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All Outputs (77)

Women with celiac disease present with fertility problems no more often than women in the general population (2014)
Journal Article

BACKGROUND & AIMS: Studies have associated infertility with celiac disease. However, these included small numbers of women attending infertility specialist services and subsequently screened for celiac disease, and therefore may not have been represe... Read More about Women with celiac disease present with fertility problems no more often than women in the general population.

Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England (2014)
Journal Article

OBJECTIVES: Evidence-based information about adverse birth outcomes and pregnancy complications is crucial when counseling women with celiac disease (CD); however, limited population-based data on such risks exist. We estimated these for pregnant wom... Read More about Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England.

First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study (2014)
Journal Article

BACKGROUND: Despite their widespread use the effects of taking benzodiazepines and non-benzodiazepine hypnotics during pregnancy on the risk of major congenital anomaly (MCA) are uncertain. The objectives were to estimate absolute and relative risks... Read More about First trimester exposure to anxiolytic and hypnotic drugs and the risks of major congenital anomalies: a United Kingdom population-based cohort study.

Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study (2014)
Journal Article

OBJECTIVES: Few studies have quantified the incidence and prevalence of celiac disease (CD) and dermatitis herpetiformis (DH) nationally and regionally by time and age groups. Understanding this epidemiology is crucial for hypothesizing about causes... Read More about Incidence and prevalence of celiac disease and dermatitis herpetiformis in the UK over two decades: population-based study.

Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study (2014)
Journal Article

OBJECTIVE: To estimate risks of major congenital anomaly (MCA) among children of mothers prescribed antidepressants during early pregnancy or diagnosed with depression but without antidepressant prescriptions. DESIGN: Population-based cohort study.... Read More about Maternal depression, antidepressant prescriptions, and congenital anomaly risk in offspring: a population-based cohort study.

Small-Cell Lung Cancer in England: Trends in Survival and Chemotherapy Using the National Lung Cancer Audit (2014)
Journal Article

Background The purpose of this study was to identify trends in survival and chemotherapy use for individuals with small-cell lung cancer (SCLC) in England using the National Lung Cancer Audit (NLCA). Methods We used data from the NLCA database... Read More about Small-Cell Lung Cancer in England: Trends in Survival and Chemotherapy Using the National Lung Cancer Audit.

The direct medical costs of epilepsy in children and young people: a population-based study of health resource utilisation (2014)
Journal Article

We described the health resource utilisation (HRU) and associated direct medical costs of managing epilepsy in children and young people (CYP) using population-level data from the United Kingdom. The study cohort were CYP born between 1988 and 20... Read More about The direct medical costs of epilepsy in children and young people: a population-based study of health resource utilisation.

Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England (2013)
Journal Article

Objective: To examine the potential for preventing venous thromboembolism during and after antepartum hospital admissions in pregnant women. Design: Cohort study using linked primary (Clinical Practice Research Datalink) and secondary (Hospital E... Read More about Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England.

Risk factors for scald injury in children under 5 years of age: a case–control study using routinely collected data (2013)
Journal Article

Scald injury is common, accounting for half of all burns in pre-school children. Most scalds are preventable and health professionals can play an important role in targeting interventions to those at greatest risk. However, the potential for routinel... Read More about Risk factors for scald injury in children under 5 years of age: a case–control study using routinely collected data.

Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications (2013)
Journal Article

Background & aims: Concerns persist about the risk of major congenital anomalies in children of women with inflammatory bowel disease (IBD), and whether medication use affects risk. We assessed these risks, and variations in use of medications by wom... Read More about Limited risks of major congenital anomalies in children of mothers with IBD and effects of medications.

Completeness of maternal smoking status recording during pregnancy in United Kingdom primary care data (2013)
Journal Article

Background: Given the health impacts of smoking during pregnancy and the opportunity for primary healthcare teams to encourage pregnant smokers to quit, we assessed the completeness of gestational smoking status recording in primary care data and inv... Read More about Completeness of maternal smoking status recording during pregnancy in United Kingdom primary care data.

The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis (2013)
Journal Article

Background: Recent linkage between primary and secondary care data has provided valuable information for studying heath outcomes that may initially present in different health care settings. The aim of this study was therefore, twofold: to use linke... Read More about The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis.

Independent risk factors for injury in pre-school children: three population-based nested case-control studies using routine primary care data (2012)
Journal Article

Background: Injuries in childhood are largely preventable yet an estimated 2,400 children die every day because of injury and violence. Despite this, the factors that contribute to injury occurrence have not been quantified at the population scale us... Read More about Independent risk factors for injury in pre-school children: three population-based nested case-control studies using routine primary care data.