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All Outputs (122)

Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study (2019)
Journal Article
Henry, M., Abdul-Sultan, A., Walker, A., West, J., & Humes, D. (2019). Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study. Digestive Surgery, 37(1), 32-38. https://doi.org/10.1159/000496435

Background:
This study aimed to identify burden and risk of VTE associated with cholecystectomy in England.

Methods:
An historical cohort study of cholecystectomy patients from 2001-2011 was undertaken using linked primary (Clinical Practice... Read More about Duration and Magnitude of Postoperative Risk of Venous Thromboembolism after Cholecystectomy: A Population-Based Cohort Study.

Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis (2018)
Journal Article
Otete, H., Fleming, K. M., West, J., & Orton, E. (2019). Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis. Alcohol and Alcoholism, 54(2), 131–138. https://doi.org/10.1093/alcalc/agy085

Aims: This study aimed to describe healthcare utilisation, morbidities and monitoring of alcohol use in patients prior to a diagnosis of alcoholic psychosis in order to inform the early identification of patients at risk.

Method: Using linked gene... Read More about Healthcare utilisation, morbidities and alcohol use monitoring prior to alcoholic psychosis diagnosis.

Mortality in people with coeliac disease: long-term follow-up from a Scottish cohort (2018)
Journal Article
Quarpong, W., Card, T. R., West, J., Solaymani-Dodaran, M., Logan, R. F., & Grainge, M. J. (2019). Mortality in people with coeliac disease: long-term follow-up from a Scottish cohort. United European Gastroenterology Journal, 7(3), 377-387. https://doi.org/10.1177/2050640618814662

Background: Few studies have determined the very long-term mortality risks in adult and childhood-diagnosed coeliac disease.

Objective: We quantified mortality risks in coeliac disease and determined whether age at diagnosis, or time following di... Read More about Mortality in people with coeliac disease: long-term follow-up from a Scottish cohort.

Changing autonomy in operative experience through UK general surgery training: a national cohort study (2018)
Journal Article
Elsey, E. J., Griffiths, G., West, J., & Humes, D. J. (2019). Changing autonomy in operative experience through UK general surgery training: a national cohort study. Annals of Surgery, 269(3), 399-406. https://doi.org/10.1097/sla.0000000000003032

Objectives:To determine the operative experience of UK general surgery trainees and assess the changing procedural supervision and acquisition of competency assessments through the course of training.

Background Summary Data: Competency assessment... Read More about Changing autonomy in operative experience through UK general surgery training: a national cohort study.

Time out of general surgery specialty training in the UK: a national database study (2018)
Journal Article
Elsey, E. J., West, J., Griffiths, G., & Humes, D. J. (2019). Time out of general surgery specialty training in the UK: a national database study. Journal of Surgical Education, 76(1), 55-64. https://doi.org/10.1016/j.jsurg.2018.06.011

Objective:General surgery specialty training in the UK takes 6 years and allows trainees to take time out of training. Studies from the USA have highlighted an increasing trend for taking time out of surgical training for research. This study aimed t... Read More about Time out of general surgery specialty training in the UK: a national database study.

Injury among children and young people with and without attention deficit-hyperactivity disorder in the community: the risk of fractures, thermal injuries and poisonings (2018)
Journal Article
Prasad, V., West, J., Sayal, K., & Kendrick, D. (2018). Injury among children and young people with and without attention deficit-hyperactivity disorder in the community: the risk of fractures, thermal injuries and poisonings. Child: Care, Health and Development, 44(6), 871-878. https://doi.org/10.1111/cch.12591

Background: Injuries commonly cause morbidity and mortality in children and young people (CYP). Attention deficit-hyperactivity disorder (ADHD) is the commonest neurobehavioural disorder in CYP and is associated with increased injury risk. However, l... Read More about Injury among children and young people with and without attention deficit-hyperactivity disorder in the community: the risk of fractures, thermal injuries and poisonings.

Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data (2018)
Journal Article
Otete, H. E., Deleuran, T., Fleming, K. M., Card, T. R., Aithal, G. P., Jepsen, P., & West, J. (2018). Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data. Journal of Hepatology, 69(3), 697-704. https://doi.org/10.1016/j.jhep.2018.04.002

Background & aims: Cirrhosis is a risk factor for osteoporosis and fractures. However, little is known of the actual risk of hip fractures in patients with alcoholic cirrhosis. Using linked primary and secondary care data from the English and Danish... Read More about Hip fracture risk in patients with alcoholic cirrhosis: a population-based study using English and Danish data.

Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation (2018)
Journal Article
Prasad, V., West, J., Kendrick, D., & Sayal, K. (2019). Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation. Archives of Disease in Childhood, 104(8), 802-805. https://doi.org/10.1136/archdischild-2017-314470

Background: In England, there is a discrepancy between the prevalence of Attention-deficit/hyperactivity disorder (ADHD) ascertained from medical records and community surveys. There is also a lack of data on variation in recorded prevalence by depri... Read More about Attention-deficit/hyperactivity disorder: variation by socio-economic deprivation.

A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink (2018)
Journal Article
Crooks, C. J., West, J., & Jepson, P. (2018). A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink. Clinical Epidemiology, 2018:10, https://doi.org/10.2147/CLEP.S147535

Purpose: The CirCom score has been developed from Danish data as a specific measure of comorbidity for cirrhosis to predict all-cause mortality. We compared its performance with the Charlson Comorbidity Index (CCI) in an English cirrhosis population.... Read More about A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink.

Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study (2018)
Journal Article
Humes, D., Abdul-Sultan, A., Walker, A. J., Ludvigsson, J. F., & West, J. (2018). Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study. Hernia, 22(3), 447-453. https://doi.org/10.1007/s10029-017-1716-6

Purpose
Little is known regarding the magnitude and timing of the risk of VTE following inguinal hernia surgery. We aimed to determine the absolute and relative rates of venous thromboembolism (VTE) following planned inguinal hernia repair.

Metho... Read More about Duration and magnitude of postoperative risk of venous thromboembolism after planned inguinal hernia repair in men: a population-based cohort study.

Liver cirrhosis in England--an observational study: are we measuring its burden occurrence correctly? (2017)
Journal Article
Ratib, S., West, J., & Fleming, K. M. (2017). Liver cirrhosis in England--an observational study: are we measuring its burden occurrence correctly?. BMJ Open, 7(7), Article e013752. https://doi.org/10.1136/bmjopen-2016-013752

Objectives: Mortality due to liver disease (of which cirrhosis is the end‐stage) is increasing more than any other chronic condition in the UK. This study aims to demonstrate that (i) exclusive reliance on mortality rates may not reveal the true burd... Read More about Liver cirrhosis in England--an observational study: are we measuring its burden occurrence correctly?.

Mineral status in canine medial coronoid process disease: a cohort study using analysis of hair by mass spectrometry (2017)
Journal Article
Davies, M., West, J., Williams, C., & Gardner, D. S. (in press). Mineral status in canine medial coronoid process disease: a cohort study using analysis of hair by mass spectrometry. Veterinary Record, 180(18), https://doi.org/10.1136/vr.103953

In several species, developmental skeletal diseases involving abnormal endochondral ossification have been associated with imbalanced mineral intake. Hair analysis reflects long-term mineral status. To determine the mineral content of hair from dogs... Read More about Mineral status in canine medial coronoid process disease: a cohort study using analysis of hair by mass spectrometry.

Risk of hepatocellular carcinoma among individuals with different aetiologies of cirrhosis: a population-based cohort study (2017)
Journal Article
West, J., Card, T. R., Aithal, G. P., & Fleming, K. M. (2017). Risk of hepatocellular carcinoma among individuals with different aetiologies of cirrhosis: a population-based cohort study. Alimentary Pharmacology and Therapeutics, 45(7), 983-990. https://doi.org/10.1111/apt.13961

Background: Among patients with cirrhosis, only those determined to be at risk for hepatocellular carcinoma (HCC) should undergo surveillance. However, little is known about how different aetiologies of cirrhosis affect risk for HCC.
Aim: To quantif... Read More about Risk of hepatocellular carcinoma among individuals with different aetiologies of cirrhosis: a population-based cohort study.

Meta-analysis of operative experiences of general surgery trainees during training (2016)
Journal Article
Elsey, E., Griffiths, G., Humes, D., & West, J. (in press). Meta-analysis of operative experiences of general surgery trainees during training. British Journal of Surgery, 104(1), https://doi.org/10.1002/bjs.10396

BACKGROUND: General surgical training curricula around the world set defined operative numbers to be achieved before completion of training. However, there are few studies reporting total operative experience in training. This systematic review aimed... Read More about Meta-analysis of operative experiences of general surgery trainees during training.

Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study (2016)
Journal Article
Sultan, A. A., West, J., Grainge, M. J., Riley, R. D., Tata, L. J., Stephansson, O., Fleming, K. M., Nelson-Piercy, C., & Ludvigsson, J. F. (2016). Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study. BMJ, 355(i6253), https://doi.org/10.1136/bmj.i6253

Objective: To develop and validate a risk prediction model for venous thromboembolism in the first six weeks after delivery (early postpartum).

Design: Cohort study.

Setting: Records from England based Clinical Practice Research Datalink (CPRD)... Read More about Development and validation of risk prediction model for venous thromboembolism in postpartum women: multinational cohort study.

The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England (2016)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2016). The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England. PLoS ONE, 11(10), 1-16. https://doi.org/10.1371/journal.pone.0165507

Background: We have assessed whether the linkage between routine primary and secondary care records provided an opportunity to develop an improved population based co-morbidity score with the combined information on co-morbidities from both health ca... Read More about The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England.

Adverse pregnancy outcomes among women with inflammatory bowel disease: a population based study from England (2016)
Journal Article
Abdul Sultan, A., West, J., Ban, L., Humes, D., Tata, L. J., Fleming, K. M., Nelson-Piercy, C., & Card, T. R. (2016). Adverse pregnancy outcomes among women with inflammatory bowel disease: a population based study from England. Inflammatory Bowel Diseases, 22(7), 1621-1630. https://doi.org/10.1097/MIB.0000000000000802

Background: There is limited contemporary population based evidence on adverse birth outcomes and pregnancy related complications for women with inflammatory bowel disease (IBD). This study provides such estimates of these risks and assesses variatio... Read More about Adverse pregnancy outcomes among women with inflammatory bowel disease: a population based study from England.

The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study (2016)
Journal Article
Zingone, F., Abdul Sultan, A., Crooks, C. J., Tata, L. J., Ciacci, C., & West, J. (in press). The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study. Alimentary Pharmacology and Therapeutics, 44(1), https://doi.org/10.1111/apt.13652

Background: Patients with coeliac disease are considered as individuals for whom pneumococcal vaccination is advocated.

Aim: To quantify the risk of community-acquired pneumonia among patients with coeliac disease, assessing whether vaccination ag... Read More about The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study.

Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults (2016)
Journal Article
Humes, D., Walker, A. J., Hunt, B., Sultan, A. A., Ludvigsson, J. F., & West, J. (2016). Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults. British Journal of Surgery, 103(4), 443-450. https://doi.org/10.1002/bjs.10091

BACKGROUND: Appendicectomy is the commonest intra-abdominal emergency surgical procedure, and little is known regarding the magnitude and timing of the risk of venous thromboembolism (VTE) after surgery. This study aimed to determine absolute and rel... Read More about Risk of symptomatic venous thromboembolism following emergency appendicectomy in adults.