All Outputs (1324)

Exploring the responses of smallscale poultry keepers to avian influenza regulations and guidance in the United Kingdom, with recommendations for improved biosecurity messaging (2023)
Journal Article
Jewitt, S., Smallman-Raynor, M., McClaughlin, E., Clark, M., Dunham, S., Elliott, S., …Tarlinton, R. (2023). Exploring the responses of smallscale poultry keepers to avian influenza regulations and guidance in the United Kingdom, with recommendations for improved biosecurity messaging. Heliyon, 9(9), Article E19211. https://doi.org/10.1016/j.heliyon.2023.e19211

Understanding how smallscale (‘backyard’) poultry keepers interpret and respond to governmental directives designed to reduce the transmission of highly pathogenic avian influenza (HPAI) is of paramount importance in preparing for future HPAI outbrea... Read More about Exploring the responses of smallscale poultry keepers to avian influenza regulations and guidance in the United Kingdom, with recommendations for improved biosecurity messaging.

Immune responses to Tilapia lake virus infection: what we know and what we don't know (2023)
Journal Article
Kembou-Ringert, J. E., Steinhagen, D., Thompson, K. D., Daly, J. M., & Adamek, M. (2023). Immune responses to Tilapia lake virus infection: what we know and what we don't know. Frontiers in Immunology, 14, Article 1240094. https://doi.org/10.3389/fimmu.2023.1240094

Tilapia lake virus (TiLV) is a novel contagious pathogen associated with a lethal disease affecting and decimating tilapia populations on several continents across the globe. Fish viral diseases, such as Tilapia lake virus disease (TiLVD), represent... Read More about Immune responses to Tilapia lake virus infection: what we know and what we don't know.

Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance (2023)
Journal Article
Panner Selvam, M. K., Kanagaraj, V., Kathaperumal, K., Nissly, R. H., Daly, J. M., & Kuchipudi, S. V. (2023). Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance. VirusDisease, 34(3), 402-409. https://doi.org/10.1007/s13337-023-00833-y

Newcastle disease (ND) affects a few hundred avian species including chicken and several species of domestic and wild birds. The clinical outcome of Newcastle disease virus (NDV) infection ranges from mild to severe fatal disease depending on the NDV... Read More about Comparative transcriptome analysis of spleen of Newcastle Disease Virus (NDV) infected chicken and Japanese quail: a potential role of NF-κβ pathway activation in NDV resistance.

Predicting lameness in dairy cattle using untargeted liquid chromatography–mass spectrometry-based metabolomics and machine learning (2023)
Journal Article
Randall, L. V., Kim, D., Abdelrazig, S. M., Bollard, N. J., Hemingway-Arnold, H., Hyde, R. M., …Green, M. J. (2023). Predicting lameness in dairy cattle using untargeted liquid chromatography–mass spectrometry-based metabolomics and machine learning. Journal of Dairy Science, 106(10), 7033-7042. https://doi.org/10.3168/jds.2022-23118

Lameness in dairy cattle is a highly prevalent condition that impacts on the health and welfare of dairy cows. Prompt detection and implementation of effective treatment is important for managing lameness. However, major limitations are associated wi... Read More about Predicting lameness in dairy cattle using untargeted liquid chromatography–mass spectrometry-based metabolomics and machine learning.

A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer (2023)
Journal Article
Ebanks, B., Kwiecinska, P., Moisoi, N., & Chakrabarti, L. (2023). A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer. PLoS ONE, 18(7), Article e0276147. https://doi.org/10.1371/journal.pone.0276147

High-resolution respirometry methods allow for the assessment of oxygen consumption by the electron transfer systems within cells, tissue samples, and isolated mitochondrial preparations. As mitochondrial integrity is compromised by the process of cr... Read More about A method to assess the mitochondrial respiratory capacity of complexes I and II from frozen tissue using the Oroboros O2k-FluoRespirometer.

Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches (2023)
Journal Article
Moxon, R., Dutton Worsfold, R., Davis, J., Adams, W., & England, G. C. W. (2023). Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches. Veterinary Medicine and Science, https://doi.org/10.1002/vms3.1195

Objectives: To establish packed cell volume (PCV) ranges for non‐pregnant, pregnant and post‐partum bitches from day 10 of proestrus, investigating any relationship with parity and litter size. Methods: This prospective cohort study used 37 healthy b... Read More about Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches.

The clinical and biological significance of estrogen receptor-low positive breast cancer (2023)
Journal Article
Makhlouf, S., Althobi, M., Toss, M., Muftah, A. A., Mongan, N. P., Lee, A. H. S., …Rakha, E. A. (2023). The clinical and biological significance of estrogen receptor-low positive breast cancer. Modern Pathology, 36(10), Article 100284. https://doi.org/10.1016/j.modpat.2023.100284

Estrogen Receptor (ER) status in breast cancer (BC) is determined using immunohistochemistry (IHC) with nuclear expression in ≥1% of cells defined as ER-positive. BC with 1-9% expression (ER-low positive), is a clinically and biologically unique subg... Read More about The clinical and biological significance of estrogen receptor-low positive breast cancer.

Anatomical oropharyngeal cavity specialisations in the cutlassfish (Trichiurus lepturus, Linnaeus, 1758) (2023)
Journal Article
El-Bakary, N. E., Alsafy, M. A., Rutland, C. S., El-Gendy, S. A., & Kamal, B. M. (2023). Anatomical oropharyngeal cavity specialisations in the cutlassfish (Trichiurus lepturus, Linnaeus, 1758). Anatomia, Histologia, Embryologia, 52(6), 821-1033. https://doi.org/10.1111/ahe.12943

Trichiurus lepturus is a carnivorous fish, and most of the previous anatomical research has focused on computed tomography imaging and histology of their teeth and fangs, while the remaining structures of pharyngeal cavity remain unexplored. The pres... Read More about Anatomical oropharyngeal cavity specialisations in the cutlassfish (Trichiurus lepturus, Linnaeus, 1758).

Advances in the understanding, detection and management of equine strangles (2023)
Journal Article
McLinden, L. A., Freeman, S. L., Daly, J., Blanchard, A., Kemp‐Symonds, J. G., & Waller, A. (2023). Advances in the understanding, detection and management of equine strangles. Equine Veterinary Education, 35(12), 662-672. https://doi.org/10.1111/eve.13845

Streptococcus equi subspecies equi (S. equi) is the causative organism of the upper respiratory disease of equids, strangles, characterised by pyrexia, lymphadenopathy and mucopurulent nasal discharge. Strangles was first reported over 750 years ago... Read More about Advances in the understanding, detection and management of equine strangles.

An overview of koala retrovirus epidemiology in Australia (2023)
Journal Article
Tarlinton, R. E. (2023). An overview of koala retrovirus epidemiology in Australia. Technical Reports of the Australian Museum (online), 38, 3-6. https://doi.org/10.3853/j.1835-4211.38.2023.1831

Koala retrovirus (KoRV) epidemiology varies across koala (Phascolarctos cinereus) populations with distinct differences in viral prevalence, sequence diversity, and disease impact. Curiously the more genetically restricted southern populations are le... Read More about An overview of koala retrovirus epidemiology in Australia.

Synthesis of discussions of the Second Koala Retrovirus Workshop, 2021 (2023)
Journal Article
Greenwood, A. D., Alquezar-Planas, D. E., McKay, P. A., Mulot, B., Pye, G. W., Robbins, A., …Higgins, D. P. (2023). Synthesis of discussions of the Second Koala Retrovirus Workshop, 2021. Technical Reports of the Australian Museum (online), 38, 53-82. https://doi.org/10.3853/j.1835-4211.38.2023.1842

This document represents a synthesis of discussions held online at the Second Koala Retrovirus Workshop in 2021. The three days of discussions were based on workshop presentations and comprise: KoRV foundational science (Day 1); applied management of... Read More about Synthesis of discussions of the Second Koala Retrovirus Workshop, 2021.

Morphology of migrating telocytes and their potential role in stem cell differentiation during cartilage development in catfish (Clarias gariepinus) (2023)
Journal Article
Abd-Elhafeez, H. H., Rutland, C. S., & Soliman, S. A. (2023). Morphology of migrating telocytes and their potential role in stem cell differentiation during cartilage development in catfish (Clarias gariepinus). Microscopy Research and Technique, 86(9), 1108-1121. https://doi.org/10.1002/jemt.24374

Telocytes (TCs) are present in a broad range of species and regulate processes including homeostasis, tissue regeneration and immunosurveillance. This novel study describes the morphological features of migrating TCs and their role during cartilage d... Read More about Morphology of migrating telocytes and their potential role in stem cell differentiation during cartilage development in catfish (Clarias gariepinus).

Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology (2023)
Journal Article
Apaa, T., Withers, A. J., Staley, C. E., Blanchard, A. M., Bennett, M., Bremner-Harrison, S., …Tarlinton, R. E. (2023). Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology. Journal of General Virology, 104(6), Article 001859. https://doi.org/10.1101/2023.02.14.528476

Horseshoe bats are the natural hosts of the Sarbecovirus subgenus that includes SARS-CoV and SARS-CoV- 2. Despite the devastating impact of the COVID-19 pandemic, there is still little known about the underlying epidemiology and virology of sarbecovi... Read More about Sarbecoviruses of British Horseshoe Bats; Sequence Variation and Epidemiology.

“I didn’t see a sheep”: perspectives of lecturers and students at veterinary schools in Great Britain on learning about lameness in sheep (2023)
Journal Article
Clifton, R., Bamford, K., & Green, L. (2023). “I didn’t see a sheep”: perspectives of lecturers and students at veterinary schools in Great Britain on learning about lameness in sheep. Frontiers in Veterinary Science, 10, Article 1171853. https://doi.org/10.3389/fvets.2023.1171853

Introduction: Great Britain has over 15 million ewes. Lameness is one of the top three most economically important diseases for the sheep industry, costing about £80 million per annum. The prevalence of lameness reduced from 10% to 5% between 2004 an... Read More about “I didn’t see a sheep”: perspectives of lecturers and students at veterinary schools in Great Britain on learning about lameness in sheep.

Novel holistic pharmacokinetic model applied to plasma and urine concentrations of 2,5‐dihydroxybenzene sulphonate following administrations of calcium dobesilate and etamsylate to exercised horses (2023)
Journal Article
Paine, S. W., Harding, C., Waller, C. C., Zemenova, J., Viljanto, M., Habershon Butcher, J., & Hincks, P. R. (2023). Novel holistic pharmacokinetic model applied to plasma and urine concentrations of 2,5‐dihydroxybenzene sulphonate following administrations of calcium dobesilate and etamsylate to exercised horses. Journal of Veterinary Pharmacology and Therapeutics, 46(6), 365-374. https://doi.org/10.1111/jvp.13387

AbstractCalcium dobesilate (CD) is a synthetic venoactive drug used in veterinary medicine to treat equine navicular disease. Etamsylate is a haemostatic agent used in horses for the treatment of exercise‐induced pulmonary haemorrhage. Both etamsylat... Read More about Novel holistic pharmacokinetic model applied to plasma and urine concentrations of 2,5‐dihydroxybenzene sulphonate following administrations of calcium dobesilate and etamsylate to exercised horses.

Repeat patient testing-quality control with canine samples shows promise as an alternative to commercial quality control material for a network of 4 Sysmex XT2000iV hematology analyzers (2023)
Journal Article
Daly, S., Graham, P., & Freeman, K. P. (2024). Repeat patient testing-quality control with canine samples shows promise as an alternative to commercial quality control material for a network of 4 Sysmex XT2000iV hematology analyzers. Veterinary Clinical Pathology, 53(S1), 39-47. https://doi.org/10.1111/vcp.13211

Background Repeat patient testing-quality control (RPT-QC) uses retained patient samples as an alternative to commercial quality control material (QCM). We elected to calculate and validate RPT-QC limits for red blood cell count (RBC), hemoglobin (H... Read More about Repeat patient testing-quality control with canine samples shows promise as an alternative to commercial quality control material for a network of 4 Sysmex XT2000iV hematology analyzers.

Encapsulated papillary carcinoma of the breast: does it have a native basement membrane? (2023)
Journal Article
Ghannam, S. F., Rutland, C. S., Allegrucci, C., Mongan, N. P., & Rakha, E. (2023). Encapsulated papillary carcinoma of the breast: does it have a native basement membrane?. Histopathology, 83(3), 376-393. https://doi.org/10.1111/his.14939

Background Encapsulated papillary carcinoma (EPC) is surrounded by a thick fibrous capsule-like structure, which is interpreted as a thickened basement membrane (BM). This study aimed to describe the geometric characteristics of the EPC capsule and... Read More about Encapsulated papillary carcinoma of the breast: does it have a native basement membrane?.

Global prevalence and factors affecting the level of Cryptosporidium contamination in soil: A systematic review, meta-analysis, and meta-regression (2023)
Journal Article
Zuo, M., Li, X., Xu, R., Sun, W., Elsheikha, H. M., & Cong, W. (2023). Global prevalence and factors affecting the level of Cryptosporidium contamination in soil: A systematic review, meta-analysis, and meta-regression. Science of the Total Environment, 891, Article 164286. https://doi.org/10.1016/j.scitotenv.2023.164286

Soil contamination with Cryptosporidium is a serious environmental and public health concern. In this systematic review and meta-analysis we estimated the global prevalence of Cryptosporidium contamination in soil and evaluated its association with c... Read More about Global prevalence and factors affecting the level of Cryptosporidium contamination in soil: A systematic review, meta-analysis, and meta-regression.

Predicting bioactivity of antibiotic metabolites by molecular docking and dynamics (2023)
Journal Article
Chio, H., Guest, E. E., Hobman, J. L., Dottorini, T., Hirst, J. D., & Stekel, D. J. (2023). Predicting bioactivity of antibiotic metabolites by molecular docking and dynamics. Journal of Molecular Graphics and Modelling, 123, Article 108508. https://doi.org/10.1016/j.jmgm.2023.108508

Antibiotics enter the environment through waste streams, where they can exert selective pressure for antimicrobial resistance in bacteria. However, many antibiotics are excreted as partly metabolized forms, or can be subject to partial breakdown in w... Read More about Predicting bioactivity of antibiotic metabolites by molecular docking and dynamics.

Characteristics and prognostic significance of polo-like kinase-1 (PLK1) expression in breast cancer (2023)
Journal Article
Lashen, A. G., Toss, M. S., Wootton, L., Green, A. R., Mongan, N. P., Madhusudan, S., & Rakha, E. (2023). Characteristics and prognostic significance of polo-like kinase-1 (PLK1) expression in breast cancer. Histopathology, 83(3), 414-425. https://doi.org/10.1111/his.14960

Background: Polo-like kinase-1 (PLK1) plays a crucial role in cell cycle progression,and it is considered a potential therapeutic target in many cancers. Although the role of PLK1 is well established in triple negative breast cancer (TNBC) as an onco... Read More about Characteristics and prognostic significance of polo-like kinase-1 (PLK1) expression in breast cancer.