All Outputs (139)

An investigation into the clinical reasoning development of veterinary students (2016)
Journal Article
Vinten, C., Cobb, K. A., Freeman, S., & Mossop, L. (in press). An investigation into the clinical reasoning development of veterinary students. Journal of Veterinary Medical Education, 43(4), https://doi.org/10.3138/jvme.0815-130R1

Clinical reasoning is a fundamental skill for veterinary clinicians and a competency required of graduates by the Royal College of Veterinary Surgeons. However, it is unknown how veterinary students develop reasoning skills and where strengths and sh... Read More about An investigation into the clinical reasoning development of veterinary students.

Structure of a low-population binding intermediate in protein-RNA recognition (2016)
Journal Article
Borkar, A. N., Bardaro, M. F., Camilloni, C., Aprile, F. A., Varani, G., & Vendruscolo, M. (2016). Structure of a low-population binding intermediate in protein-RNA recognition. Proceedings of the National Academy of Sciences, 113(26), 7171-7176. https://doi.org/10.1073/pnas.1521349113

All biochemical reactions in living organisms require molecular recognition events. In particular, the interactions between protein and RNA molecules are crucial in the regulation of gene expression. However, the transient nature of the conformations... Read More about Structure of a low-population binding intermediate in protein-RNA recognition.

The influence of peri-conception and first trimester dietary restriction of protein in cattle on meat quality traits of entire male progeny (2016)
Journal Article
Alvarenga, T. I., Copping, K. J., Han, X., Clayton, E. H., Meyer, R. J., Rodgers, R. J., …Geesink, G. (in press). The influence of peri-conception and first trimester dietary restriction of protein in cattle on meat quality traits of entire male progeny. Meat Science, 121, https://doi.org/10.1016/j.meatsci.2016.06.006

Primiparous Santa Gertrudis heifers were used to evaluate the effects of gestational dietary protein content on meat quality traits of 20 month old bull progeny (n = 40). At ? 60 d before AI, heifers were randomly allocated to HIGH or LOW protein die... Read More about The influence of peri-conception and first trimester dietary restriction of protein in cattle on meat quality traits of entire male progeny.

IL-36 receptor is expressed by human blood and intestinal T lymphocytes and is dose–dependently activated via IL-36β and induces CD4+ lymphocyte proliferation (2016)
Journal Article
Penha, R., Higgins, J., Mutamba, S., Barrow, P., Mahida, Y. R., & Foster, N. (2016). IL-36 receptor is expressed by human blood and intestinal T lymphocytes and is dose–dependently activated via IL-36β and induces CD4+ lymphocyte proliferation. Cytokine, 85, https://doi.org/10.1016/j.cyto.2016.05.023

We show that IL-36R is expressed by T (CD4+ and CD8+) and B (CD19+) lymphocytes in human blood and also by CD4+ T lymphocytes in the intestinal lamina propria. IL-36R protein was mostly stored in the cytoplasm of CD4 lymphocytes and B cells, during s... Read More about IL-36 receptor is expressed by human blood and intestinal T lymphocytes and is dose–dependently activated via IL-36β and induces CD4+ lymphocyte proliferation.

Broken biosecurity?: veterinarians’ framing of biosecurity on dairy farms in England (2016)
Journal Article
Shortall, O., Ruston, A., Green, M. J., Brennan, M. L., Wapenaar, W., & Kaler, J. (2016). Broken biosecurity?: veterinarians’ framing of biosecurity on dairy farms in England. Preventive Veterinary Medicine, 132, https://doi.org/10.1016/j.prevetmed.2016.06.001

There is seen to be a need for better biosecurity – the control of disease spread on and off farm – in the dairy sector. Veterinarians play a key role in communicating and implementing biosecurity measures on farm, and little research has been carrie... Read More about Broken biosecurity?: veterinarians’ framing of biosecurity on dairy farms in England.

Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs (2016)
Journal Article
Kong, W., Liu, Q., Sun, Y., Wang, Y., Gao, H., Liu, L., …Liu, J. (2016). Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs. Scientific Reports, 6, Article 27067. https://doi.org/10.1038/srep27067

Given the present extensive co-circulation in pigs of Eurasian avian-like (EA) swine H1N1 and 2009 pandemic (pdm/09) H1N1 viruses, reassortment between them is highly plausible but largely uncharacterized. Here, experimentally co-infected pigs with a... Read More about Transmission and pathogenicity of novel reassortants derived from Eurasian avian-like and 2009 pandemic H1N1 influenza viruses in mice and guinea pigs.

Association of Aromatase With Bladder Cancer Stage and Long-Term Survival: New Insights Into the Hormonal Paradigm in Bladder Cancer (2016)
Journal Article
Nguyen, D. P., O'Malley, P., Al Hussein Al Awamlh, B., Furrer, M., Mongan, N. P., Robinson, B. D., …Scherr, D. S. (2017). Association of Aromatase With Bladder Cancer Stage and Long-Term Survival: New Insights Into the Hormonal Paradigm in Bladder Cancer. Clinical Genitourinary Cancer, 15(2), 256-262.e1. https://doi.org/10.1016/j.clgc.2016.05.017

BACKGROUND Hormonal factors may play a role in bladder cancer (BCa). We investigated the expression of aromatase and estrogen receptor (ER)β and its association with pathological variables and survival outcomes. PATIENTS AND METHODS BCa spec... Read More about Association of Aromatase With Bladder Cancer Stage and Long-Term Survival: New Insights Into the Hormonal Paradigm in Bladder Cancer.

Evidence of Mycobacterium tuberculosis Complex bacteraemia in intradermal skin test positive cattle detected using phage-RPA (2016)
Journal Article
Swift, B., Convery, T., & Rees, C. (2016). Evidence of Mycobacterium tuberculosis Complex bacteraemia in intradermal skin test positive cattle detected using phage-RPA. Virulence, 7(7), 779-788. https://doi.org/10.1080/21505594.2016.1191729

Bovine tuberculosis is a zoonotic infectious disease caused by Mycobacterium bovis 19 that affects cattle and can cause tuberculosis in a range of wildlife animals. A 20 bacteriophage-based method combined with PCR (phage-PCR) has been recently used... Read More about Evidence of Mycobacterium tuberculosis Complex bacteraemia in intradermal skin test positive cattle detected using phage-RPA.

?-chloralose poisoning in a cat (2016)
Journal Article
Grau-Roma, L., Stephens, A., Wessmann, A., Carmichael, N., & de Brot, S. (2016). ?-chloralose poisoning in a cat. Vet Record Case Reports, 4(e00031), https://doi.org/10.1136/vetreccr-2016-000313

A five-year-old domestic cat with acute unexplainable neurological signs was presented for postmortem examination. Clinically, the cat showed an acute onset of ataxia, depressed mentation and continuous twitching/ seizure activity in the morning afte... Read More about ?-chloralose poisoning in a cat.

Experimental infection of chickens by a flagellated motile strain of Salmonella enterica serovar Gallinarum biovar Gallinarum (2016)
Journal Article
Lopes, P., Freitas Neto, O., Batista, D., Denadai, J., Alarcon, M., Almeida, A., …Berchieri, A. (2016). Experimental infection of chickens by a flagellated motile strain of Salmonella enterica serovar Gallinarum biovar Gallinarum. Veterinary Journal, 214, https://doi.org/10.1016/j.tvjl.2016.05.006

Salmonella enterica subsp. enterica serovar Gallinarum biovar Gallinarum (SG) causes fowl typhoid (FT), a septicaemic disease which can result in high mortality in poultry flocks. The absence of flagella in SG is thought to favour systemic invasion,... Read More about Experimental infection of chickens by a flagellated motile strain of Salmonella enterica serovar Gallinarum biovar Gallinarum.

Analysis of mitochondrial haemoglobin in Parkinson's disease brain (2016)
Journal Article
Shephard, F., Greville-Heygate, O., Liddell, S., Emes, R. D., & Chakrabarti, L. (2016). Analysis of mitochondrial haemoglobin in Parkinson's disease brain. Mitochondrion, 29, 45-52. https://doi.org/10.1016/j.mito.2016.05.001

Mitochondrial dysfunction is an early feature of neurodegeneration. We have shown there are mitochondrial haemoglobin changes with age and neurodegeneration. We hypothesised that altered physiological processes are associated with recruitment and loc... Read More about Analysis of mitochondrial haemoglobin in Parkinson's disease brain.

Combination of competitive exclusion and immunisation with a live Salmonella vaccine in newly hatched chickens: immunological and microbiological effects (2016)
Journal Article
Braukmann, M., Barrow, P., Berndt, A., & Methner, U. (2016). Combination of competitive exclusion and immunisation with a live Salmonella vaccine in newly hatched chickens: immunological and microbiological effects. Research in Veterinary Science, 107, https://doi.org/10.1016/j.rvsc.2016.05.001

In addition to evaluating the efficacy potential of a combined use of vaccination and competitive exclusion (CE) against Salmonella exposure in chicks at 3-days of age, a live Salmonella Enteritidis vaccine (SE-LV) and a CE culture were tested for th... Read More about Combination of competitive exclusion and immunisation with a live Salmonella vaccine in newly hatched chickens: immunological and microbiological effects.

The association between age at first calving and survival of first lactation heifers within dairy herds (2016)
Journal Article
Sherwin, V., Hudson, C., Henderson, A., & Green, M. J. (2016). The association between age at first calving and survival of first lactation heifers within dairy herds. animal, 10(11), https://doi.org/10.1017/S1751731116000689

The objective of this research was to evaluate the survival rate of primiparous heifers within a large sample of herds across the UK and specifically to assess the association between age at first calving (AFC) on their survival. Data from 437 herds... Read More about The association between age at first calving and survival of first lactation heifers within dairy herds.

Six-year follow-up of slaughterhouse surveillance (2008-2013): the Catalan Slaughterhouse Support Network (SESC) (2016)
Journal Article
Vidal, E., Tolosa, E., Espinar, S., Pérez de Va, B., Nofrarías, M., Alba, A., …Domingo, M. (2016). Six-year follow-up of slaughterhouse surveillance (2008-2013): the Catalan Slaughterhouse Support Network (SESC). Veterinary Pathology, 53(3), https://doi.org/10.1177/0300985815593125

Meat inspection has the ultimate objective of declaring the meat and offal obtained from carcasses of slaughtered animals fit or unfit for human consumption. This safeguards the health of consumers by ensuring that the food coming from these establis... Read More about Six-year follow-up of slaughterhouse surveillance (2008-2013): the Catalan Slaughterhouse Support Network (SESC).

Health knowledge and infection control by event horse owners (2016)
Journal Article
Ellis, H., Kendall, N. R., & Kydd, J. H. (2016). Health knowledge and infection control by event horse owners. Journal of Equine Veterinary Science, 39(Supplement), S4-S5. https://doi.org/10.1016/j.jevs.2016.02.009

Infection control and quarantine measures are essential to minimise the impact of equine infectious diseases, but their uptake by equestrians involved with sport horses in the United Kingdom is undocumented. Using a questionnaire, this study aimed to... Read More about Health knowledge and infection control by event horse owners.

Canine ovariohysterectomy: a survey of surgeon concerns and surgical complications encountered by newly graduated veterinarians (2016)
Journal Article
Blacklock, K. L. B., Langer, P., Halfacree, Z., Yool, D. A., Corr, S., Owen, L., …Ekiri, A. (2016). Canine ovariohysterectomy: a survey of surgeon concerns and surgical complications encountered by newly graduated veterinarians. Journal of Veterinary Medical Education, 43(2), https://doi.org/10.3138/jvme.0915-147R

The objective of this study was to document newly qualified veterinarians’ concerns and surgical complications encountered during canine ovariohysterectomy (cOVH) during the first year of general practice. A questionnaire investigating concerns about... Read More about Canine ovariohysterectomy: a survey of surgeon concerns and surgical complications encountered by newly graduated veterinarians.

The ecology of wildlife disease surveillance: demographic and prevalence fluctuations undermine surveillance (2016)
Journal Article
Walton, L., Marion, G., Davidson, R. S., White, P. C., Smith, L. A., Gavier-Widen, D., …Hutchings, M. R. (2016). The ecology of wildlife disease surveillance: demographic and prevalence fluctuations undermine surveillance. Journal of Applied Ecology, 53(5), 1460-1469. https://doi.org/10.1111/1365-2664.12671

1. Wildlife disease surveillance is the first line of defence against infectious disease. Fluctuations in host populations and disease prevalence are a known feature of wildlife disease systems. However, the impact of such heterogeneities on the per... Read More about The ecology of wildlife disease surveillance: demographic and prevalence fluctuations undermine surveillance.

Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia (2016)
Journal Article
Parry, H. M., Damery, S., Hudson, C., Maurer, M. J., Cerhan, J. R., Pachnio, A., …Moss, P. A. (2016). Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia. American Journal of Hematology, 91(8), https://doi.org/10.1002/ajh.24403

Human cytomegalovirus (HCMV) is a widely prevalent herpes virus which establishes a state of chronic infection. The establishment of CMV-specific immunity controls viral reactivation and leads to the accumulation of very large numbers of virus-specif... Read More about Cytomegalovirus infection does not impact on survival or time to first treatment in patients with chronic lymphocytic leukemia.

Bayesian estimation of prevalence of paratuberculosis in dairy herds enrolled in a voluntary Johne’s Disease Control Programme in Ireland (2016)
Journal Article
McAloon, C. G., Doherty, M. L., Whyte, P., O’Grady, L., More, S. J., Messam, L. L. M., …Green, M. J. (2016). Bayesian estimation of prevalence of paratuberculosis in dairy herds enrolled in a voluntary Johne’s Disease Control Programme in Ireland. Preventive Veterinary Medicine, 128, https://doi.org/10.1016/j.prevetmed.2016.04.014

Bovine paratuberculosis is a disease characterised by chronic granulomatous enteritis which manifests clinically as a protein-losing enteropathy causing diarrhoea, hypoproteinaemia, emaciation and, eventually death. Some evidence exists to suggest a... Read More about Bayesian estimation of prevalence of paratuberculosis in dairy herds enrolled in a voluntary Johne’s Disease Control Programme in Ireland.

Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets (2016)
Journal Article
Sun, H., Pu, J., Wei, Y., Sun, Y., Hu, J., Liu, L., …Liu, J. (2016). Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets. Journal of Virology, 90(14), https://doi.org/10.1128/JVI.00127-16

Since May 2014, highly pathogenic avian influenza H5N6 virus has been reported to cause six severe human infections three of which were fatal. The biological properties of this subtype, in particular its relative pathogenicity and transmissibility in... Read More about Highly pathogenic avian influenza H5N6 viruses exhibit enhanced affinity for human type sialic acid receptor and in-contact transmission in model ferrets.