increases during pregnancy, NRT may deliver insufficient nicotine to allevia... Read More about Comparison of cotinine levels in pregnant women while smoking and when using nicotine replacement therapy.

Cost-effectiveness of interventions for increasing the possession of functioning smoke alarms in households with pre-school children: a modelling study (2014)
Journal Article

Background The UK has one of the highest rates for deaths from fire and flames in children aged 0-14 years compared to other high income countries. Evidence shows that smoke alarms can reduce the risk of fire-related injury but little exists on th... Read More about Cost-effectiveness of interventions for increasing the possession of functioning smoke alarms in households with pre-school children: a modelling study.

Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data (2014)
Journal Article

Objectives: To report methods used to assemble a contemporary pregnancy cohort for investigating influences on smoking behaviour before, during and after pregnancy and to report characteristics of women recruited. Design: Longitudinal cohort surve... Read More about Longitudinal cohort survey of women's smoking behaviour and attitudes in pregnancy: study methods and baseline data.

The effect of the electronic transmission of prescriptions on dispensing errors and prescription enhancements made in English community pharmacies: a naturalistic stepped wedge study (2014)
Journal Article

Objectives: To compare prevalence and types of dispensing errors and pharmacists’ labelling enhancements, for prescriptions transmitted electronically versus paper prescriptions. Design: Naturalistic stepped wedge study. Setting: 15 English communi... Read More about The effect of the electronic transmission of prescriptions on dispensing errors and prescription enhancements made in English community pharmacies: a naturalistic stepped wedge study.