All Outputs (125)

Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus (2021)
Journal Article

Four undescribed cucurbitacins, designated as petiolaticins A–D, and four known cucurbitacins were isolated from the bark and leaves of Elaeocarpus petiolatus (Jack) Wall. Their chemical structures were elucidated based on detailed analyses of the NM... Read More about Pentacyclic and hexacyclic cucurbitacins from Elaeocarpus petiolatus.

A scoping review of the current evidence on treatment and outcomes following synovial sepsis (2021)
Journal Article

Background Synovial sepsis is a frequent cause of morbidity and mortality in horses. Despite advances in diagnostics and treatments, persistent infection or chronic lameness can occur. Objectives To perform a scoping review to identify and evalu... Read More about A scoping review of the current evidence on treatment and outcomes following synovial sepsis.

Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex (2021)
Journal Article

Ageing is a major risk factor for many of the most prevalent diseases, including neurode-generative diseases, cancer, and heart disease. As the global population continues to age, behavioural interventions that can promote healthy ageing will improve... Read More about Exercising D. melanogaster Modulates the Mitochondrial Proteome and Physiology. The Effect on Lifespan Depends upon Age and Sex.

Biosecurity and the ornamental fish trade: A stakeholder perspective in England (2021)
Journal Article

The freshwater and marine ornamental fish industry is a primary route of hazard introduction and emergence, including aquatic animal diseases and non-native species. Prevention measures are key to reducing the risk of hazard incursion and establishme... Read More about Biosecurity and the ornamental fish trade: A stakeholder perspective in England.

Genetics of Asthma: Insights From Genome Wide Association Studies (2021)
Book Chapter

Asthma is a heterogeneous respiratory disease that can be influenced by genetic and environmental factors leading to disease susceptibility and progression. Genome-wide association studies (GWAS) of asthma have yielded replicated findings and identif... Read More about Genetics of Asthma: Insights From Genome Wide Association Studies.

Pharmacokinetics of paracetamol in the Thoroughbred horse following an oral multi-dose administration (2021)
Journal Article

Paracetamol is a widely used, non-opioid analgesic and antipyretic drug. Scientific evidence suggests that it is an effective pain treatment in equine medicine. However, there is very little published information about the pharmacokinetics of the dru... Read More about Pharmacokinetics of paracetamol in the Thoroughbred horse following an oral multi-dose administration.

Comparative pathology of dog and human prostate cancer (2021)
Journal Article

Though relatively rare in dogs, prostate cancer (PCa) is the most common non-cutaneous cancer in men. Human and canine prostate glands share many functional, anatomical and physiological features. Due to these similarities, canine PCa has been propos... Read More about Comparative pathology of dog and human prostate cancer.

Does using an endotracheal tube or a supraglottic airway device result in better unassisted ventilation in rabbits? (2021)
Journal Article

Sequence and structure comparison of ATP synthase F0 subunits 6 and 8 in notothenioid fish (2021)
Journal Article

Mitochondrial changes such as tight coupling of the mitochondria have facilitated sustained oxygen and respiratory activity in haemoglobin-less icefish of the Channichthyidae family. We aimed to characterise features in the sequence and structure of... Read More about Sequence and structure comparison of ATP synthase F0 subunits 6 and 8 in notothenioid fish.

Extracellular vesicles, tumor growth, and the metastatic process (2021)
Book Chapter

Extracellular vesicles (EVs) form an important part of cell-to-cell communication, with roles in both health and disease. Within the cancer setting, this heterogenous population of extracellular messengers can have both pro- and antitumorigenic prope... Read More about Extracellular vesicles, tumor growth, and the metastatic process.

Stakeholder Perceptions of Disease Management for Dairy Calves: “It’s Just Little Things That Make Such a Big Difference” (2021)
Journal Article

Calf morbidity and mortality rates are often high in dairy herds, raising animal welfare concerns and negatively affecting farm economic efficiency and future performance. Disease prevention is critical to maintain calves in good health, but interven... Read More about Stakeholder Perceptions of Disease Management for Dairy Calves: “It’s Just Little Things That Make Such a Big Difference”.

Waterborne protozoan outbreaks: An update on the global, regional, and national prevalence from 2017 to 2020 and sources of contamination (2021)
Journal Article

The aim of this review is to identify the worldwide trend of waterborne protozoan outbreaks and how it varies between geographic regions during the period from 2017 to 2020. Data about waterborne protozoan outbreaks were gathered and stratified by co... Read More about Waterborne protozoan outbreaks: An update on the global, regional, and national prevalence from 2017 to 2020 and sources of contamination.

Recent Advances in Experimental Dendritic Cell Vaccines for Cancer (2021)
Journal Article

The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies. There was no breakthrough after first using of personalized therapeutic vaccines based on... Read More about Recent Advances in Experimental Dendritic Cell Vaccines for Cancer.

Assessment of proliferation in breast cancer: cell cycle or mitosis? An observational study (2021)
Journal Article

Background and aims: Proliferation is an important indicator of breast cancer (BC) prognosis, but is assessed using different approaches. Not all cells in the cell cycle are committed to division. This study aimed to characterise quantitative differe... Read More about Assessment of proliferation in breast cancer: cell cycle or mitosis? An observational study.

Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection (2021)
Journal Article

The canine epigastric organs, their locations and visualization of these components are essential for veterinary practice and anatomical research. Despite their importance, conflicts and discrepancies in the published material, to date, still exist,... Read More about Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection.

Extracellular Vesicles and Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review (2021)
Working Paper

Background: Chronic Obstructive Pulmonary Disease (COPD) is a common inflammatory disease of the airways characterized by irreversible airflow limitation, ranking the third highest cause of death worldwide. Extracellular vesicles (EVs) are important... Read More about Extracellular Vesicles and Chronic Obstructive Pulmonary Disease (COPD): A Systematic Review.

Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses (2021)
Journal Article

Hydroxyzine and cetirizine are first- and second-generation oral antihistamine drugs, respectively, used to treat allergic reactions in horses. Cetirizine is also a metabolite of hydroxyzine, which may lead to complexities in regulating their use in... Read More about Plasma and urine pharmacokinetics of hydroxyzine and cetirizine following repeated oral administrations to exercised horses.

Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties (2021)
Journal Article

Low-power sonication is widely used to disaggregate extracellular vesicles (EVs) after isolation, however, the effects of sonication on EV samples beyond dispersion are unclear. The present study analysed the characteristics of EVs collected from mes... Read More about Low-Power Sonication Can Alter Extracellular Vesicle Size and Properties.

Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK (2021)
Journal Article

Objectives Bacterial urinary tract infections are a common diagnosis in small animal practice and antibiotics are often administered empirically. The aim of this study was to investigate the aetiology and antibiotic resistance of uropathogens in dog... Read More about Results of urinary bacterial cultures and antibiotic susceptibility testing of dogs and cats in the UK.

Assessment of health and welfare in a small sample of dogs owned by people who are homeless (2021)
Journal Article

Background: Pet ownership is common among homeless people, with dogs the most frequently reported pets. However, homeless people receive considerable criticism for keeping pets due to public perception of poor care provision. Materials and methods: A... Read More about Assessment of health and welfare in a small sample of dogs owned by people who are homeless.