All Outputs (1390)

Youngstock Management as “The Key for Everything”? Perceived Value of Calves and the Role of Calf Performance Monitoring and Advice on Dairy Farms (2022)
Journal Article

Replacement heifers are key to the future milking herd and farm economic efficiency but are not always prioritised on dairy farms. Dairy enterprises are comprised of components which compete for limited resources; scarce information about calf perfor... Read More about Youngstock Management as “The Key for Everything”? Perceived Value of Calves and the Role of Calf Performance Monitoring and Advice on Dairy Farms.

Extracellular Vesicles Derived from Mesenchymal Stem Cells: Biological Activity and Approaches of Large-Scale Production (2022)
Book Chapter

The discovery of extracellular vesicles has provided an outstanding breakthrough in stem cells and regenerative medicine. It has been shown that cells can transfer information through the secretion of soluble factors, the formation of direct physical... Read More about Extracellular Vesicles Derived from Mesenchymal Stem Cells: Biological Activity and Approaches of Large-Scale Production.

Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases (2022)
Book Chapter

Mesenchymal stem cells (MSC) are specific cell types that enable tissue renewal within the body and are activated during the regeneration processes in response to injury. These cells are present in all human and animal tissues. In medical and biologi... Read More about Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases.

Extracellular vesicles and chronic obstructive pulmonary disease (COPD): a systematic review (2022)
Journal Article

Background: Chronic Obstructive Pulmonary Disease (COPD) is a common inflammatory disease of the airways characterized by irreversible airflow limitation, ranking the third highest cause of death worldwide. Extracellular vesicles (EVs) are important... Read More about Extracellular vesicles and chronic obstructive pulmonary disease (COPD): a systematic review.

Lipid biophysics and/or soft matter-inspired approach for controlling enveloped virus infectivity (2022)
Journal Article

Proven as a natural barrier against viral infection, pulmonary surfactant phospholipids have a biophysical and immunological role within the respiratory system, acting against microorganisms including viruses. Enveloped viruses have, in common, an ou... Read More about Lipid biophysics and/or soft matter-inspired approach for controlling enveloped virus infectivity.

Repeatability and Predictability of Calf Feeding Behaviors—Quantifying Between- and Within-Individual Variation for Precision Livestock Farming (2022)
Journal Article

Individual calves show substantial between- and within-individual variation in their feeding behavior, the existence and extent of which are not fully researched. In this study, 57,196 feeding records, collected by a computerized milk feeder from 48... Read More about Repeatability and Predictability of Calf Feeding Behaviors—Quantifying Between- and Within-Individual Variation for Precision Livestock Farming.

How can mating systems inform future biobanking strategies? An illustration using two Indonesian bovids, banteng (Bos javanicus) and lowland anoa (Bubalus depressicornis) (2022)
Journal Article

Storing cryopreserved spermatozoa in a genome resource bank safeguards against the loss of heterozygosity in endangered species and provides opportunities to reincorporate genes into populations through the application of assisted reproductive techno... Read More about How can mating systems inform future biobanking strategies? An illustration using two Indonesian bovids, banteng (Bos javanicus) and lowland anoa (Bubalus depressicornis).

Gene Expression Profile Induced by Two Different Variants of Street Rabies Virus in Mice (2022)
Journal Article

Pathogenicity and pathology of rabies virus (RABV) varies according to the variant, but the mechanisms are not completely known. In this study, gene expression profile in brains of mice experimentally infected with RABV isolated from a human case of... Read More about Gene Expression Profile Induced by Two Different Variants of Street Rabies Virus in Mice.

PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer (2022)
Journal Article

PIP5K1α has emerged as a promising drug target for the treatment of castration-resistant prostate cancer (CRPC), as it acts upstream of the PI3K/AKT signaling pathway to promote prostate cancer (PCa) growth, survival and invasion. However, little is... Read More about PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer.

Cardiovascular and locomotory parameters during training in Thoroughbred racehorses: a multi-national study (2022)
Journal Article

Studies assessing concurrent speed, cardiovascular physiology and biomechanical parameters in racehorses during training have been rarely reported, mostly due to a lack of available comprehensive technology. Here, using a validated device (the ‘Equim... Read More about Cardiovascular and locomotory parameters during training in Thoroughbred racehorses: a multi-national study.

Viral Vector Vaccines Against ASF: Problems and Prospectives (2022)
Journal Article

African swine fever (ASF) is a highly contagious viral disease affecting pigs, with mortality rates a primary focus as they can reach up to 100%. The widespread and colossal economic losses from ASF have impacts on the development of animal husbandry... Read More about Viral Vector Vaccines Against ASF: Problems and Prospectives.

A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour (2022)
Journal Article

As a global society, we have a duty to provide suitable care and conditions for farmed livestock to protect animal welfare and ensure the sustainability of our food supply. The suitability and biological impacts of housing conditions for intensively... Read More about A randomised controlled trial to evaluate the impact of indoor living space on dairy cow production, reproduction and behaviour.

CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses (2022)
Journal Article

Cap-adjacent nucleotides of animal, protist and viral mRNAs can be O-methylated at the 2`position of the ribose (cOMe). The functions of cOMe in animals, however, remain largely unknown. Here we show that the two cap methyltransferases (CMTr1 and CMT... Read More about CMTr cap-adjacent 2′-O-ribose mRNA methyltransferases are required for reward learning and mRNA localization to synapses.

Searching for veterinary evidence: A guide for equine professionals (2022)
Journal Article

There is more and more online information available at our fingertips, but how do we efficiently identify and extract relevant information for good clinical decision making? The aim of this review article is to provide equine professionals with the b... Read More about Searching for veterinary evidence: A guide for equine professionals.

Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP (2022)
Journal Article

Our cluster analysis of the Cancer Genome Atlas for co-expression of HSP27 and CRYAB in breast cancer patients identified three patient groups based on their expression level combination (high HSP27 + low CRYAB; low HSP27 + high CRYAB; similar HSP27 ... Read More about Cluster analyses of the TCGA and a TMA dataset using the coexpression of HSP27 and CRYAB improves alignment with clinical-pathological parameters of breast cancer and suggests different epichaperome influences for each sHSP.

The importance of preventative healthcare: what 10 years of research from the Centre for Evidence-based Veterinary Medicine reveals (2022)
Journal Article

Two zinc finger proteins with functions in m6A writing interact with HAKAI (2022)
Journal Article

The methyltransferase complex (m6A writer), which catalyzes the deposition of N6-methyladenosine (m6A) in mRNAs, is highly conserved across most eukaryotic organisms, but its components and interactions between them are still far from fully understoo... Read More about Two zinc finger proteins with functions in m6A writing interact with HAKAI.

Whole-genome sequencing and gene sharing network analysis powered by machine learning identifies antibiotic resistance sharing between animals, humans and environment in livestock farming (2022)
Journal Article

Anthropogenic environments such as those created by intensive farming of livestock, have been proposed to provide ideal selection pressure for the emergence of antimicrobial-resistant Escherichia coli bacteria and antimicrobial resistance genes (ARGs... Read More about Whole-genome sequencing and gene sharing network analysis powered by machine learning identifies antibiotic resistance sharing between animals, humans and environment in livestock farming.

Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry (2022)
Journal Article

Viral diseases, including avian influenza (AI) and Newcastle disease (ND), are an important cause of morbidity and mortality in poultry, resulting in significant economic losses. Despite the availability of commercial vaccines for the major viral dis... Read More about Development of Plant-Based Vaccines for Prevention of Avian Influenza and Newcastle Disease in Poultry.

Illuminating Host-Parasite Interaction at the Cellular and Subcellular Levels with Infrared Microspectroscopy (2022)
Journal Article

Toxoplasma gondii (T. gondii) is an opportunistic protozoan that can cause brain infection and other serious health consequences in immuno-compromised individuals. This parasite has a remarkable ability to cross biological barriers and exploit the ho... Read More about Illuminating Host-Parasite Interaction at the Cellular and Subcellular Levels with Infrared Microspectroscopy.