All Outputs (26)

Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis (2022)
Journal Article
Morton, A. J., Rashid, A., Shim, J. S., West, J., Humes, D. J., & Grainge, M. J. (2023). Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis. ANZ Journal of Surgery, 93(1-2), 42-53. https://doi.org/10.1111/ans.18059

Background: As rectal cancer survival increases, more patients survive with potentially severe, long-term gastrointestinal and genitourinary complications from radiotherapy. The burden of these complications for patients and healthcare services is un... Read More about Long-term adverse effects and healthcare burden of rectal cancer radiotherapy: systematic review and meta-analysis.

The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy (2022)
Journal Article
Lewis-Lloyd, C. A., Humes, D. J., West, J., Peacock, O., & Crooks, C. J. (2022). The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy. Annals of Surgery, 276(3), E177-E184. https://doi.org/10.1097/SLA.0000000000005563

Objective: To assess the impact of current guidelines by reporting weekly postoperative postdischarge venous thromboembolism (VTE) rates. Summary Background Data: Disparity exists between the postoperative thromboprophylaxis duration colectomy patien... Read More about The Duration and Magnitude of Postdischarge Venous Thromboembolism Following Colectomy.

Time Trends in the Incidence Rates of Venous Thromboembolism Following Colorectal Resection by Indication and Operative Technique (2022)
Journal Article
Lewis-Lloyd, C. A., Crooks, C. J., West, J., Peacock, O., & Humes, D. J. (2022). Time Trends in the Incidence Rates of Venous Thromboembolism Following Colorectal Resection by Indication and Operative Technique. Colorectal Disease, 24(11), 1405-1415. https://doi.org/10.1111/codi.16233

Aim It is important for patient safety to assess if international changes in perioperative care, such as focus on venous thromboembolism (VTE) prevention and minimally invasive surgery have reduced the high post colectomy VTE risks previously report... Read More about Time Trends in the Incidence Rates of Venous Thromboembolism Following Colorectal Resection by Indication and Operative Technique.

Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation (2021)
Journal Article
Bailey, J. A., Weller, J., Chapman, C., Ford, A., Hardy, K., Oliver, S., …Banerjea, A. (2021). Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation. BJS Open, 5(2), Article zraa056. https://doi.org/10.1093/bjsopen/zraa056

Background A novel pathway incorporating faecal immunochemical testing (FIT) for rapid colorectal cancer diagnosis (RCCD) was introduced in 2017. This paper reports on the service evaluation after 2 years of pathway implementation. Methods The R... Read More about Faecal immunochemical testing and blood tests for prioritization of urgent colorectal cancer referrals in symptomatic patients: a 2-year evaluation.

Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study (2021)
Journal Article
Adiamah, A., Ban, L., Otete, H., Crooks, C. J., West, J., & Humes, D. J. (2021). Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study. BJS Open, 5(2), https://doi.org/10.1093/bjsopen/zraa073

BACKGROUND: The management of perforated diverticular disease has changed in the past 10 years with a move towards less surgical intervention. This population-based cohort study aimed to define the risk of death and readmission following non-operativ... Read More about Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study.

Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer (2020)
Journal Article
Chapman, C. J., Banerjea, A., Humes, D. J., Allen, J., Oliver, S., Ford, A., …Morling, J. R. (2021). Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer. Clinical Chemistry and Laboratory Medicine, 59(4), 721-728. https://doi.org/10.1515/cclm-2020-1170

Objectives: Currently NICE recommends the use of faecal immunochemical test (FIT) at faecal haemoglobin concentrations (f-Hb) of 10 μg Hb/g faeces to stratify for colorectal cancer (CRC) risk in symptomatic populations. This f-Hb cut-off is advised a... Read More about Choice of faecal immunochemical test matters: comparison of OC-Sensor and HM-JACKarc, in the assessment of patients at high risk of colorectal cancer.

Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis (2020)
Journal Article
Adiamah, A., Ban, L., Hammond, J., Jepsen, P., West, J., & Humes, D. .. (2020). Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis. Alcohol and Alcoholism, 55(5), 497–511. https://doi.org/10.1093/alcalc/agaa043

Aims: This meta-analysis aimed to define the perioperative risk of mortality in patients with alcoholic liver disease (ALD) undergoing extrahepatic gastrointestinal surgery. Methods: Systematic searches of Embase, Medline and CENTRAL were undertak... Read More about Mortality after extrahepatic gastrointestinal and abdominal wall surgery in patients with alcoholic liver disease: A systematic review and meta-analysis.

Thrombocytosis helps to stratify risk of colorectal cancer in patients referred on a 2-week-wait pathway (2020)
Journal Article
Bailey, J. A., Hanbali, N., Premji, K., Bunce, J., Mashlab, S., Simpson, J. A., …Banerjea, A. (2020). Thrombocytosis helps to stratify risk of colorectal cancer in patients referred on a 2-week-wait pathway. International Journal of Colorectal Disease, https://doi.org/10.1007/s00384-020-03597-9

GP access to FIT increases the proportion of colorectal cancers detected on urgent pathways in symptomatic patients in Nottingham (2020)
Journal Article
Bailey, J., Khawaja, A., Andrews, H., Weller, J., Chapman, C., Morling, J., …Banerjea, A. (2021). GP access to FIT increases the proportion of colorectal cancers detected on urgent pathways in symptomatic patients in Nottingham. Surgeon, 19(2), 93-102. https://doi.org/10.1016/j.surge.2020.03.002

Objective Service evaluation of GP access to Faecal Immunochemical Test (FIT) for colorectal cancer (CRC) detection in Nottinghamshire and use of FIT for “rule out”, “rule in” and “first test selection”. Design Retrospective audit of FIT results... Read More about GP access to FIT increases the proportion of colorectal cancers detected on urgent pathways in symptomatic patients in Nottingham.

Early clinical outcomes of a rapid colorectal cancer diagnosis pathway using faecal immunochemical testing in Nottingham (2019)
Journal Article
Chapman, C., Thomas, C., Morling, J., Tangri, A., Oliver, S., Simpson, J. A., …Banerjea, A. (2020). Early clinical outcomes of a rapid colorectal cancer diagnosis pathway using faecal immunochemical testing in Nottingham. Colorectal Disease, 22(6), 679-688. https://doi.org/10.1111/codi.14944

Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study (2019)
Journal Article
Henry, M., Abdul-Sultan, A., Walker, A., West, J., & Humes, D. (2019). Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study. Digestive Surgery, 37(1), 32-38. https://doi.org/10.1159/000496435

Background: This study aimed to identify burden and risk of VTE associated with cholecystectomy in England. Methods: An historical cohort study of cholecystectomy patients from 2001-2011 was undertaken using linked primary (Clinical Practice... Read More about Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study.

A service evaluation of FIT and anaemia for risk stratification in the two week wait pathway for colorectal cancer (2019)
Journal Article
Chapman, C., Bunce, J., Oliver, S., Ng, O., Tangri, A., Rogers, R., …Banerjea, A. (2019). A service evaluation of FIT and anaemia for risk stratification in the two week wait pathway for colorectal cancer. BJS Open, 3(3), 395-402. https://doi.org/10.1002/bjs5.50131

Introduction: New national guidance on urgent referral for investigation for Colorectal Cancer (CRC) included faecal occult blood testing in 2015. We evaluated faecal immunochemical testing (FIT) and anaemia as risk stratification tools in symptomati... Read More about A service evaluation of FIT and anaemia for risk stratification in the two week wait pathway for colorectal cancer.

Changing autonomy in operative experience through UK general surgery training: a national cohort study (2018)
Journal Article
Elsey, E. J., Griffiths, G., West, J., & Humes, D. J. (2019). Changing autonomy in operative experience through UK general surgery training: a national cohort study. Annals of Surgery, 269(3), 399-406. https://doi.org/10.1097/sla.0000000000003032

Objectives:To determine the operative experience of UK general surgery trainees and assess the changing procedural supervision and acquisition of competency assessments through the course of training. Background Summary Data: Competency assessment... Read More about Changing autonomy in operative experience through UK general surgery training: a national cohort study.

Time out of general surgery specialty training in the UK: a national database study (2018)
Journal Article
Elsey, E. J., West, J., Griffiths, G., & Humes, D. J. (2019). Time out of general surgery specialty training in the UK: a national database study. Journal of Surgical Education, 76(1), 55-64. https://doi.org/10.1016/j.jsurg.2018.06.011

Objective General surgery specialty training in the United Kingdom takes 6 years and allows trainees to take time out of training. Studies from the United States have highlighted an increasing trend for taking time out of surgical training for res... Read More about Time out of general surgery specialty training in the UK: a national database study.

Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study (2018)
Journal Article
Humes, D., Abdul-Sultan, A., Walker, A. J., Ludvigsson, J. F., & West, J. (in press). Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study. Hernia, https://doi.org/10.1007/s10029-017-1716-6

Purpose Little is known regarding the magnitude and timing of the risk of VTE following inguinal hernia surgery. We aimed to determine the absolute and relative rates of venous thromboembolism (VTE) following planned inguinal hernia repair. Methods... Read More about Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study.

Meta-analysis of operative experiences of general surgery trainees during training (2016)
Journal Article
Elsey, E., Griffiths, G., Humes, D., & West, J. (in press). Meta-analysis of operative experiences of general surgery trainees during training. British Journal of Surgery, 104(1), https://doi.org/10.1002/bjs.10396

BACKGROUND: General surgical training curricula around the world set defined operative numbers to be achieved before completion of training. However, there are few studies reporting total operative experience in training. This systematic review aimed... Read More about Meta-analysis of operative experiences of general surgery trainees during training.

Adverse pregnancy outcomes among women with inflammatory bowel disease: a population based study from England (2016)
Journal Article
Abdul Sultan, A., West, J., Ban, L., Humes, D., Tata, L. J., Fleming, K. M., …Card, T. R. (2016). Adverse pregnancy outcomes among women with inflammatory bowel disease: a population based study from England. Inflammatory Bowel Diseases, 22(7), 1621-1630. https://doi.org/10.1097/MIB.0000000000000802

Background: There is limited contemporary population based evidence on adverse birth outcomes and pregnancy related complications for women with inflammatory bowel disease (IBD). This study provides such estimates of these risks and assesses variatio... Read More about Adverse pregnancy outcomes among women with inflammatory bowel disease: a population based study from England.

Contemporary review of risk-stratified management in acute uncomplicated and complicated diverticulitis (2016)
Journal Article
Boermeester, M. A., Humes, D., Velmahos, G. C., & Søreide, K. (in press). Contemporary review of risk-stratified management in acute uncomplicated and complicated diverticulitis. World Journal of Surgery, 40(10), https://doi.org/10.1007/s00268-016-3560-8

BACKGROUND: Acute colonic diverticulitis is a common clinical condition. Severity of the disease is based on clinical, laboratory, and radiological investigations and dictates the need for medical or surgical intervention. Recent clinical trials have... Read More about Contemporary review of risk-stratified management in acute uncomplicated and complicated diverticulitis.

Smoking and the risk of hospitalization for symptomatic diverticular disease: a population-based cohort study from Sweden (2016)
Journal Article
Humes, D., Ludvigsson, J. F., & Jarvholm, B. (2016). Smoking and the risk of hospitalization for symptomatic diverticular disease: a population-based cohort study from Sweden. Diseases of the Colon and Rectum, 59(2), https://doi.org/10.1097/dcr.0000000000000515

BACKGROUND: Current studies reporting on the risk of smoking and development of symptomatic diverticular disease have reported conflicting results. OBJECTIVE: The aim of this study was to investigate the association between smoking and symptomati... Read More about Smoking and the risk of hospitalization for symptomatic diverticular disease: a population-based cohort study from Sweden.

Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults (2016)
Journal Article
Humes, D., Walker, A. J., Hunt, B., Sultan, A. A., Ludvigsson, J. F., & West, J. (2016). Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults. British Journal of Surgery, 103(4), 443-450. https://doi.org/10.1002/bjs.10091

BACKGROUND: Appendicectomy is the commonest intra-abdominal emergency surgical procedure, and little is known regarding the magnitude and timing of the risk of venous thromboembolism (VTE) after surgery. This study aimed to determine absolute and rel... Read More about Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults.