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Fabrication and assessment of a bio-inspired synthetic tracheal tissue model for tracheal tube cuff leakage testing (2024)
Journal Article
Agbiki, T., Arm, R., Hewson, D. W., Erdody, S., Norris, A. M., Correia, R., …Morgan, S. P. (2024). Fabrication and assessment of a bio-inspired synthetic tracheal tissue model for tracheal tube cuff leakage testing. BJA Open, 10, Article 100290. https://doi.org/10.1016/j.bjao.2024.100290

Introduction Leakage of orogastric secretions past the cuff of a tracheal tube is a contributory factor in ventilator-associated pneumonia. Current bench test methods specified in the International Standard for Anaesthetic and Respiratory Equipment... Read More about Fabrication and assessment of a bio-inspired synthetic tracheal tissue model for tracheal tube cuff leakage testing.

Pulse oximeter bench tests under different simulated skin tones (2024)
Journal Article
Swamy, S. K. N., He, C., Hayes‑Gill, B. R., Hayes-Gill, B. R., Clark, D. J., Green, S., & Morgan, S. P. (2024). Pulse oximeter bench tests under different simulated skin tones. Medical and Biological Engineering and Computing, https://doi.org/10.1007/s11517-024-03091-2

Pulse oximeters’ (POs) varying performance based on skin tones has been highly publicised. Compared to arterial blood gas analysis, POs tend to overestimate oxygen saturation (SpO2) values for people with darker skin (occult hypoxemia). The objective... Read More about Pulse oximeter bench tests under different simulated skin tones.

Highly sensitive optical fibre Bragg grating contact pressure sensor embedded in a polymer layer: modelling and experimental validation (2024)
Journal Article
Abeywardena, C., Zhang, Q., Korposh, S., Morgan, S., Bull, S., & Correia, R. (2024). Highly sensitive optical fibre Bragg grating contact pressure sensor embedded in a polymer layer: modelling and experimental validation. Results in Optics, 14, Article 100604. https://doi.org/10.1016/j.rio.2024.100604

This paper discusses mathematical modelling and experimental validation of a highly sensitive optical fibre Bragg grating (FBG) contact pressure sensor developed for healthcare applications. Bare FBGs are not very sensitive to pressure (~ 3x10-3 nm/M... Read More about Highly sensitive optical fibre Bragg grating contact pressure sensor embedded in a polymer layer: modelling and experimental validation.

Forehead monitoring of heart rate in neonatal intensive care (2023)
Journal Article
Stockwell, S. J., Kwok, T. C., Morgan, S. P., Sharkey, D., & Hayes-Gill, B. R. (2023). Forehead monitoring of heart rate in neonatal intensive care. Frontiers in Physiology, 14, Article 1127419. https://doi.org/10.3389/fphys.2023.1127419

Heart rate is an extremely important physiological parameter to measure in critically unwell infants, as it is the main physiological marker that changes in response to a change in infant condition. Heart rate is routinely measured peripherally on a... Read More about Forehead monitoring of heart rate in neonatal intensive care.

A quantitative laser speckle-based velocity prediction approach using machine learning (2023)
Journal Article
Hao, X., Wu, S., Lin, L., Chen, Y., Morgan, S. P., & Sun, S. (2023). A quantitative laser speckle-based velocity prediction approach using machine learning. Optics and Lasers in Engineering, 166, Article 107587. https://doi.org/10.1016/j.optlaseng.2023.107587

Laser speckle contrast imaging (LSCI) can be applied to non-invasive blood perfusion measurement with high resolution and fast speed. However, it is lack of measurement accuracy. The aim of this study is to enable quantitative measurement of LSCI by... Read More about A quantitative laser speckle-based velocity prediction approach using machine learning.

Long Period Grating Mach–Zehnder Interferometer Based Immunosensor with Temperature and Bulk Refractive Index Compensation (2022)
Journal Article
Wu, P., Liu, L., Morgan, S. P., Correia, R., & Korposh, S. (2022). Long Period Grating Mach–Zehnder Interferometer Based Immunosensor with Temperature and Bulk Refractive Index Compensation. Biosensors, 12(12), Article 1099. https://doi.org/10.3390/bios12121099

A long period grating Mach–Zehnder interferometer (LPGMZI) that consists of two identical long period gratings (LPGs) in a single fibre was developed to measure immunoglobulin M (IgM). The measured spectrum has fringes due to the interference between... Read More about Long Period Grating Mach–Zehnder Interferometer Based Immunosensor with Temperature and Bulk Refractive Index Compensation.

U-shape functionalized optical fibre sensors for measurement of anaesthetic propofol (2022)
Journal Article
Hernandez, F. U., Wang, T., Lee, S. W., Norris, A., Liu, L. L., Hayes-Gill, B. R., …Korposh, S. (2022). U-shape functionalized optical fibre sensors for measurement of anaesthetic propofol. Sensors and Actuators B: Chemical, 372, Article 132653. https://doi.org/10.1016/j.snb.2022.132653

Propofol is used widely for intravenous anaesthesia during surgery and sedation in critical care. There is no method currently to assay the concentration of propofol in plasma in real time. The ability to do so would significantly improve patient saf... Read More about U-shape functionalized optical fibre sensors for measurement of anaesthetic propofol.

Fibre Bragg Grating Based Interface Pressure Sensor for Compression Therapy (2022)
Journal Article
Bradbury, J. A., Zhang, Q., Hernandez Ledezma, F. U., Correia, R., Korposh, S., Hayes-Gill, B. R., …Morgan, S. P. (2022). Fibre Bragg Grating Based Interface Pressure Sensor for Compression Therapy. Sensors, 22(5), Article 1798. https://doi.org/10.3390/s22051798

Compression therapy is widely used as the gold standard for management of chronic venous insufficiency and venous leg ulcers, and the amount of pressure applied during the compression therapy is crucial in supporting healing. A fibre optic pressure s... Read More about Fibre Bragg Grating Based Interface Pressure Sensor for Compression Therapy.

Feasibility of a Novel ECG Electrode Placement Method in Newborn Infants (2022)
Journal Article
Henry, C., Shipley, L., Morgan, S., Crowe, J. A., Carpenter, J., Hayes-Gill, B., & Sharkey, D. (2022). Feasibility of a Novel ECG Electrode Placement Method in Newborn Infants. Neonatology, 119(2), 264-267. https://doi.org/10.1159/000521530

Background: International newborn resuscitation guidelines recommend electrocardiogram (ECG) heart rate (HR) monitoring at birth. We evaluated the application time of pre-set ECG electrodes fixed to a polyethene patch allowing adhesive-free attachmen... Read More about Feasibility of a Novel ECG Electrode Placement Method in Newborn Infants.

Intra-tracheal multiplexed sensing of contact pressure and perfusion (2021)
Journal Article
Correia, R., Gadsby, B., Korposh, S., Norris, A. M., Hayes-Gill, B. R., Sinha, R., …Morgan, S. P. (2022). Intra-tracheal multiplexed sensing of contact pressure and perfusion. Biomedical Optics Express, 13(1), 48-64. https://doi.org/10.1364/BOE.442165

Incorrect endotracheal tube (ETT) cuff inflation pressure causes significant problems for intubated patients. The technical development and first in vivo use of a smart ETT for measurements at the cuff-trachea interface during mechanical ventilation... Read More about Intra-tracheal multiplexed sensing of contact pressure and perfusion.

Optical Fibre Sensor for Capillary Refill Time and Contact Pressure Measurements under the Foot (2021)
Journal Article
Ballaji, H. K., Correia, R., Liu, C., Korposh, S., Hayes-Gill, B. R., Musgrove, A., & Morgan, S. P. (2021). Optical Fibre Sensor for Capillary Refill Time and Contact Pressure Measurements under the Foot. Sensors, 21(18), Article 6072. https://doi.org/10.3390/s21186072

Capillary refill time (CRT) refers to the time taken for body tissue to regain its colour after an applied blanching pressure is released. Usually, pressure is manually applied and not measured. Upon release of pressure, simple mental counting is typ... Read More about Optical Fibre Sensor for Capillary Refill Time and Contact Pressure Measurements under the Foot.

Non-invasive cuff-less blood pressure estimation using a hybrid deep learning model (2021)
Journal Article
Yang, S., Zhang, Y., Cho, S.-Y., Correia, R., & Morgan, S. P. (2021). Non-invasive cuff-less blood pressure estimation using a hybrid deep learning model. Optical and Quantum Electronics, 53(2), Article 93. https://doi.org/10.1007/s11082-020-02667-0

Conventional blood pressure (BP) measurement methods have different drawbacks such as being invasive, cuff-based or requiring manual operations. There is significant interest in the development of non-invasive, cuff-less and continual BP measurement... Read More about Non-invasive cuff-less blood pressure estimation using a hybrid deep learning model.

Development and validation of a novel fibre-optic respiratory rate sensor (FiRRS) integrated in oxygen delivery devices (2021)
Journal Article
Sinha, R., Hernandez, F., He, C., Korposh, S., Correia, R. N. G., Norris, A., …Morgan, S. P. (2021). Development and validation of a novel fibre-optic respiratory rate sensor (FiRRS) integrated in oxygen delivery devices. Journal of Physics D: Applied Physics, 54(12), Article 124002. https://doi.org/10.1088/1361-6463/abd061

© 2021 The Author(s). Respiratory rate (RR) monitoring provides crucial information on the overall health condition of patients and a reliable, low cost RR monitor for normal hospital inpatient or home use would be of significant benefit. The propose... Read More about Development and validation of a novel fibre-optic respiratory rate sensor (FiRRS) integrated in oxygen delivery devices.

A Textile Sleeve for Monitoring Oxygen Saturation Using Multichannel Optical Fibre Photoplethysmography (2020)
Journal Article
Ballaji, H. K., Correia, R., Korposh, S., Hayes-Gill, B. R., Hernandez, F. U., Salisbury, B., & Morgan, S. P. (2020). A Textile Sleeve for Monitoring Oxygen Saturation Using Multichannel Optical Fibre Photoplethysmography. Sensors, 20(22), Article 6568. https://doi.org/10.3390/s20226568

Textile-based systems are an attractive prospect for wearable technology as they can provide monitoring of key physiological parameters in a comfortable and unobtrusive form. A novel system based on multichannel optical fibre sensor probes integrated... Read More about A Textile Sleeve for Monitoring Oxygen Saturation Using Multichannel Optical Fibre Photoplethysmography.

Accurate neonatal heart rate monitoring using a new wireless, cap mounted device (2020)
Journal Article
Henry, C., Shipley, L., Ward, C., Mirahmadi, S., Liu, C., Morgan, S., …Sharkey, D. (2020). Accurate neonatal heart rate monitoring using a new wireless, cap mounted device. Acta Paediatrica, 110(1), 72-78. https://doi.org/10.1111/apa.15303

© 2020 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica Aim: A device for newborn heart rate (HR) monitoring at birth that is compatible with delayed cord clamping and minimises hypothermia r... Read More about Accurate neonatal heart rate monitoring using a new wireless, cap mounted device.

Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure (2020)
Journal Article
Liu, C., Correia, R., Ballaji, H., Korposh, S., Hayes‐gill, B., & Morgan, S. (2020). Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure. Sensors, 20(5), Article 1388. https://doi.org/10.3390/s20051388

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. The widely applied capillary refill time (CRT) measurement is currently performed by manually applying pressure and using a stopwatch to record the time taken for the skin to recover its norma... Read More about Optical fibre sensor for simultaneous measurement of capillary refill time and contact pressure.

Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging (2019)
Journal Article
Zhang, Q., Grabowska, A. M., Clarke, P. A., & Morgan, S. P. (2019). Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging. Journal of Imaging, 5(11), Article 83. https://doi.org/10.3390/jimaging5110083

he spatial resolution and light detected in fluorescence imaging for small animals are limited by light scattering, absorption and autofluorescence. To address this, novel near-infrared fluorescent contrast agents and imaging configurations have been... Read More about Numerical Simulation of a Scanning Illumination System for Deep Tissue Fluorescence Imaging.

Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers (2018)
Journal Article
Yang, Q., Sun, S., Jeffcoate, W., Clark, D., Musgove, A., Game, F., & Morgan, S. (2018). Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers. Journal of Imaging, 4(12), Article 144. https://doi.org/10.3390/jimaging4120144

Diabetic foot ulcers are a major complication of diabetes and present a considerable burden for both patients and health care providers. As healing often takes many months, a method of determining which ulcers would be most likely to heal would be of... Read More about Investigation of the performance of hyperspectral imaging by principal component analysis in the prediction of healing of diabetic foot ulcers.

Biomedical application of optical fibre sensors (2018)
Journal Article
Correia, R., James, S., Lee, S.-W., Morgan, S., & Korposh, S. (2018). Biomedical application of optical fibre sensors. Journal of Optics, 20(7), Article 073003. https://doi.org/10.1088/2040-8986/aac68d

Optical fibre sensors(OFS), as a result of their unique properties such as small size, no interference with electromagnetic radiation, high sensitivity and the ability to design multiplexed or distributed sensing systems, have found applications rang... Read More about Biomedical application of optical fibre sensors.