All Outputs (149)

The Content and Quality of Information About Hyperacusis Presented Online (2020)
Journal Article

© 2020 American Speech-Language-Hearing Association. Purpose: Hyperacusis is a disorder characterized by reduced sound tolerance leading to ear pain, emotional distress, and reduced quality of life. Many people with hyperacusis turn to the Internet f... Read More about The Content and Quality of Information About Hyperacusis Presented Online.

The Neural Bases of Tinnitus: Lessons from Deafness and Cochlear Implants (2020)
Journal Article

Subjective tinnitus is the conscious perception of sound in the absence of any acoustic source. The literature suggests various tinnitus mechanisms, most of which invoke changes in spontaneous firing rates of central auditory neurons resulting from m... Read More about The Neural Bases of Tinnitus: Lessons from Deafness and Cochlear Implants.

A Comparison of T2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study (2020)
Journal Article

Background: T2 relaxation-based magnetic resonance imaging (MRI) signals may provide onset time for acute ischemic strokes with an unknown onset. The ability of visual and quantitative MRI-based methods in a cohort of hyperacute ischemic stroke patie... Read More about A Comparison of T2 Relaxation-Based MRI Stroke Timing Methods in Hyperacute Ischemic Stroke Patients: A Pilot Study.

Predictors and outcomes of neurological deterioration in intracerebral hemorrhage: results from the TICH-2 randomised controlled trial (2020)
Journal Article

Neurological deterioration is common after intracerebral hemorrhage (ICH). We aimed to identify the predictors and effects of neurological deterioration and whether tranexamic acid reduced the risk of neurological deterioration. Data from the Tranexa... Read More about Predictors and outcomes of neurological deterioration in intracerebral hemorrhage: results from the TICH-2 randomised controlled trial.

Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine (2020)
Journal Article

Objectives Meta-analysis based on individual patient data (IPD) from randomised trials is superior to using published summary data since it facilitates subgroup and multiple variable analyses. Guidelines and funders expect that researchers share IPD... Read More about Data sharing: experience of accessing individual patient data from completed randomised controlled trials in vascular and cognitive medicine.

Auditory dysfunction in type 2 Stickler Syndrome (2020)
Journal Article

Purpose To present the extent and site of lesion of auditory dysfunction in a large cohort of individuals with type 2 Stickler Syndrome. Type 2 Stickler syndrome results from a mutation in the gene coding for α-1 type XI pro-collagen, which has been... Read More about Auditory dysfunction in type 2 Stickler Syndrome.

Potential of mesenchymal stem cells as topical immunomodulatory cell therapies for ocular surface inflammatory disorders (2020)
Journal Article

Ocular surface inflammatory disorders (OSIDs) are a group of highly prevalent, heterogeneous diseases which display a variety of aetiologies and symptoms and are risk factors for serious complications including ocular and cornea impairment. Corneal i... Read More about Potential of mesenchymal stem cells as topical immunomodulatory cell therapies for ocular surface inflammatory disorders.

Corticocortical and Thalamocortical Changes in Functional Connectivity and White Matter Structural Integrity after Reward-Guided Learning of Visuospatial Discriminations in Rhesus Monkeys (2020)
Journal Article

The frontal cortex and temporal lobes together regulate complex learning and memory capabilities. Here, we collected resting-state functional and diffusion-weighted MRI data before and after male rhesus macaque monkeys received extensive training to... Read More about Corticocortical and Thalamocortical Changes in Functional Connectivity and White Matter Structural Integrity after Reward-Guided Learning of Visuospatial Discriminations in Rhesus Monkeys.

The impact of video games on ultrasound-guided regional anesthesia skills (2020)
Journal Article

Background: There is an association between video game practice and laparoscopic expertise in trainee surgeons. Ultrasound-guided regional anesthesia has many parallels with laparoscopic surgery. The aim of this study was to explore whether video gam... Read More about The impact of video games on ultrasound-guided regional anesthesia skills.

WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry (2020)
Journal Article

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Interprofessional learning (IPL) is essential to prepare healthcare trainees as the future public health workforce. WHIRL (Workplace Health InteRprofessional Learning) was an innovative IPL in... Read More about WHIRL Study: Workplace Health Interprofessional Learning in the Construction Industry.

Self-diagnosed COVID-19 in people with multiple sclerosis: a community-based cohort of the UK MS Register (2020)
Journal Article

Antimicrobial peptides in human corneal tissue of patients with fungal keratitis (2020)
Journal Article

Background Fungal keratitis (FK) is the leading cause of unilateral blindness in the developing world. Antimicrobial peptides (AMPs) have been shown to play an important role on human ocular surface (OS) during bacterial, viral and protozoan infectio... Read More about Antimicrobial peptides in human corneal tissue of patients with fungal keratitis.

Designing and comparing optimized pseudo-continuous Arterial Spin Labeling protocols for measurement of cerebral blood flow (2020)
Journal Article

Arterial Spin Labeling (ASL) is a non-invasive, non-contrast, perfusion imaging technique which is inherently SNR limited. It is, therefore, important to carefully design scan protocols to ensure accurate measurements. Many pseudo-continuous ASL (PCA... Read More about Designing and comparing optimized pseudo-continuous Arterial Spin Labeling protocols for measurement of cerebral blood flow.

Circadian vulnerability of cisplatin-induced ototoxicity in the cochlea (2020)
Journal Article

The chemotherapeutic agent cisplatin is renowned for its ototoxic effects. While hair cells in the cochlea are established targets of cisplatin, less is known regarding the afferent synapse, which is an essential component in the faithful temporal tr... Read More about Circadian vulnerability of cisplatin-induced ototoxicity in the cochlea.

The Prevalence and Severity of Misophonia in a UK Undergraduate Medical Student Population and Validation of the Amsterdam Misophonia Scale (2020)
Journal Article

Misophonia is a condition of abnormal emotional responses to specific auditory stimuli. There is limited information available on the prevalence of this condition. This study aimed to estimate the prevalence of misophonia in an undergraduate medical... Read More about The Prevalence and Severity of Misophonia in a UK Undergraduate Medical Student Population and Validation of the Amsterdam Misophonia Scale.

Developing a Fatigue Programme: Protocol for the Nottingham Fatigue After Stroke (NotFAST2) (2020)
Journal Article

Introduction Post-stroke fatigue is common and is one of the most distressing symptoms after stroke. It has a negative impact on physical, social and psychological functioning; it is also associated with poor outcomes and increased mortality. The... Read More about Developing a Fatigue Programme: Protocol for the Nottingham Fatigue After Stroke (NotFAST2).

Non-negative data-driven mapping of structural connections with application to the neonatal brain (2020)
Journal Article

© 2020 Mapping connections in the neonatal brain can provide insight into the crucial early stages of neurodevelopment that shape brain organisation and lay the foundations for cognition and behaviour. Diffusion MRI and tractography provide unique op... Read More about Non-negative data-driven mapping of structural connections with application to the neonatal brain.

Combination of dual-energy computed tomography and iterative metal artefact reduction to increase general quality of imaging for radiotherapy patients with high dense materials. Phantom study (2020)
Journal Article

The Benefit of Cross-Modal Reorganization on Speech Perception in Pediatric Cochlear Implant Recipients Revealed Using Functional Near-Infrared Spectroscopy (2020)
Journal Article

Cochlear implants (CIs) are the most successful treatment for severe-to-profound deafness in children. However, speech outcomes with a CI often lag behind those of normally-hearing children. Some authors have attributed these deficits to the takeover... Read More about The Benefit of Cross-Modal Reorganization on Speech Perception in Pediatric Cochlear Implant Recipients Revealed Using Functional Near-Infrared Spectroscopy.

Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID‐19 pandemic, now and in the future (2020)
Journal Article

We have provided an overview on the profound impact of COVID‐19 upon older people with Alzheimer's disease and other dementias and the challenges encountered in our management of dementia in different health‐care settings, including hospital, out‐pat... Read More about Tackling challenges in care of Alzheimer's disease and other dementias amid the COVID‐19 pandemic, now and in the future.