All Outputs (9)
Coffee Consumption and Kidney Function: A Mendelian Randomization Study (2019)
Journal Article
Rationale & Objective Chronic kidney disease (CKD) is a leading cause of morbidity and mortality worldwide, with limited strategies for prevention and treatment. Coffee is a complex mixture of chemicals, and consumption has been associated with mo... Read More about Coffee Consumption and Kidney Function: A Mendelian Randomization Study.
Determinants of change in arterial stiffness over 5 years in early chronic kidney disease (2019)
Journal Article
Background Arterial stiffness is an established and potentially modifiable risk factor for cardiovascular disease, associated with chronic kidney disease. There have been few studies to evaluate progression of arterial stiffness over time or factors... Read More about Determinants of change in arterial stiffness over 5 years in early chronic kidney disease.
Skin autofluorescence: an emerging biomarker in persons with kidney disease (2019)
Journal Article
Purpose of review: Skin autofluorescence (SAF) is a measure of the accumulation of advanced glycation end-products (AGEs) proposed to act as a marker of “cumulative metabolic stress”. This paper discusses mechanisms of AGE formation and reviews publi... Read More about Skin autofluorescence: an emerging biomarker in persons with kidney disease.
Chronic Kidney Disease: call for an age-adapted definition (2019)
Journal Article
Current criteria for the diagnosis of chronic kidney disease (CKD) in adults include persistent signs of kidney damage; for example, increased urine albumin-to-creatinine ratio or a glomerular filtration rate (GFR) below the threshold of 60 mL/min pe... Read More about Chronic Kidney Disease: call for an age-adapted definition.
Peritoneal Ultrafiltration for Heart Failure: Lessons from a Randomised Controlled Trial (2019)
Journal Article
Peritoneal ultrafiltration (PuF) has been employed for severe heart failure (HF), but evidence for its benefit is lacking. The Peritoneal Dialysis for Heart Failure (PDHF) study was a multicenter prospective randomized controlled trial which aimed to... Read More about Peritoneal Ultrafiltration for Heart Failure: Lessons from a Randomised Controlled Trial.
Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease (2019)
Journal Article
Although blood pressure control is a major goal in chronic kidney disease, no worldwide overview of either its achievement or antihypertensive prescriptions is currently available. To evaluate this we compared crude prevalence of uncontrolled blood p... Read More about Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease.
Quantitative assessment of renal structural and functional changes in chronic kidney disease using multi-parametric magnetic resonance imaging (2019)
Journal Article
BACKGROUND: Multi-parametric magnetic resonance imaging (MRI) provides the potential for a more comprehensive non-invasive assessment of organ structure and function than individual MRI measures, but has not previously been comprehensively evaluated... Read More about Quantitative assessment of renal structural and functional changes in chronic kidney disease using multi-parametric magnetic resonance imaging.
Biological variation of measured and estimated glomerular filtration rate in patients with chronic kidney disease (2019)
Journal Article
When assessing changes in glomerular filtration rate (GFR) it is important to differentiate pathological change from intrinsic biological and analytical variation. GFR is measured using complex reference methods (e.g., iohexol clearance). In clinical... Read More about Biological variation of measured and estimated glomerular filtration rate in patients with chronic kidney disease.