Background: Early intervention in psychosis (EIP) services are nationally mandated in England to provide multidisciplinary care to people experiencing first-episode psychosis, which disproportionately affects deprived and ethnic minority youth. Quali... Read More about Implementing and Evaluating a National Integrated Digital Registry and Clinical Decision Support System in Early Intervention in Psychosis Services (Early Psychosis Informatics Into Care): Co-Designed Protocol.
All Outputs (11)
Editorial: Prolonged grief disorder: vulnerability and resilience (2024)
Journal Article
Second-generation antipsychotics and metabolic syndrome: a role for mitochondria (2023)
Journal Article
Psychosis is a known risk factor for developing metabolic syndrome (MetS). The risk is even greater in patients who are taking second-generation antipsychotics (SGAs). SGAs exacerbate metabolic abnormalities and lead to a 3-fold increased risk of sev... Read More about Second-generation antipsychotics and metabolic syndrome: a role for mitochondria.
Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis. (2023)
Journal Article
Oxidative stress may contribute to declining course and poor outcomes in psychosis. However, in vivo Magnetic Resonance Spectroscopy studies yield disparate results due to clinical stage, sample demographics, neuroanatomical focus, sample size, and a... Read More about Measurement of brain glutathione with magnetic Resonance spectroscopy in Schizophrenia-Spectrum disorders - A systematic review and Meta-Analysis..
The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning (2021)
Journal Article
Introduction: The increasing evidence of SARS-CoV-2 impact on the central nervous system (CNS) raises key questions on its impact for risk of later life cognitive decline, Alzheimer's disease (AD), and other dementia. Methods: The Alzheimer's Associa... Read More about The chronic neuropsychiatric sequelae of COVID-19: The need for a prospective study of viral impact on brain functioning.
Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity (2020)
Journal Article
Magnetoencephalography (MEG) measures magnetic fields generated by synchronised neural current flow and provides direct inference on brain electrophysiology and connectivity, with high spatial and temporal resolution. The movement-related beta decrea... Read More about Motor-related oscillatory activity in schizophrenia according to phase of illness and clinical symptom severity.
Impaired recollection-based episodic memory as a cognitive endophenotype in schizophrenia (2020)
Journal Article
Introduction Patients with schizophrenia show impaired recollection but largely preserved familiarity-based episodic memory. This study was done to clarify the endophenotypic nature of recollection and familiarity-based episodic memory in schizophre... Read More about Impaired recollection-based episodic memory as a cognitive endophenotype in schizophrenia.
Quantifying the core deficit in classical schizophrenia (2020)
Journal Article
In the classical descriptions of schizophrenia, Kraepelin and Bleuler recognised disorganization and impoverishment of mental activity as fundamental symptoms. Their classical descriptions also included a tendency to persisting disability. The psycho... Read More about Quantifying the core deficit in classical schizophrenia.
Glutathione and glutamate in schizophrenia: a 7T MRS study (2018)
Journal Article
© 2018 The Author(s) In schizophrenia, abnormal neural metabolite concentrations may arise from cortical damage following neuroinflammatory processes implicated in acute episodes. Inflammation is associated with increased glutamate, whereas the antio... Read More about Glutathione and glutamate in schizophrenia: a 7T MRS study.