Neuroimaging paradigms for tonotopic mapping (II): the influence of acquisition protocol.
(2014)
Journal Article
All Outputs (111)
Functional quantitative susceptibility mapping (fQSM) (2014)
Journal Article
Blood oxygenation level dependent (BOLD) functional magnetic resonance imaging (fMRI) is a powerful technique, typically based on the statistical analysis of the magnitude component of the complex time-series. Here, we additionally interrogated the p... Read More about Functional quantitative susceptibility mapping (fQSM).
Objective: We compared the effects of intravenous administration of 6% hydroxyethyl starch (maize-derived) in 0.9% saline (Voluven; Fresenius Kabi, Runcorn, United Kingdom) and a “balanced” preparation of 6% hydroxyethyl starch (potato-derived) [Plas... Read More about A Randomized, Controlled, Double-Blind Crossover Study on the Effects of 1-L Infusions of 6% Hydroxyethyl Starch Suspended in 0.9% Saline (Voluven) and a Balanced Solution (Plasma Volume Redibag) on Blood Volume, Renal Blood Flow Velocity, and Renal Cortical Tissue Perfusion in Healthy Volunteers.
Evidence that the negative BOLD response is neuronal in origin: a simultaneous EEG–BOLD–CBF study in humans (2014)
Journal Article
Unambiguous interpretation of changes in the BOLD signal is challenging because of the complex neurovascular coupling that translates changes in neuronal activity into the subsequent haemodynamic response. In particular, the neurophysiological origin... Read More about Evidence that the negative BOLD response is neuronal in origin: a simultaneous EEG–BOLD–CBF study in humans.
Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects (2013)
Journal Article
Recent fMRI studies of the human primary somatosensory cortex have been able to differentiate the cortical representations of different fingertips at a single-subject level. These studies did not, however, investigate the expected overlap in cortical... Read More about Event-related fMRI at 7T reveals overlapping cortical representations for adjacent fingertips in S1 of individual subjects.
Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans (2013)
Journal Article
Twelve weeks of daily L-carnitine and carbohydrate feeding in humans increases skeletal muscle total carnitine content, and prevents body mass accrual associated with carbohydrate feeding alone. Here we determined the influence of L-carnitine and car... Read More about Skeletal muscle carnitine loading increases energy expenditure, modulates fuel metabolism gene networks and prevents body fat accumulation in humans.
Poststimulus undershoots in cerebral blood flow and BOLD fMRI responses are modulated by poststimulus neuronal activity (2013)
Journal Article
fMRI is the foremost technique for noninvasive measurement of human brain function. However, its utility is limited by an incomplete understanding of the relationship between neuronal activity and the hemodynamic response. Though the primary peak of... Read More about Poststimulus undershoots in cerebral blood flow and BOLD fMRI responses are modulated by poststimulus neuronal activity.
Regional structural differences across functionally parcellated Brodmann areas of human primary somatosensory cortex (2013)
Journal Article
Ultra-high-field (UHF) MRI is ideally suited for structural and functional imaging of the brain. High-resolution structural MRI can be used to map the anatomical boundaries between functional domains of the brain by identifying changes related to the... Read More about Regional structural differences across functionally parcellated Brodmann areas of human primary somatosensory cortex.
Calibrated BOLD using direct measurement of changes in venous oxygenation (2012)
Journal Article
Calibration of the BOLD signal is potentially of great value in providing a closer measure of the underlying changes in brain function related to neuronal activity than the BOLD signal alone, but current approaches rely on an assumed relationship bet... Read More about Calibrated BOLD using direct measurement of changes in venous oxygenation.
Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data (2012)
Journal Article
The simultaneous acquisition and subsequent analysis of EEG and fMRI data is challenging owing to increased noise levels in the EEG data. A common method to integrate data from these two modalities is to use aspects of the EEG data, such as the ampli... Read More about Motion-related artefacts in EEG predict neuronally plausible patterns of activation in fMRI data.
The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia (2010)
Journal Article
Mapping cerebrovascular reactivity (CVR) to hypercapnia is important both clinically and for improved understanding of the haemodynamic properties of the BOLD effect. In this work BOLD/R2* CVR was investigated by using a device which provided small,... Read More about The change in cerebrovascular reactivity between 3T and 7T measured using graded hypercapnia.