Characterisation of the horse transcriptome from immunologically active tissues
Moreton, Joanna; Malla, Sunir; Aboobaker, Aziz; Tarlinton, Rachael E.; Emes, Richard D.
Rachael E. Tarlinton
RICHARD EMES email@example.com
Professor of Bioinformatics
The immune system of the horse has not been well studied, despite the fact that the horse displays several features such as sensitivity to bacterial lipopolysaccharide that make them in many ways a more suitable model of some human disorders than the current rodent models. The difficulty of working with large animal models has however limited characterisation of gene expression in the horse immune system with current annotations for the equine genome restricted to predictions from other mammals and the few described horse proteins. This paper outlines sequencing of 184 million transcriptome short reads from immunologically active tissues of three horses including the genome reference “Twilight”. In a comparison with the Ensembl horse genome annotation, we found 8,763 potentially novel isoforms.
|Journal Article Type||Article|
|Publication Date||May 6, 2014|
|Peer Reviewed||Peer Reviewed|
|APA6 Citation||Moreton, J., Malla, S., Aboobaker, A., Tarlinton, R. E., & Emes, R. D. (2014). Characterisation of the horse transcriptome from immunologically active tissues. PeerJ, 2, https://doi.org/10.7717/peerj.382|
|Copyright Statement||Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0|
Copyright information regarding this work can be found at the following address: http://creativecommons.org/licenses/by/4.0
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