Skip to main content

Research Repository

Advanced Search

DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells

Kuchipudi, Suresh; Chang, Kin-Chow; Dunham, Stephen


Suresh Kuchipudi

Professor of Veterinary Molecular Medicine


The data described in this article pertain to the article by Kuchipudi et al. (2014) titled “Highly Pathogenic Avian Influenza Virus Infection in Chickens But Not Ducks Is Associated with Elevated Host Immune and Pro-inflammatory Responses” [1]. While infection of chickens with highly pathogenic avian influenza (HPAI) H5N1 virus subtypes often leads to 100% mortality within 1 to 2 days, infection of ducks in contrast causes mild or no clinical signs. The rapid onset of fatal disease in chickens, but with no evidence of severe clinical symptoms in ducks, suggests underlying differences in their innate immune mechanisms. We used Chicken Genechip microarrays (Affymetrix) to analyse the gene expression profiles of primary chicken and duck lung cells infected with a low pathogenic avian influenza (LPAI) H2N3 virus and two HPAI H5N1 virus subtypes to understand the molecular basis of host susceptibility and resistance in chickens and ducks. Here, we described the experimental design, quality control and analysis that were performed on the data set. The data are publicly available through the Gene Expression Omnibus (GEO)database with accession number GSE33389, and the analysis and interpretation of these data are included in Kuchipudi et al. (2014) [1].


Kuchipudi, S., Chang, K., & Dunham, S. (2015). DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells. Genomics Data, 4, 60-64.

Journal Article Type Article
Acceptance Date Mar 20, 2015
Online Publication Date Mar 20, 2015
Publication Date 2015-06
Deposit Date Jun 20, 2016
Print ISSN 2213-5960
Publisher Elsevier
Peer Reviewed Peer Reviewed
Volume 4
Pages 60-64
Public URL
Publisher URL