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Investigating tinnitus subgroups based on hearing-related difficulties (2021)
Journal Article
Beukes, E. W., Baguley, D. M., Manchaiah, V., Andersson, G., Allen, P. M., Kaldo, V., …Maidment, D. W. (2021). Investigating tinnitus subgroups based on hearing-related difficulties. International Journal of Clinical Practice, 75(10), Article e14684. https://doi.org/10.1111/ijcp.14684

Purpose Meaningfully grouping individuals with tinnitus who share a common characteristics (ie, subgrouping, phenotyping) may help tailor interventions to certain tinnitus subgroups and hence reduce outcome variability. The purpose of this study was... Read More about Investigating tinnitus subgroups based on hearing-related difficulties.

Cochlear implant user perceptions of magnetic resonance imaging (2021)
Journal Article
Dewey, R. S., & Kitterick, P. T. (2022). Cochlear implant user perceptions of magnetic resonance imaging. Cochlear Implants International, 23(1), 11-20. https://doi.org/10.1080/14670100.2021.1954748

Objectives To characterise opinions about needing to undergo MRI within the population of current cochlear implant (CI) users. Background Magnetic resonance imaging (MRI) of CI users is often associated with severe discomfort and magnet disp... Read More about Cochlear implant user perceptions of magnetic resonance imaging.

Preferential Cochleotoxicity of Cisplatin (2021)
Journal Article
Prayuenyong, P., Baguley, D. M., Kros, C. J., & Steyger, P. S. (2021). Preferential Cochleotoxicity of Cisplatin. Frontiers in Neuroscience, 15, Article 695268. https://doi.org/10.3389/fnins.2021.695268

Cisplatin-induced ototoxicity in humans is more predominant in the cochlea than in the vestibule. Neither definite nor substantial vestibular dysfunction after cisplatin treatment has been consistently reported in the current literature. Inner ear ha... Read More about Preferential Cochleotoxicity of Cisplatin.

Prevalence of Hyperacusis and Its Relation to Health: The Busselton Healthy Ageing Study (2021)
Journal Article
Smit, A. L., Stegeman, I., Eikelboom, R. H., Baguley, D. M., Bennett, R. J., Tegg-Quinn, S., …Atlas, M. D. (2021). Prevalence of Hyperacusis and Its Relation to Health: The Busselton Healthy Ageing Study. Laryngoscope, 131(12), E2887-E2896. https://doi.org/10.1002/lary.29768

Importance The prevalence of hyperacusis and its relationship with mental and general health is unknown in a nonclinical sample. Therefore, we aimed to determine the prevalence of hyperacusis and its relation with hearing, general and mental health... Read More about Prevalence of Hyperacusis and Its Relation to Health: The Busselton Healthy Ageing Study.

Quality of Life and Psychological Distress in Portuguese Older Individuals with Tinnitus (2021)
Journal Article
Haider, H. F., Ribeiro, S. F., Hoare, D. J., Fialho, G., Hall, D. A., Antunes, M., …Paço, J. (2021). Quality of Life and Psychological Distress in Portuguese Older Individuals with Tinnitus. Brain Sciences, 11(7), Article 953. https://doi.org/10.3390/brainsci11070953

Tinnitus is the perception of a sound without an external source, often associated with adverse psychological and emotional effects leading to impaired quality of life (QoL). The present study investigated QoL and psychological distress in tinnitus p... Read More about Quality of Life and Psychological Distress in Portuguese Older Individuals with Tinnitus.

Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial (2021)
Journal Article
Meek, C., Moghaddam, N. G., Evangelou, N., Oates, L. L., Topcu, G., Allen, C., & das Nair, R. (2021). Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial. Journal of Contextual Behavioral Science, 21, 158-170. https://doi.org/10.1016/j.jcbs.2021.07.001

Introduction Transitioning to secondary progressive multiple sclerosis (SPMS) is a difficult time for people, fraught with psychological uncertainty and an increase in physical disability. In parallel, healthcare appointments become less frequent, m... Read More about Acceptance-based telephone support around the time of transition to secondary progressive multiple sclerosis: A feasibility randomised controlled trial.

High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study (2021)
Journal Article
Weaver, L., Das, A., Saffaran, S., Yehya, N., Scott, T. E., Chikhani, M., …Bates, D. G. (2021). High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study. Annals of Intensive Care, 11(1), Article 109. https://doi.org/10.1186/s13613-021-00904-7

Background: There is ongoing controversy regarding the potential for increased respiratory effort to generate patient self-inflicted lung injury (P-SILI) in spontaneously breathing patients with COVID-19 acute hypoxaemic respiratory failure. However,... Read More about High risk of patient self-inflicted lung injury in COVID-19 with frequently encountered spontaneous breathing patterns: a computational modelling study.

Parametric Assessment of the Effect of Cochlear Implant Positioning on Brain MRI Artefacts at 3 T (2021)
Journal Article
Dewey, R. S., Dineen, R. A., Clemence, M., Dick, O., Bowtell, R., & Kitterick, P. T. (2021). Parametric Assessment of the Effect of Cochlear Implant Positioning on Brain MRI Artefacts at 3 T. Otology and Neurotology, 42(10), e1449-e1456. https://doi.org/10.1097/MAO.0000000000003281

Background:Brain magnetic resonance imaging in patients with cochlear implants (CIs) is impacted by image artefacts.Hypothesis:The optimal positioning of the CI to minimize artefacts is unknown. This study aimed to characterize the dependence of the... Read More about Parametric Assessment of the Effect of Cochlear Implant Positioning on Brain MRI Artefacts at 3 T.

Telehealth rehabilitation for adults with cochlear implants in response to the Covid-19 pandemic: platform selection and case studies (2021)
Journal Article
Carter, J. M., Killan, C. F., & Ridgwell, J. J. (2022). Telehealth rehabilitation for adults with cochlear implants in response to the Covid-19 pandemic: platform selection and case studies. Cochlear Implants International, 23(1), 43-51. https://doi.org/10.1080/14670100.2021.1949524

Background Effective information giving and goal setting before cochlear implantation and individualised rehabilitation following implantation are both crucial for shaping patients’ expectations and optimising outcomes. The Covid-19 pandemic led to... Read More about Telehealth rehabilitation for adults with cochlear implants in response to the Covid-19 pandemic: platform selection and case studies.

Post-keratoplasty Infectious Keratitis: Epidemiology, Risk Factors, Management, and Outcomes (2021)
Journal Article
Song, A., Deshmukh, R., Lin, H., Ang, M., Mehta, J. S., Chodosh, J., …Ting, D. S. (2021). Post-keratoplasty Infectious Keratitis: Epidemiology, Risk Factors, Management, and Outcomes. Frontiers in Medicine, 8, Article 707242. https://doi.org/10.3389/fmed.2021.707242

Post-keratoplasty infectious keratitis (PKIK) represents a unique clinical entity that often poses significant diagnostic and therapeutic challenges. It carries a high risk of serious complications such as graft rejection and failure, and less common... Read More about Post-keratoplasty Infectious Keratitis: Epidemiology, Risk Factors, Management, and Outcomes.

Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations] (2021)
Journal Article
Bath, P. M., Coleman, C. M., Gordon, A. L., Lim, W. S., & Webb, A. J. (2021). Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations]. F1000Research, 10, 1-34. https://doi.org/10.12688/f1000research.51270.1

Although the antimicrobial potential of nitric oxide (NO) is widely published, it is little used clinically. NO is a key signalling molecule modulating vascular, neuronal, inflammatory and immune responses. Endogenous antimicrobial activity is largel... Read More about Nitric oxide for the prevention and treatment of viral, bacterial, protozoal and fungal infections [version 1; peer review: 1 approved with reservations].

The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review (2021)
Journal Article
Daoud, E., Caimino, C., Akeroyd, M. A., Noreña, A. J., & Baguley, D. M. (2022). The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review. PharmacoEconomics - Open, 6, 21-32. https://doi.org/10.1007/s41669-021-00273-8

Background and objectives Tinnitus is a chronic subjective condition that impacts patients’ health-related quality of life (HRQoL) and requires multidisciplinary interventions. In health economics, quality-adjusted life years (QALYs) and willingness... Read More about The Utility of Economic Measures to Quantify the Burden of Tinnitus in Affected Individuals: A Scoping Review.

Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI (2021)
Journal Article
Dewey, R. S., Hall, D. A., Plack, C. J., & Francis, S. T. (2021). Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI. Magnetic Resonance in Medicine, 86(5), 2577-2588. https://doi.org/10.1002/mrm.28902

Purpose Detecting sound-related activity using functional MRI requires the auditory stimulus to be more salient than the intense background scanner acoustic noise. Various strategies can reduce the impact of scanner acoustic noise, including “sparse... Read More about Comparison of continuous sampling with active noise cancelation and sparse sampling for cortical and subcortical auditory functional MRI.

The effects of dual-task interference in predicting turn-ends in speech and music (2021)
Journal Article
Fisher, N. K., Hadley, L. V., Corps, R. E., & Pickering, M. J. (2021). The effects of dual-task interference in predicting turn-ends in speech and music. Brain Research, 1768, Article 147571. https://doi.org/10.1016/j.brainres.2021.147571

Determining when a partner’s spoken or musical turn will end requires well-honed predictive abilities. Evidence suggests that our motor systems are activated during perception of both speech and music, and it has been argued that motor simulation is... Read More about The effects of dual-task interference in predicting turn-ends in speech and music.

EPEN-04. SIOP EPENDYMOMA I: FINAL RESULTS, LONG TERM FOLLOW-UP AND MOLECULAR ANALYSIS OF THE TRIAL COHORT: A BIOMECA CONSORTIUM STUDY (2021)
Journal Article
Ritzmann, T. A., Chapman, R. J., Macarthur, D., Mallucci, C., Kilday, J., Thorp, N., …Grundy, R. G. (2021). EPEN-04. SIOP EPENDYMOMA I: FINAL RESULTS, LONG TERM FOLLOW-UP AND MOLECULAR ANALYSIS OF THE TRIAL COHORT: A BIOMECA CONSORTIUM STUDY. Neuro-Oncology, 23(Supplement 1), i14. https://doi.org/10.1093/neuonc/noab090.054

Introduction Surgery and radiotherapy are established childhood ependymoma treatments. The efficacy of chemotherapy has been debated. We report final results of the SIOP Ependymoma I trial, with 12-year follow-up, in the context of a post-hoc analys... Read More about EPEN-04. SIOP EPENDYMOMA I: FINAL RESULTS, LONG TERM FOLLOW-UP AND MOLECULAR ANALYSIS OF THE TRIAL COHORT: A BIOMECA CONSORTIUM STUDY.

Hyperacusis：a mini review (2021)
Journal Article
Zhang, D., Xu, Q., & Baguley, D. (2021). Hyperacusis：a mini review. Journal of Clinical Otorhinolaryngology Head and Neck Surgery (临床耳鼻咽喉头颈外科杂志), 2021(6), 563-566

Hyperacusis refers to the experience of the sound environment being perceived as overwhelming loud or painful, and this can severely affect the patient's quality of life. In China little attention has been paid to hyperacusis, and there has been litt... Read More about Hyperacusis：a mini review.

Virtual consultation for red eye (2021)
Journal Article
Ho, C. S., Avery, A. J., Livingstone, I. A., & Ting, D. S. (2021). Virtual consultation for red eye. BMJ, 373, Article n1490. https://doi.org/10.1136/bmj.n1490

This article was written with the aim of helping primary care doctors to reflect on their knowledge and skills in managing common ophthalmic condition such as red eye in the community via virtual consultations. Expert opinions (from both ophthalmolog... Read More about Virtual consultation for red eye.

Learning from a successful process evaluation in care homes (2021)
Journal Article
Allen, F., Darby, J., Cook, M., Evley, R., Godfrey, M., Horne, J., …Robinson, K. (2021). Learning from a successful process evaluation in care homes. Age and Ageing, 50(5), 1850-1853. https://doi.org/10.1093/ageing/afab139

Introduction process evaluations (PE) are increasingly used in parallel with randomised controlled trials (RCT) to inform the implementation of complex health interventions. This paper explores the learning accrued from conducting a PE within the Fa... Read More about Learning from a successful process evaluation in care homes.