All Outputs (1405)
Multiple groups of endogenous epsilon-like retroviruses conserved across primates (2014)
Journal Article
Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often describe... Read More about Multiple groups of endogenous epsilon-like retroviruses conserved across primates.
Highly sensitive detection of small ruminant bovine spongiform encephalopathy within transmissible spongiform encephalopathy mixes by serial protein misfolding cyclic amplification (2014)
Journal Article
It is assumed that sheep and goats consumed the same bovine spongiform encephalopathy (BSE)-contaminated meat and bone meal that was fed to cattle and precipitated the BSE epidemic in the United Kingdom that peaked more than 20 years ago. De- spite i... Read More about Highly sensitive detection of small ruminant bovine spongiform encephalopathy within transmissible spongiform encephalopathy mixes by serial protein misfolding cyclic amplification.
The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits (2014)
Journal Article
Alcelaphine herpesvirus-1 (AlHV-1) causes malignant catarrhal fever (MCF). The A2 gene of AlHV-1 is a member of the bZIP transcription factor family. We wished to determine whether A2 is a virulence gene or not and whether it is involved in pathogene... Read More about The A2 gene of alcelaphine herpesvirus-1 is a transcriptional regulator affecting cytotoxicity in virus-infected T cells but is not required for malignant catarrhal fever induction in rabbits.
Using simulation to interpret a discrete time survival model in a complex biological system: fertility and lameness in dairy cows (2014)
Journal Article
The ever-growing volume of data routinely collected and stored in everyday life presents researchers with a number of opportunities to gain insight and make predictions. This study aimed to demonstrate the usefulness in a specific clinical context of... Read More about Using simulation to interpret a discrete time survival model in a complex biological system: fertility and lameness in dairy cows.
Influenza A Virus Acquires Enhanced Pathogenicity and Transmissibility after Serial Passages in Swine (2014)
Journal Article
Genetic and phylogenetic analyses suggest that the pandemic H1N1/2009 virus was derived from well-established swine influenza lineages; however, there is no convincing evidence that the pandemic virus was generated from a direct precursor in pigs. Fu... Read More about Influenza A Virus Acquires Enhanced Pathogenicity and Transmissibility after Serial Passages in Swine.
Immediate early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the thoroughbred horse (2014)
Journal Article
Cytotoxic T-lymphocytes (CTLs) are associated with protective immunity against disease caused by equid herpesvirus type 1 (EHV-1). However, the EHV-1 target proteins for CTLs are poorly defined. This limits the development of vaccine candidates desig... Read More about Immediate early protein of equid herpesvirus type 1 as a target for cytotoxic T-lymphocytes in the thoroughbred horse.
Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development (2014)
Journal Article
This paper identifies a common nutritional pathway relating maternal through to fetal protein-energy malnutrition (PEM) and compromised fetal kidney development. Thirty-one twin-bearing sheep were fed either a control (n=15) or low-protein diet (n=16... Read More about Maternal protein-energy malnutrition during early pregnancy in sheep impacts the fetal ornithine cycle to reduce fetal kidney microvascular development.
Prevalence of Entamoeba species in captive primates in zoological gardens in the UK (2014)
Journal Article
The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology (2014)
Journal Article
1. Knowledge of species distribution is critical to ecological management and conservation biology. Effective management requires the detection of populations, which can sometimes be at low densities and is usually based on visual detection and count... Read More about The detection of aquatic animal species using environmental DNA – a review of eDNA as a survey tool in ecology.
A questionnaire-based survey on the uptake and use of cattle vaccines in the UK (2014)
Journal Article
Background: Vaccination is a widely used strategy for disease control in cattle in the UK and abroad. However, there has been limited research describing the uptake and use of cattle vaccines on UK farms. Aim: To describe the current uptake and usag... Read More about A questionnaire-based survey on the uptake and use of cattle vaccines in the UK.
Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations. (2014)
Journal Article
Changes to the DNA methylome have been described in patients with rheumatoid arthritis (RA). In previous work, we reported genome-wide methylation differences in T-lymphocyte and B-lymphocyte populations from healthy individuals. Now, using HumanMeth... Read More about Genome-wide DNA methylation profiling in rheumatoid arthritis identifies disease-associated methylation changes that are distinct to individual T- and B-lymphocyte populations..
Prospective survey of veterinary practitioners’ primary assessment of equine colic: clinical features, diagnoses, and treatment of 120 cases of large colon impaction (2014)
Journal Article
Background Large colon impactions are a common cause of colic in the horse. There are no scientific reports on the clinical presentation, diagnostic tests and treatments used in first opinion practice for large colon impaction cases. The aim of th... Read More about Prospective survey of veterinary practitioners’ primary assessment of equine colic: clinical features, diagnoses, and treatment of 120 cases of large colon impaction.
A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: assembly of the duck (Anas platyrhynchos) transcriptome (2014)
Journal Article
For vertebrate organisms where a reference genome is not available, de novo transcriptome assembly enables a cost effective insight into the identification of tissue specific or differentially expressed genes and variation of the coding part of the g... Read More about A consensus approach to vertebrate de novo transcriptome assembly from RNA-seq data: assembly of the duck (Anas platyrhynchos) transcriptome.
Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+?? T-cells are effective killers of protozoan parasites (2014)
Journal Article
IL-17 has emerged as a key player in the immune system, exhibiting roles in protection from infectious diseases and promoting inflammation in autoimmunity. Initially thought to be CD4 T-cell-derived, the sources of IL-17 are now known to be varied an... Read More about Two distinct populations of Bovine IL-17+ T-cells can be induced and WC1+IL-17+?? T-cells are effective killers of protozoan parasites.
Restoration of ovarian function and natural fertility following the cryopreservation and autotransplantation of whole adult sheep ovaries (2014)
Journal Article
study question: Is it possible to restore ovarian function and natural fertility following the cryopreservation and autotransplantation of whole ovaries, complete with vascular pedicle, in adult females from a large monovulatory animal model species... Read More about Restoration of ovarian function and natural fertility following the cryopreservation and autotransplantation of whole adult sheep ovaries.
SPACA3gene variants in a New Zealand cohort of infertile and fertile couples (2014)
Journal Article
SPRASA (also referred to as SLLP1) is a protein identified in the acrosome of human sperm and encoded by the gene SPACA3. SPRASA is associated with sperm-oocyte recognition and binding, and may play a role in fertility. In order to determine whether... Read More about SPACA3gene variants in a New Zealand cohort of infertile and fertile couples.
Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation (2014)
Journal Article
According to MEROPS peptidase database, Campylobacter species encode 64 predicted peptidases. However, proteolytic properties of only a few of these proteins have been confirmed experimentally. In this study we identified and characterised a Campylob... Read More about Campylobacter jejuni gene cj0511 encodes a serine peptidase essential for colonisation.
Use of wild bird surveillance, human case data and GIS spatial analysis for predicting spatial distributions of West Nile Virus in Greece (2014)
Journal Article
West Nile Virus (WNV) is the causative agent of a vector-borne, zoonotic disease with a worldwide distribution. Recent expansion and introduction of WNV into new areas, including southern Europe, has been associated with severe disease in humans and... Read More about Use of wild bird surveillance, human case data and GIS spatial analysis for predicting spatial distributions of West Nile Virus in Greece.
Characterisation of the horse transcriptome from immunologically active tissues (2014)
Journal Article
The immune system of the horse has not been well studied, despite the fact that the horse displays several features such as sensitivity to bacterial lipopolysaccharide that make them in many ways a more suitable model of some human disorders than the... Read More about Characterisation of the horse transcriptome from immunologically active tissues.