Skip to main content

Research Repository

Advanced Search

All Outputs (1393)

Exploiting heterogeneous environments: does photosynthetic acclimation optimize carbon gain in fluctuating light? (2015)
Journal Article

Plants have evolved complex mechanisms to balance the efficient use of absorbed light energy in photosynthesis with the capacity to use that energy in assimilation, so avoiding potential damage from excess light. This is particularly important under... Read More about Exploiting heterogeneous environments: does photosynthetic acclimation optimize carbon gain in fluctuating light?.

TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development (2015)
Journal Article

© 2015 Japa et al.; licensee BioMed Central. The helminth Fasciola hepatica causes fasciolosis throughout the world, a major disease of livestock and an emerging zoonotic disease in humans. Sustainable control mechanisms such as vaccination are urgen... Read More about TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development.

Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system (2015)
Journal Article

Normal placentation occurs under low oxygen tensions yet hypoxia is also implicated in placental pathologies such as pre-eclampsia (PE). Hypoxia-inducible factors (HIFs), adenosine and tissue renin-angiotensin-system (RAS) are known to promote angiog... Read More about Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system.

Animals and anomalies: an analysis of the UK veterinary profession and the relative lack of state reform (2015)
Journal Article

The sociology of professions literature would predict that the contemporary state would not allow groups to continue unregulated or unreformed. However, this is indeed the case with the UK veterinary profession, with legislation dating back to 1966.... Read More about Animals and anomalies: an analysis of the UK veterinary profession and the relative lack of state reform.

IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c (2015)
Journal Article

We show that IL-36? induced maturation of human MDDCs and stimulated differentiation of IFN-? producing (Type 1) CD3+ lymphocytes but was not as effective as IL-36? in doing so. For the first time, we also show that IL-36? induced expression of CD14... Read More about IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c.

The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses (2015)
Journal Article

PA-X is a novel protein encoded by PA mRNA and is found to decrease the pathogenicity of pandemic 1918 H1N1 virus in mice. However, the importance of PA-X proteins in current epidemiologically important influenza A virus strains is not known. In this... Read More about The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses.

Triaging informative cis-regulatory elements for the combinatorial control of temporal gene expression during Plasmodium falciparum intraerythrocytic development (2015)
Journal Article

Background: Over 2700 genes are subject to stage-specific regulation during the intraerythrocytic development of the human malaria parasite Plasmodium falciparum. Bioinformatic analyses have identified a large number of over-represented motifs in the... Read More about Triaging informative cis-regulatory elements for the combinatorial control of temporal gene expression during Plasmodium falciparum intraerythrocytic development.

Body composition and behaviour in adult rats are influenced by maternal diet, maternal age and high-fat feeding (2015)
Journal Article

Fetal exposure to maternal undernutrition has lifelong consequences for physiological and metabolic function. Maternal low-protein diet is associated with an age-related phenotype in rats, characterised by a period of resistance to development of obe... Read More about Body composition and behaviour in adult rats are influenced by maternal diet, maternal age and high-fat feeding.

Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis (2015)
Journal Article

Probabilistic sensitivity analysis (PSA) is a simulation-based technique for evaluating the relative importance of different inputs to a complex process model. It is commonly employed in decision analysis and for evaluation of the potential impact of... Read More about Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis.

Investigating common clinical presentations in first opinion small animal consultations using direct observation (2015)
Journal Article

Understanding more about the clinical presentations encountered in veterinary practice is vital in directing research towards areas relevant to practitioners. The aim of this study was to describe all problems discussed during a convenience sample of... Read More about Investigating common clinical presentations in first opinion small animal consultations using direct observation.