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Outputs (2377)

Yttrium-Enriched Phosphate Glass-Ceramic Microspheres for Bone Cancer Radiotherapy Treatment (2024)
Journal Article
Milborne, B., Arjuna, A., Islam, T., Arafat, A., Layfield, R., Thompson, A., & Ahmed, I. (in press). Yttrium-Enriched Phosphate Glass-Ceramic Microspheres for Bone Cancer Radiotherapy Treatment. Journal of the American Chemical Society,

This study presents the development and characterisation of high yttrium-content phosphate-based glass-ceramic microspheres for potential applications in bone cancer radiotherapy treatment. The microspheres produced via flame spheroidisa-tion, follow... Read More about Yttrium-Enriched Phosphate Glass-Ceramic Microspheres for Bone Cancer Radiotherapy Treatment.

Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways (2024)
Journal Article
Chukwuma Orji, O., Stones, J., Bagia, S., Markus, R., Demirbugen Öz, M., & Knight, H. (in press). Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways. Molecular Neurobiology,

N6 adenosine and C5 cytosine modification of mRNAs, tRNAs and rRNAs are regulated by the behaviour of distinct sets of writer, reader and eraser effector proteins which are conventionally considered to function independently. Here, we provide evidenc... Read More about Global co-regulatory cross talk between m6A and m5C RNA methylation systems coordinate cellular responses and brain disease pathways.

Exploiting phenotypic heterogeneity to improve production of glutathione by yeast (2024)
Journal Article
Xu, M., Vallières, C., Finnis, C., Winzer, K., & Avery, S. V. (2024). Exploiting phenotypic heterogeneity to improve production of glutathione by yeast. Microbial Cell Factories, 23, Article 267. https://doi.org/10.1186/s12934-024-02536-5

Background
Gene expression noise (variation in gene expression among individual cells of a genetically uniform cell population) can result in heterogenous metabolite production by industrial microorganisms, with cultures containing both low- and hig... Read More about Exploiting phenotypic heterogeneity to improve production of glutathione by yeast.

International review of blood donation screening for anti‐HBc and occult hepatitis B virus infection (2024)
Journal Article
Fu, M. X., Faddy, H. M., Candotti, D., Groves, J., Saa, P., Styles, C., Adesina, O., Perez Carrillo, J., Seltsam, A., Weber‐Schehl, M., O'Brien, S. F., Drews, S. J., Benyin Aidoo, N., Pajares, Á. L., Navarro Perez, L., Deng, X., van de Laar, T., Laperche, S., Lehtisalo, R., Yilmaz, S., …on behalf of the Virology subgroup of the ISBT WP-TTID. (2024). International review of blood donation screening for anti‐HBc and occult hepatitis B virus infection. Transfusion, https://doi.org/10.1111/trf.18018

Background
Hepatitis B core antibody (anti-HBc) screening has been implemented in many blood establishments to help prevent transmission of hepatitis B virus (HBV), including from donors with occult HBV infection (OBI). We review HBV screening algor... Read More about International review of blood donation screening for anti‐HBc and occult hepatitis B virus infection.

The expanding role of cap-adjacent modifications in animals (2024)
Journal Article
Bellows, E., Fray, R. G., Knight, H. M., & Archer, N. (2024). The expanding role of cap-adjacent modifications in animals. Frontiers in RNA Research, 2, Article 1485307. https://doi.org/10.3389/frnar.2024.1485307

Eukaryotic mRNA cap structures directly influence mRNA stability, translation, and immune recognition. While the significance of the mRNA cap itself has been well-established, recent research has revealed the intricate modifications to the nucleotide... Read More about The expanding role of cap-adjacent modifications in animals.

Sex Differences in Changes in Cardiorespiratory Fitness and Additional Health Outcomes Following Exercise Training in Adults With Atrial Fibrillation: A Systematic Review and Meta-Analysis. (2024)
Journal Article
Vidal-Almela, S., Marçal, I. R., Wong, J., Terada, T., Nguyen, B.-O., Joensen, A. M., Mills, M. T., Bittman, J., Prud'Homme, D., & Reed, J. L. (in press). Sex Differences in Changes in Cardiorespiratory Fitness and Additional Health Outcomes Following Exercise Training in Adults With Atrial Fibrillation: A Systematic Review and Meta-Analysis. Journal of Cardiopulmonary Rehabilitation and Prevention, 44(5), E52-E63. https://doi.org/10.1097/HCR.0000000000000891

Improving cardiorespiratory fitness (CRF) through exercise training is associated with lower morbidity and mortality in patients with atrial fibrillation (AF). Smaller CRF improvements have been suggested in females than males with cardiovascular dis... Read More about Sex Differences in Changes in Cardiorespiratory Fitness and Additional Health Outcomes Following Exercise Training in Adults With Atrial Fibrillation: A Systematic Review and Meta-Analysis..

Local cryptic diversity in salinity adaptation mechanisms in the wild outcrossing Brassica fruticulosa (2024)
Journal Article
Busoms, S., da Silva, A. C., Escolà, G., Abdilzadeh, R., Curran, E., Bollmann-Giolai, A., Bray, S., Wilson, M., Poschenrieder, C., & Yant, L. (2024). Local cryptic diversity in salinity adaptation mechanisms in the wild outcrossing Brassica fruticulosa. Proceedings of the National Academy of Sciences, 121(40), Article e2407821121. https://doi.org/10.1073/pnas.2407821121

It is normally supposed that populations of the same species should evolve shared mechanisms of adaptation to common stressors due to evolutionary constraint. Here, we describe a system of within-species local adaptation to coastal habitats, Brassica... Read More about Local cryptic diversity in salinity adaptation mechanisms in the wild outcrossing Brassica fruticulosa.

Discovery and Computational Modelling of Adsorbent Polymers that Effectively Immobilize SARS-CoV-2 with Potential Practical Applications (2024)
Journal Article
Xue, X., Duncan, J. D., Coleman, C. M., Contreas, L., Blackburn, C., Vivero-Lopez, M., Williams, P. M., Ball, J. K., Alexander, C., & Alexander, M. R. (2024). Discovery and Computational Modelling of Adsorbent Polymers that Effectively Immobilize SARS-CoV-2 with Potential Practical Applications. Cell Reports Physical Science, 5(9), Article 102204. https://doi.org/10.1016/j.xcrp.2024.102204

Viral translocation is considered a common way for respiratory viruses to spread and contaminate the surrounding environment. Thus, the discovery of non-eluting polymers that immobilize severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) upo... Read More about Discovery and Computational Modelling of Adsorbent Polymers that Effectively Immobilize SARS-CoV-2 with Potential Practical Applications.

Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice (2024)
Journal Article
Morgan, H. L., Eid, N., Holmes, N., Henson, S., Wright, V., Coveney, C., Winder, C., O’Neil, D. M., Dunn, W. B., Boocock, D. J., & Watkins, A. J. (2024). Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice. BMC Biology, 22, Article 207. https://doi.org/10.1186/s12915-024-01992-0

Background: The importance of parental diet in relation to eventual offspring health is increasing in prominence due to the increased frequency of parents of reproductive age consuming poor diets. Whilst maternal health and offspring outcome have bee... Read More about Paternal under and over nutrition modify semen composition and preimplantation embryo developmental kinetics in mice.