All Outputs (106)

Grassmann variables and pseudoclassical Nuclear Magnetic Resonance (2016)
Journal Article

The concept of a propagator is useful and is a well-known object in diffusion NMR experiments. Here, we investigate the related concept; the propagator for the magnetization or the Green's function of the Torrey-Bloch equations. The magnetization pro... Read More about Grassmann variables and pseudoclassical Nuclear Magnetic Resonance.

James G. White MD, 1929–2016 (2016)
Journal Article

Potential pitfalls when denoising resting state fMRI data using nuisance regression (2016)
Journal Article

In resting state fMRI, it is necessary to remove signal variance associated with noise sources, leaving cleaned fMRI time-series that more accurately reflect the underlying intrinsic brain fluctuations of interest. This is commonly achieved through n... Read More about Potential pitfalls when denoising resting state fMRI data using nuisance regression.

Understanding the relationship between costs and the modified Rankin Scale: a systematic review, multidisciplinary consensus and recommendations for future studies (2016)
Journal Article

Background and purpose: Cost-of-illness studies often describe a single aggregate cost of a disease state. This approach is less helpful for a condition with a spectrum of outcomes like stroke. The modified Rankin Scale is the most commonly used outc... Read More about Understanding the relationship between costs and the modified Rankin Scale: a systematic review, multidisciplinary consensus and recommendations for future studies.

Assessing microstructural substrates of white matter abnormalities: a comparative study using DTI and NODDI (2016)
Journal Article

Neurite orientation dispersion and density imaging (NODDI) enables more specific characterization of tissue microstructure by estimating neurite density (NDI) and orientation dispersion (ODI), two key contributors to fractional anisotropy (FA). The p... Read More about Assessing microstructural substrates of white matter abnormalities: a comparative study using DTI and NODDI.

Novel strategies for assessing platelet reactivity (2016)
Journal Article

There are many approaches to assessing platelet reactivity and many uses for such measurements. Initially, measurements were based on the ability of platelets separated from other blood cells to aggregate together following activation with an appropr... Read More about Novel strategies for assessing platelet reactivity.

Terminal sterilization: conventional methods versus emerging cold atmospheric pressure plasma technology for non-viable biological tissues (2016)
Journal Article

Tissue products are susceptible to microbial contamination from different sources, which may cause disease transmission upon transplantation. Terminal sterilization using gamma radiation, electron-beam, and ethylene oxide protocols are well-establish... Read More about Terminal sterilization: conventional methods versus emerging cold atmospheric pressure plasma technology for non-viable biological tissues.

Comodulation Enhances Signal Detection via Priming of Auditory Cortical Circuits (2016)
Journal Article

Acoustic environments are composed of complex overlapping sounds that the auditory system is required to segregate into discrete perceptual objects. The functions of distinct auditory processing stations in this challenging task are poorly understood... Read More about Comodulation Enhances Signal Detection via Priming of Auditory Cortical Circuits.

Dependency and health utilities in stroke: data to inform cost-effectiveness analyses (2016)
Journal Article

Introduction: Health utilities (HU) assign preference weights to specific health states and are required for costeffectiveness analyses. Existing HU for stroke inadequately reflect the spectrum of post-stroke disability. Using international stroke tr... Read More about Dependency and health utilities in stroke: data to inform cost-effectiveness analyses.

Decreased interferon-? induced STAT-4 activation in immune cells and clinical outcome in multiple sclerosis (2016)
Journal Article

Objectives. Interferon-? (IFN-?) is used in the treatment of multiple sclerosis (MS). IFN-? activation of signal transduction and activation of transcription (STAT)-4 is linked to its immunomodulatory effects. Previous studies suggest a type I IFN de... Read More about Decreased interferon-? induced STAT-4 activation in immune cells and clinical outcome in multiple sclerosis.

Using Acoustic Simulations of Hearing Loss to Describe Health States: Are they Feasible and Reliable to use? (2016)
Journal Article

Objectives Decisions about which treatments to provide in publicly-funded healthcare systems are partly based on the preferences of the general public. Preferences can be obtained by describing a health state before and after a treatment in word... Read More about Using Acoustic Simulations of Hearing Loss to Describe Health States: Are they Feasible and Reliable to use?.

Reductions in cortical alpha activity, enhancements in neural responses and impaired gap detection caused by sodium salicylate in awake guinea pigs (2016)
Journal Article

Tinnitus chronically affects between 10–15% of the population but, despite its prevalence, the underlying mechanisms are still not properly understood. One experimental model involves administration of high doses of sodium salicylate, as this is know... Read More about Reductions in cortical alpha activity, enhancements in neural responses and impaired gap detection caused by sodium salicylate in awake guinea pigs.

Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial. (2016)
Journal Article

OBJECTIVE: This report considers feasibility of conducting a UK trial of combination devices for tinnitus, using data from the study which evaluated different listener programmes available within the pre-market version of Oticon Alta with Tinnitus S... Read More about Pre-market version of a commercially available hearing instrument with a tinnitus sound generator: feasibility of evaluation in a clinical trial..

Modelling primary blast lung injury: current capability and future direction (2016)
Journal Article

Primary blast lung injury frequently complicates military conflict and terrorist attacks on civilian populations. The fact that it occurs in areas of conflict or unpredictable mass casualty events makes clinical study in human casualties implausible.... Read More about Modelling primary blast lung injury: current capability and future direction.

Quantification of Serial Cerebral Blood Flow in Acute Stroke Using Arterial Spin Labeling (2016)
Journal Article

Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families (2016)
Journal Article

Strong familial aggregation of schizophrenia has been reported but there is uncertainty concerning the degree of genetic contribution to the phenotypic variance of the disease. This study aimed to examine the familial aggregation and heritability of... Read More about Familial aggregation and heritability of schizophrenia and co-aggregation of psychiatric illnesses in affected families.

Therapeutic potential of transdermal glyceryl trinitrate in the management of acute stroke (2016)
Journal Article

The nitric oxide donor, glyceryl trinitrate (GTN), is a candidate treatment for the management of acute stroke with haemodynamic and potential reperfusion and neuroprotective effects. When administered as a transdermal patch during the acute and suba... Read More about Therapeutic potential of transdermal glyceryl trinitrate in the management of acute stroke.

Granulocyte-colony stimulating factor (G-CSF) for stroke: an individual patient data meta-analysis (2016)
Journal Article

Granulocyte colony stimulating factor (G-CSF) may enhance recovery from stroke through neuroprotective mechanisms if administered early, or neurorepair if given later. Several small trials suggest administration is safe but effects on efficacy are un... Read More about Granulocyte-colony stimulating factor (G-CSF) for stroke: an individual patient data meta-analysis.

Auditory compensation for head rotation is incomplete (2016)
Journal Article

Hearing is confronted by a similar problem to vision when the observer moves. The image motion that is created remains ambiguous until the observer knows the velocity of eye and/or head. One way the visual system solves this problem is to use motor c... Read More about Auditory compensation for head rotation is incomplete.

Lifetime leisure music exposure associated with increased frequency of tinnitus (2016)
Journal Article

Tinnitus has been linked to noise exposure, a common form of which is listening to music as a leisure activity. The relationship between tinnitus and type and duration of music exposure is not well understood. We conducted an internet-based populatio... Read More about Lifetime leisure music exposure associated with increased frequency of tinnitus.