The survival of patients with high grade glioma from different ethnic groups in South East England

Ratneswaren, T.; Jack, R. M.; Tataru, D.; Davies, E. A.

Abstract

© 2014, Springer Science+Business Media New York. Studies in the United States (US) have reported varying treatment and survival for patients with high grade glioma from different ethnic groups. This study investigates for the first time whether differences also exist in the United Kingdom (UK). This population-based cohort study used cancer registration data for 4,845 patients diagnosed in South East England between 2000 and 2009. Linked self-assigned ethnicity data within Hospital Episode Statistics were used to define White, Indian, Pakistani, Bangladeshi, Black Caribbean, Black African, Other and Not known groups. Logistic regression was used to generate odds ratios for a record of receipt of treatment (surgery, radiotherapy and chemotherapy), adjusting for sex, age, morphology, socioeconomic deprivation and comorbidity in each ethnic group. Hazard ratios were generated using Cox regression, adjusting for sex, age, morphology, socioeconomic deprivation, comorbidity and treatment. The overall one-year survival was 28.4 %. Ethnicity data was available for 3,793 (78 %) patients. Receipt of treatment was generally similar between different ethnic groups after adjustment for sex, age, morphology, socioeconomic deprivation and comorbidity. After adjustment for potential confounders, the Indian (HR 0.72, p = 0.037) and Other groups (HR 0.76, p = 0.003) had better survival, while the Not known group (HR 1.34, p 

Citation

Ratneswaren, T., Jack, R. M., Tataru, D., & Davies, E. A. (2014). The survival of patients with high grade glioma from different ethnic groups in South East England. Journal of Neuro-Oncology, 120(3), 531-536. https://doi.org/10.1007/s11060-014-1582-3

• Journal Article Type: Article
• Acceptance Date: Aug 6, 2014
• Online Publication Date: Aug 26, 2014
• Publication Date: Nov 18, 2014
• Deposit Date: Apr 26, 2021
• Journal: Journal of Neuro-Oncology
• Print ISSN: 0167-594X
• Electronic ISSN: 1573-7373
• Publisher: Springer Verlag
• Peer Reviewed: Peer Reviewed
• Volume: 120
• Issue: 3
• Pages: 531-536
• DOI: https://doi.org/10.1007/s11060-014-1582-3
• Public URL: https://nottingham-repository.worktribe.com/output/3223718
• Publisher URL: https://link.springer.com/article/10.1007%2Fs11060-014-1582-3