Natalia Alencar de Pinho
Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease
Alencar de Pinho, Natalia; Levin, Adeera; Fukagawa, Masafumi; Hoy, Wendy E; Pecoits-Filho, Roberto; Reichel, Helmut; Robinson, Bruce; Kitiyakara, Chagriya; Wang, Jinwei; Eckardt, Kai-Uwe; Jha, Vivekanand; Oh, Kook-Hwan; Sola, Laura; Eder, Susanne; de Borst, Martin; Taal, Maarten; Feldman, Harold I.; Stengel, B�n�dicte
Authors
Adeera Levin
Masafumi Fukagawa
Wendy E Hoy
Roberto Pecoits-Filho
Helmut Reichel
Bruce Robinson
Chagriya Kitiyakara
Jinwei Wang
Kai-Uwe Eckardt
Vivekanand Jha
Kook-Hwan Oh
Laura Sola
Susanne Eder
Martin de Borst
MAARTEN TAAL M.TAAL@NOTTINGHAM.AC.UK
Professor of Medicine
Harold I. Feldman
B�n�dicte Stengel
Abstract
Although blood pressure control is a major goal in chronic kidney disease, no worldwide overview of either its achievement or antihypertensive prescriptions is currently available. To evaluate this we compared crude prevalence of uncontrolled blood pressure among 17 cohort studies, including 34 602 individuals with estimated glomerular filtration rate under 60 ml/min/1.73 m2 and treated hypertension across four continents, and estimated observed to expected prevalence ratios, adjusted for potential confounders. Crude prevalence of blood pressure of 140/90 mm Hg or more varied from 28% to 61% and of blood pressure of 130/80 or more from 54% to 84%. Adjusted prevalence ratios indicated poorer hypertension control than expected in cohorts from European countries, India, and Uruguay, and better control in patients from North American and high-income Asian countries. Four antihypertensive drug classes or more were prescribed to more than 30% of participants in North American and some European cohorts, but this practice was less common elsewhere. Renin angiotensin-aldosterone system inhibitors were the most common antihypertensive drugs, prescribed for 54% to 91% of cohort participants. Differences for other drug classes were much stronger, ranging from 11% to 79% for diuretics, 22% to 70% for beta-blockers, and 27% to 75% for calcium-channel blockers. The confounders studied explain only a part of the international variation in blood pressure control among individuals with chronic kidney disease. Thus, considerable heterogeneity in prescription patterns worldwide calls for further investigation into the impact of different approaches on patient outcomes.
Citation
Alencar de Pinho, N., Levin, A., Fukagawa, M., Hoy, W. E., Pecoits-Filho, R., Reichel, H., …Stengel, B. (2019). Considerable international variation exists in blood pressure control and antihypertensive prescription patterns in chronic kidney disease. Kidney International, 96(4), 983-994. https://doi.org/10.1016/j.kint.2019.04.032
Journal Article Type | Article |
---|---|
Acceptance Date | Apr 22, 2019 |
Online Publication Date | Jul 26, 2019 |
Publication Date | 2019-10 |
Deposit Date | Apr 30, 2019 |
Publicly Available Date | Mar 28, 2024 |
Journal | Kidney International |
Print ISSN | 0085-2538 |
Electronic ISSN | 1523-1755 |
Publisher | Elsevier |
Peer Reviewed | Peer Reviewed |
Volume | 96 |
Issue | 4 |
Pages | 983-994 |
DOI | https://doi.org/10.1016/j.kint.2019.04.032 |
Keywords | CESP; INSERM U1018; Renal and Cardiovascular Epidemiology Team Subject Area: Clinical Nephrology; Epidemiology and Statistics; Hypertension Keywords: chronic kidney disease; ACE Inhibitors; cardiovascular disease; diuretics |
Public URL | https://nottingham-repository.worktribe.com/output/1890940 |
Publisher URL | https://www.sciencedirect.com/science/article/pii/S0085253819305125?via%3Dihub |
Files
International variations in blood pressure control and antihypertensive prescription patterns in chronic kidney disease
(2.5 Mb)
PDF
You might also like
Defining improvement in chronic kidney disease: regression and remission
(2022)
Journal Article
Downloadable Citations
About Repository@Nottingham
Administrator e-mail: digital-library-support@nottingham.ac.uk
This application uses the following open-source libraries:
SheetJS Community Edition
Apache License Version 2.0 (http://www.apache.org/licenses/)
PDF.js
Apache License Version 2.0 (http://www.apache.org/licenses/)
Font Awesome
SIL OFL 1.1 (http://scripts.sil.org/OFL)
MIT License (http://opensource.org/licenses/mit-license.html)
CC BY 3.0 ( http://creativecommons.org/licenses/by/3.0/)
Powered by Worktribe © 2024
Advanced Search