Skip to main content

Research Repository

Advanced Search

All Outputs (104)

Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells (2015)
Journal Article
Al-Mubarak, F., Daly, J., Christie, D., Fountain, D., & Dunham, S. P. (2015). Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells. Virus Research, 199, 9-19. https://doi.org/10.1016/j.virusres.2015.01.005

Although wild ducks are considered to be the major reservoirs for most influenza A virus subtypes, they are typically resistant to the effects of the infection. In contrast, certain influenza viruses may be highly pathogenic in other avian hosts such... Read More about Identification of morphological differences between avian influenza A viruses grown in chicken and duck cells.

Low body condition predisposes cattle to lameness: An 8-year study of one dairy herd (2015)
Journal Article
Rndall, L., Green, M., Chagunda, M., Mason, C., Archer, S., Green, L., & Huxley, J. (2015). Low body condition predisposes cattle to lameness: An 8-year study of one dairy herd. Journal of Dairy Science, 98(6), https://doi.org/10.3168/jds.2014-8863

Lameness in dairy cows is a multifactorial and progressive disease with complex interactions between risk factors contributing to its occurrence. Detailed records were obtained from one United Kingdom dairy herd over an 8-yr period. Weekly locomotion... Read More about Low body condition predisposes cattle to lameness: An 8-year study of one dairy herd.

A predictive model for canine dilated cardiomyopathy: a meta-analysis of Doberman Pinscher data (2015)
Journal Article
Simpson, S., Edwards, J., Emes, R. D., Cobb, M. A., Mongan, N. P., & Rutland, C. S. (2015). A predictive model for canine dilated cardiomyopathy: a meta-analysis of Doberman Pinscher data. PeerJ, 3, Article e842. https://doi.org/10.7717/peerj.842

Dilated cardiomyopathy is a prevalent and often fatal disease in humans and dogs. Indeed dilated cardiomyopathy is the third most common form of cardiac disease in humans, reported to affect approximately 36 individuals per 100,000 individuals. In do... Read More about A predictive model for canine dilated cardiomyopathy: a meta-analysis of Doberman Pinscher data.

DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells (2015)
Journal Article
Kuchipudi, S., Chang, K., & Dunham, S. (2015). DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells. Genomics Data, 4, 60-64. https://doi.org/10.1016/j.gdata.2015.03.004

The data described in this article pertain to the article by Kuchipudi et al. (2014) titled “Highly Pathogenic Avian Influenza Virus Infection in Chickens But Not Ducks Is Associated with Elevated Host Immune and Pro-inflammatory Responses” [1]. Whil... Read More about DNA microarray global gene expression analysis of influenza virus-infected chicken and duck cells.

Exploiting heterogeneous environments: does photosynthetic acclimation optimize carbon gain in fluctuating light? (2015)
Journal Article
Retkute, R., Smith-Unna, S. E., Smith, R. W., Burgess, A. J., Jensen, O. E., Johnson, G. N., …Murchie, E. H. (2015). Exploiting heterogeneous environments: does photosynthetic acclimation optimize carbon gain in fluctuating light?. Journal of Experimental Botany, 66(9), 2437-2447. https://doi.org/10.1093/jxb/erv055

Plants have evolved complex mechanisms to balance the efficient use of absorbed light energy in photosynthesis with the capacity to use that energy in assimilation, so avoiding potential damage from excess light. This is particularly important under... Read More about Exploiting heterogeneous environments: does photosynthetic acclimation optimize carbon gain in fluctuating light?.

Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows (2015)
Journal Article
Daly, J. M., King, B., Tarlinton, R. A., Gough, K. C., Maddison, B. C., & Blowey, R. (2015). Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows. BMC Veterinary Research, 11, Article 56. https://doi.org/10.1186/s12917-015-0365-1

© Daly et al.; licensee BioMed Central. Background: Schmallenberg virus (SBV) is a recently emerged virus of ruminants in Europe. Enzyme-linked immunosorbent assays (ELISA) are commonly used to detect SBV-specific antibodies in bulk tank milk samples... Read More about Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development (2015)
Journal Article
Japa, O., Hodgkinson, J. E., Emes, R. D., & Flynn, R. J. (2015). TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development. Veterinary Research, 46(1), Article 29. https://doi.org/10.1186/s13567-015-0167-2

© 2015 Japa et al.; licensee BioMed Central. The helminth Fasciola hepatica causes fasciolosis throughout the world, a major disease of livestock and an emerging zoonotic disease in humans. Sustainable control mechanisms such as vaccination are urgen... Read More about TGF-? superfamily members from the helminth Fasciola hepatica show intrinsic effects on viability and development.

Regional differences of testicular artery blood flow in post pubertal and pre-pubertal dogs (2015)
Journal Article
de Souza, M. B., Barbosa, C. C., England, G. C., Mota Filho, A. C., Sousa, C. V. S., de Carvalho, G. G., …Silva, L. D. (2015). Regional differences of testicular artery blood flow in post pubertal and pre-pubertal dogs. BMC Veterinary Research, 11(1), Article 47. https://doi.org/10.1186/s12917-015-0363-3

Background Measurement of testicular artery blood flow is used in several species to evaluate reproductive function and testicular and scrotal pathology. In dogs there are inconsistent reports about normal flow in post-pubertal dogs and no informa... Read More about Regional differences of testicular artery blood flow in post pubertal and pre-pubertal dogs.

Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system (2015)
Journal Article
Kurlak, L., Williams, P. J., Bulmer, J. N., Broughton Pipkin, F., & Mistry, H. D. (2015). Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system. Placenta, 36(5), https://doi.org/10.1016/j.placenta.2015.02.011

Normal placentation occurs under low oxygen tensions yet hypoxia is also implicated in placental pathologies such as pre-eclampsia (PE). Hypoxia-inducible factors (HIFs), adenosine and tissue renin-angiotensin-system (RAS) are known to promote angiog... Read More about Placental expression of adenosine A2A receptor and hypoxia inducible factor-1 alpha in early pregnancy, term and pre-eclamptic pregnancies: interactions with placental renin-angiotensin system.

Animals and anomalies: an analysis of the UK veterinary profession and the relative lack of state reform (2015)
Journal Article
Hobson-West, P., & Timmons, S. (2016). Animals and anomalies: an analysis of the UK veterinary profession and the relative lack of state reform. Sociological Review, 64(1), 47-63. https://doi.org/10.1111/1467-954X.12254

The sociology of professions literature would predict that the contemporary state would not allow groups to continue unregulated or unreformed. However, this is indeed the case with the UK veterinary profession, with legislation dating back to 1966.... Read More about Animals and anomalies: an analysis of the UK veterinary profession and the relative lack of state reform.

Arginine dependence of acute myeloid leukaemia blast proliferation: a novel therapeutic target (2015)
Journal Article
Mussai, F., Egan, S. A., Higginbotham-Jones, J., Perry, T., Beggs, A., Odintsova, E., …De Santo, C. (2015). Arginine dependence of acute myeloid leukaemia blast proliferation: a novel therapeutic target. Blood, 125(15), https://doi.org/10.1182/blood-2014-09-600643

Acute myeloid leukemia (AML) is one of the most common acute leukemias in adults and children, yet significant numbers of patients relapse and die of disease. In this study, we identify the dependence of AML blasts on arginine for proliferation. We s... Read More about Arginine dependence of acute myeloid leukaemia blast proliferation: a novel therapeutic target.

IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c (2015)
Journal Article
Higgins, J., Mutamba, S., Mahida, Y. R., Barrow, P., & Foster, N. (2015). IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c. Human Immunology, 76(4), https://doi.org/10.1016/j.humimm.2015.01.012

We show that IL-36? induced maturation of human MDDCs and stimulated differentiation of IFN-? producing (Type 1) CD3+ lymphocytes but was not as effective as IL-36? in doing so. For the first time, we also show that IL-36? induced expression of CD14... Read More about IL-36? induces maturation of Th1-inducing human MDDC and synergises with IFN-? to induce high surface expression of CD14 and CD11c.

The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses (2015)
Journal Article
Gao, H., Sun, Y., Hu, J., Qi, L., Wang, J., Xiong, X., …Liu, J. (in press). The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses. Scientific Reports, 5(1), https://doi.org/10.1038/srep08262

PA-X is a novel protein encoded by PA mRNA and is found to decrease the pathogenicity of pandemic 1918 H1N1 virus in mice. However, the importance of PA-X proteins in current epidemiologically important influenza A virus strains is not known. In this... Read More about The contribution of PA-X to the virulence of pandemic 2009 H1N1 and highly pathogenic H5N1 avian influenza viruses.

Triaging informative cis-regulatory elements for the combinatorial control of temporal gene expression during Plasmodium falciparum intraerythrocytic development (2015)
Journal Article
Russell, K., Emes, R. D., & Horrocks, P. (2015). Triaging informative cis-regulatory elements for the combinatorial control of temporal gene expression during Plasmodium falciparum intraerythrocytic development. Parasites and Vectors, 8(81), https://doi.org/10.1186/s13071-015-0701-0

Background: Over 2700 genes are subject to stage-specific regulation during the intraerythrocytic development of the human malaria parasite Plasmodium falciparum. Bioinformatic analyses have identified a large number of over-represented motifs in the... Read More about Triaging informative cis-regulatory elements for the combinatorial control of temporal gene expression during Plasmodium falciparum intraerythrocytic development.

Body composition and behaviour in adult rats are influenced by maternal diet, maternal age and high-fat feeding (2015)
Journal Article
Ware, S., Voigt, J., & Langley-Evans, S. C. (2015). Body composition and behaviour in adult rats are influenced by maternal diet, maternal age and high-fat feeding. Journal of Nutritional Science, 4(e3), https://doi.org/10.1017/jns.2014.64

Fetal exposure to maternal undernutrition has lifelong consequences for physiological and metabolic function. Maternal low-protein diet is associated with an age-related phenotype in rats, characterised by a period of resistance to development of obe... Read More about Body composition and behaviour in adult rats are influenced by maternal diet, maternal age and high-fat feeding.

Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring (2015)
Journal Article
Dellschaft, N. S., Alexandre-Gouabau, M., Gardner, D. S., Antignac, J., Keisler, D. H., Budge, H., …Sebert, S. P. (2015). Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring. Journal of Endocrinology, 224(2), https://doi.org/10.1530/JOE-14-0600

Maternal caloric restriction during late gestation reduces birth weight, but whether long-term adverse metabolic outcomes of intra-uterine growth retardation (IUGR) are dependent on either accelerated postnatal growth or exposure to an obesogenic env... Read More about Effect of pre- and postnatal growth and post-weaning activity on glucose metabolism in the offspring.

Area of hock hair loss in dairy cows : risk factors and correlation to a categorical scale (2015)
Journal Article
Lim, P., Huxley, J., Green, M. J., Othman, A., Potterton, S., Brignell, C., & Kaler, J. (2015). Area of hock hair loss in dairy cows : risk factors and correlation to a categorical scale. Veterinary Journal, 203(2), https://doi.org/10.1016/j.tvjl.2014.11.005

Data from 3691 dairy cows from 76 farms were used to investigate the risk factors associated with area of hair loss over the lateral aspect of the hock, and the correlation between the area of hair loss as calculated using a hock map and hock lesion... Read More about Area of hock hair loss in dairy cows : risk factors and correlation to a categorical scale.

Skin malformations in a neonatal foal tested homozygous positive for Warmblood Fragile Foal Syndrome (2015)
Journal Article
Monthoux, C., de Brot, S., Jackson, M., Bleul, U., & Walter, J. (2015). Skin malformations in a neonatal foal tested homozygous positive for Warmblood Fragile Foal Syndrome. BMC Veterinary Research, 11(12), https://doi.org/10.1186/s12917-015-0318-8

BACKGROUND: Skin malformations that resembled manifestations of Ehlers-Danlos-Syndrome were described in a variety of domestic animals during the last century as cutis hyperelastica, hyperelastosis cutis, dermatosparaxis, dermal/collagen dysplasia... Read More about Skin malformations in a neonatal foal tested homozygous positive for Warmblood Fragile Foal Syndrome.

Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis (2015)
Journal Article
Hudson, C. D., Bradley, A. J., Breen, J. E., & Green, M. J. (2015). Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis. Veterinary Journal, 204(1), https://doi.org/10.1016/j.tvjl.2015.01.024

Probabilistic sensitivity analysis (PSA) is a simulation-based technique for evaluating the relative importance of different inputs to a complex process model. It is commonly employed in decision analysis and for evaluation of the potential impact of... Read More about Dairy herd mastitis and reproduction: using simulation to aid interpretation of results from discrete time survival analysis.