All Outputs (71)

Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus? (2019)
Journal Article
Morandi, E., Tanasescu, R., Tarlington, R., Constantin-Teodosiu, D., & Gran, B. (2019). Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?. Frontiers in Immunology, 9, Article 3092. https://doi.org/10.3389/fimmu.2018.03092

The expression of human endogenous retroviruses (HERVs) has been associated with Multiple Sclerosis (MS). The MS-related retrovirus (MSRV/HERV-W) has the potential to activate inflammatory immunity, which could promote both susceptibility and progres... Read More about Do Antiretroviral Drugs Protect From Multiple Sclerosis By Inhibiting Expression Of MS-Associated Retrovirus?.

The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis (2019)
Journal Article
Tarlinton, R., Khaibullin, T., Granatov, E., Martynova, E., Rizvanov, A., & Khaiboullina, S. (2019). The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis. International Journal of Molecular Sciences, 20(2), 1-16. https://doi.org/10.3390/ijms20020303

Multiple sclerosis (MS) is a chronic debilitating inflammatory disease of unknown ethology targeting the central nervous system (CNS). MS has a polysymptomatic onset and is usually first diagnosed between the ages of 20–40 years. The pathology of the... Read More about The interaction between viral and environmental risk factors in the pathogenesis of multiple sclerosis.

Survey to determine the farm-level impact of Schmallenberg virus during the 2016–2017 United Kingdom lambing season (2018)
Journal Article
Stokes, J. E., Tarlinton, R. E., Lovatt, F., Baylis, M., Carson, A., & Duncan, J. S. (2018). Survey to determine the farm-level impact of Schmallenberg virus during the 2016–2017 United Kingdom lambing season. Veterinary Record, 183(22), 690-690. https://doi.org/10.1136/vr.104866

Schmallenberg virus (SBV) causes abortions, stillbirths and fetal malformations in naïve ruminants. The impact of the initial outbreak (2011/2012) on British sheep farms has been previously investigated, with higher farmer perceived impacts and incre... Read More about Survey to determine the farm-level impact of Schmallenberg virus during the 2016–2017 United Kingdom lambing season.

Identification of stable reference genes for quantitative PCR in koalas (2018)
Journal Article
Sarker, N., Fabijan, J., Emes, R. D., Hemmatzadeh, F., Meers, J., Moreton, J., Owen, H., Seddon, J., Simmons, G., Speight, N., Trott, D., Woolford, L., & Tarlinton, R. E. (2018). Identification of stable reference genes for quantitative PCR in koalas. Scientific Reports, 8(1), Article 3364. https://doi.org/10.1038/s41598-018-21723-0

To better understand host and immune response to diseases, gene expression studies require identification of reference genes with stable expression for accurate normalisation. This study describes the identification and testing of reference genes wit... Read More about Identification of stable reference genes for quantitative PCR in koalas.

Identification of stable reference genes for quantitative PCR in koalas (2018)
Journal Article
Sarker, N., Fabijan, J., Emes, R. D., Hemmatzadeh, F., Meers, J., Moreton, J., Owen, H., Seddon, J. M., Simmons, G., Speight, N., Trott, D., Woolford, L., & Tarlinton, R. (2018). Identification of stable reference genes for quantitative PCR in koalas. Scientific Reports, 8, Article 3364. https://doi.org/10.1101/215681

To better understand host and immune response to diseases, gene expression studies require identification of reference genes with stable expression for accurate normalisation. This study describes the identification and testing of reference genes wit... Read More about Identification of stable reference genes for quantitative PCR in koalas.

How is Europe positioned for a re-emergence of Schmallenberg virus? (2017)
Journal Article
Tarlinton, R., Gough, K., Maddison, B., Stavrou, A., Daly, J. M., Maddison, B. C., Gough, K. C., & Tarlinton, R. E. (2017). How is Europe positioned for a re-emergence of Schmallenberg virus?. Veterinary Journal, 230, 45-51. https://doi.org/10.1016/j.tvjl.2017.04.009

The Schmallenberg virus (SBV) caused a large scale epidemic in Europe from 2011–2013 infecting ruminants and causing fetal deformities after infection of pregnant animals. The main impacts of the virus were financial losses due to animal, meat and se... Read More about How is Europe positioned for a re-emergence of Schmallenberg virus?.

Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect? (2017)
Journal Article
Morandi, E., Tarlinton, R. E., Tanasescu, R., & Gran, B. (2017). Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect?. Multiple Sclerosis Journal, 23(8), 1050-1055. https://doi.org/10.1177/1352458517704711

© The Author(s), 2016. From the early days of MS discovery, infections have been proposed as a possible cause of the disease. In the last three decades, an association between human endogenous retrovirus expression and MS has been further investigate... Read More about Human endogenous retroviruses and multiple sclerosis: Causation, association, or after-effect?.

The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis (2017)
Journal Article
Morandi, E., Tanasescu, R., Tarlinton, R. E., Constantinescu, C. S., Zhang, W., Tench, C. R., & Gran, B. (2017). The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis. PLoS ONE, 12(2), Article e0172415. https://doi.org/10.1371/journal.pone.0172415

Background:
The interaction between genetic and environmental factors is crucial to multiple sclerosis (MS) pathogenesis. Human Endogenous Retroviruses (HERVs) are endogenous viral elements of the human genome whose expression is associated with MS.... Read More about The association between human endogenous retroviruses and multiple sclerosis: a systematic review and meta-analysis.

Canine parvovirus (CPV-2) variants circulating in Nigerian dogs (2016)
Journal Article
Apaa, T., Daly, J. M., & Tarlinton, R. E. (2016). Canine parvovirus (CPV-2) variants circulating in Nigerian dogs. Veterinary Record Open, 3(1), Article e000198. https://doi.org/10.1136/vetreco-2016-000198

Canine parvovirus type 2 (CPV-2) is a highly contagious viral disease with three variants (CPV-2a, CPV-2b and CPV-2c) currently circulating in dogs worldwide. The main aim of this study was to determine the prevalent CPV-2 variant in faecal samples f... Read More about Canine parvovirus (CPV-2) variants circulating in Nigerian dogs.

Is gibbon ape leukaemia virus still a threat? (2016)
Journal Article
Brown, K., & Tarlinton, R. E. (2016). Is gibbon ape leukaemia virus still a threat?. Mammal Review, 47(1), 53-61. https://doi.org/10.1111/mam.12079

In the late 1960s and early 1970s, an outbreak of lymphoma and leukaemia in gibbons (Hylobatidae), attributed to the retrovirus gibbon ape leukaemia virus (GALV), was widely reported in the literature. The virus was identified in captive gibbon colon... Read More about Is gibbon ape leukaemia virus still a threat?.

RNA expression of TLR10 in normal equine tissues (2016)
Journal Article
Tarlinton, R. E., Alder, L., Moreton, J., Maboni, G., Emes, R. D., & Tötemeyer, S. (2016). RNA expression of TLR10 in normal equine tissues. BMC Research Notes, 9, Article 353. https://doi.org/10.1186/s13104-016-2161-9

Background: Toll like receptors are one of the major innate immune system pathogen recognition systems. There is little data on the expression of the TLR10 member of this family in the horse.

Results: This paper describes the genetic structure of... Read More about RNA expression of TLR10 in normal equine tissues.

Discovery of novel alphacoronaviruses in European rodents and shrews (2016)
Journal Article
Tsoleridis, T., Onianwa, O., Horncastle, E., Dayman, E., Zhu, M., Danjittrong, T., Wachtl, M., Behnke, J. M., Chapman, S., Strong, V., Dodds, P., Tarlinton, R. E., Ball, J. K., & McClure, P. (2016). Discovery of novel alphacoronaviruses in European rodents and shrews. Viruses, 8(3), Article 84. https://doi.org/10.3390/v8030084

Eight hundred and thirteen European rodents and shrews encompassing seven different species were screened for alphacoronaviruses using PCR detection. Novel alphacoronaviruses were detected in the species Rattus norvegicus, Microtus agrestis, Sorex ar... Read More about Discovery of novel alphacoronaviruses in European rodents and shrews.

Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages (2015)
Journal Article
Morandi, E., Tarlinton, R., & Gran, B. (2015). Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages. Frontiers in Immunology, 6, https://doi.org/10.3389/fimmu.2015.00647

The etiology of multiple sclerosis (MS) is still unknown, but there is strong evidence that genetic predisposition associated with environmental factors can trigger the disease. An estimated 30 million years ago, exogenous retroviruses are thought to... Read More about Multiple sclerosis between genetics and infections: human endogenous retroviruses in monocytes and macrophages.

Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy (2015)
Journal Article
Bennett, L., Dunham, S. P., Yon, L., Chapman, S., Kenaghan, M., Purdie, L., & Tarlinton, R. E. (2015). Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy. Veterinary Record Open, 2(1), Article e000088. https://doi.org/10.1136/vetreco-2014-000088

Introduction: EEHV-1 is a viral infection of elephants that has been associated with a fatal haemorrhagic syndrome in Asian elephants. Previous studies have suggested that pregnant animals may shed more virus than non-pregnant animals.
Methods: This... Read More about Longitudinal study of Asian elephants, Elephas maximus, indicates intermittent shedding of elephant endotheliotropic herpesvirus 1 during pregnancy.

Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013 (2015)
Journal Article
Tarlinton, R., King, B., O'Shea Brown, T., & Daly, J. M. (2015). Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013. Veterinary Microbiology, 180(1-2), 36-40. https://doi.org/10.1016/j.vetmic.2015.07.025

© 2015 Elsevier B.V. Since its identification in late 2011, Schmallenberg virus (SBV) spread rapidly across Europe. Using archived samples from domestic ruminants collected between October 2011 and June 2013, the seroprevalence in the United Kingdom... Read More about Seroprevalence of Schmallenberg virus in the United Kingdom and the Republic of Ireland: 2011-2013.

Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows (2015)
Journal Article
Daly, J. M., King, B., Tarlinton, R. A., Gough, K. C., Maddison, B. C., & Blowey, R. (2015). Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows. BMC Veterinary Research, 11, Article 56. https://doi.org/10.1186/s12917-015-0365-1

© Daly et al.; licensee BioMed Central. Background: Schmallenberg virus (SBV) is a recently emerged virus of ruminants in Europe. Enzyme-linked immunosorbent assays (ELISA) are commonly used to detect SBV-specific antibodies in bulk tank milk samples... Read More about Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

Multiple groups of endogenous epsilon-like retroviruses conserved across primates (2014)
Journal Article
Brown, K., Emes, R. D., & Tarlinton, R. E. (2014). Multiple groups of endogenous epsilon-like retroviruses conserved across primates. Journal of Virology, 88(21), https://doi.org/10.1128/JVI.00966-14

Several types of cancer in fish are caused by retroviruses, including those responsible for major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim bladder sarcoma virus. These viruses form a phylogenetic group often describe... Read More about Multiple groups of endogenous epsilon-like retroviruses conserved across primates.

Characterisation of the horse transcriptome from immunologically active tissues (2014)
Journal Article
Moreton, J., Malla, S., Aboobaker, A., Tarlinton, R. E., & Emes, R. D. (2014). Characterisation of the horse transcriptome from immunologically active tissues. PeerJ, 2, Article e382. https://doi.org/10.7717/peerj.382

The immune system of the horse has not been well studied, despite the fact that the horse displays several features such as sensitivity to bacterial lipopolysaccharide that make them in many ways a more suitable model of some human disorders than the... Read More about Characterisation of the horse transcriptome from immunologically active tissues.

Schmallenberg virus update (2014)
Journal Article
Tarlinton, R. (2014). Schmallenberg virus update. Cattle Practice, 22, 65

Since emerging in Europe in 2011 Schmallenberg Virus (SBV) has affected over 6000 holdings over most of the continent. The virus causes mild disease in adult ruminant animals (fever, milk drop and diarrhoea) but readily crosses the placenta of sheep,... Read More about Schmallenberg virus update.

Report of the first veterinary student support workshop (2013)
Journal Article
Kydd, J. H., Cobb, K., Davis, R., Dean, R., Drinkwater, J., Dunham, S., Flynn, R., Gray, C., Grogono-Thomas, R., Hagan, P., Jefferies, A., Jones, M., Ogden, C., Pearson, G., Robinson, N., Rutland, C., Tarlinton, R., Tötemeyer, S., Wason, J., Whittington, R., …Mossop, L. (2013). Report of the first veterinary student support workshop. Veterinary Record, 173(14), 346. https://doi.org/10.1136/vr.101782