All Outputs (20)

Food biotechnology (2020)
Journal Article

We investigate recent advances in the Chemical Engineering aspects of food structuring agents and macronutrients: carbohydrates, proteins and lipids, and also the fate of food upon ingestion. Prebiotic effects on host-microbe interactions enable impr... Read More about Food biotechnology.

Phage control of Campylobacter jejuni in chickens does not produce collateral effects on the gut microbiota (2019)
Journal Article

Bacteriophage biocontrol to reduce Campylobacter jejuni levels in chickens can reduce human exposure and disease acquired through the consumption of contaminated poultry products.Investigating changes in the chicken microbiota during phage treatment... Read More about Phage control of Campylobacter jejuni in chickens does not produce collateral effects on the gut microbiota.

FlhF(T368A) modulates motility in the bacteriophage carrier state of Campylobacter jejuni (2018)
Journal Article

© 2018 The Authors. Molecular Microbiology Published by John Wiley & Sons Ltd. The carrier state is an alternative bacteriophage life cycle by which virulent bacteriophage can persist in association with host bacteria. Campylobacter jejuni carrier... Read More about FlhF(T368A) modulates motility in the bacteriophage carrier state of Campylobacter jejuni.

Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients (2018)
Journal Article

The recorded growth in infection by multidrug resistant bacteria necessitates prompt efforts towards developing alternatives to antibiotics, such as bacteriophage therapy. Immuno-compromised patients with diabetes mellitus are particularly prone to f... Read More about Bacteriophage ZCKP1: a potential treatment for Klebsiella pneumoniae isolated from diabetic foot patients.

The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens (2018)
Journal Article

Background Campylobacters are an unwelcome member of the poultry gut microbiota in terms of food safety. The objective of this study was to compare the microbiota, inflammatory responses, and zootechnical parameters of broiler chickens not exposed t... Read More about The effect of the timing of exposure to Campylobacter jejuni on the gut microbiome and inflammatory responses of broiler chickens.

Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli (2017)
Journal Article

Campylobacter contaminated poultry meat is a major source of human foodborne illness. Campylobacter coli strain OR12 is a robust colonizer of chickens that was previously shown to outcompete and displace other Campylobacter strains from the chicken’s... Read More about Characterisation of aerotolerant forms of a robust chicken colonizing Campylobacter coli.

The minor flagellin of Campylobacter jejuni (FlaB) confers defensive properties against bacteriophage infection (2016)
Journal Article

A screen of bacteriophages infecting a panel of Campylobacter jejuni PT14 gene knock-out mutants identified a role for the minor flagellin encoded by the flaB gene, in the defense of the host against CP8unalikevirus bacteriophage CP_F1 infection. Ina... Read More about The minor flagellin of Campylobacter jejuni (FlaB) confers defensive properties against bacteriophage infection.

Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol (2016)
Journal Article

Consumption of foods containing chicken liver has been associated with Campylobacter enteritis. Campylobacters can contaminate the surface of livers post-mortem but can also arise through systemic infection of colonising bacteria in live birds. The u... Read More about Campylobacters and their bacteriophages from chicken liver: the prospect for phage biocontrol.

The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized (2016)
Journal Article

Starches from three organically produced cultivars of potato tuber (Lady Rosetta, Spunta and Voyager) have been studied in relation to (i) acrylamide production (ii) macromolecular integrity after frying with extra virgin olive oil, soybean oil and c... Read More about The effect of thermal processing in oil on the macromolecular integrity and acrylamide formation from starch of three potato cultivars organically fertilized.

The bacteriophage carrier state of Campylobacter jejuni features changes in host non-coding RNAs and the acquisition of new host-derived CRISPR spacer sequences (2016)
Journal Article

Incorporation of self-derived CRISPR DNA protospacers in Campylobacter jejuni PT14 occurs in the presence of bacteriophages encoding a CRISPR-like Cas4 protein. This phenomenon was evident in carrier state infections where both bacteriophages and ho... Read More about The bacteriophage carrier state of Campylobacter jejuni features changes in host non-coding RNAs and the acquisition of new host-derived CRISPR spacer sequences.

Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168 (2016)
Journal Article

Phase-variable restriction-modification systems are a feature of a diverse range of bacterial species. Stochastic, reversible switches in expression of the methyltransferase produces variation in methylation of specific sequences. Phase-variable meth... Read More about Phase variation of a Type IIG restriction-modification enzyme alters site-specific methylation patterns and gene expression in Campylobacter jejuni strain NCTC11168.

Filamentation of Campylobacter in broth cultures (2015)
Journal Article

The transition from rod to filamentous cell morphology has been identified as a response to stressful conditions in many bacterial species and has been ascribed to confer certain survival advantages. Filamentation of Campylobacter jejuni was demonstr... Read More about Filamentation of Campylobacter in broth cultures.

Host adaption to the bacteriophage carrier state of Campylobacter jejuni (2015)
Journal Article

The carrier state of the foodborne pathogen Campylobacter jejuni represents an alternative life cycle whereby virulent bacteriophage can persistent in association with host bacteria without commitment to lysogeny. Host bacteria exhibit significant ph... Read More about Host adaption to the bacteriophage carrier state of Campylobacter jejuni.

Xylan degrading enzymes from fungal sources (2015)
Journal Article

Fungi have the ability to degrade xylan as the major component of plant cell wall hemicellulose. Fungi have evolved batteries of xylanolytic enzymes that concertedly act to depolymerise xylan backbones decorated with variable carbohydrate branches. A... Read More about Xylan degrading enzymes from fungal sources.

Campylobacter jejuni acquire new host-derived CRISPR spacers when in association with bacteriophages harboring a CRISPR-like Cas4 protein (2015)
Journal Article

Campylobacter jejuni is a worldwide cause of human diarrhoeal disease. Clustered Repetitively Interspaced Palindromic Repeats (CRISPRs) and associated proteins allow Bacteria and Archaea to evade bacteriophage and plasmid infection. Type II CRISPR sy... Read More about Campylobacter jejuni acquire new host-derived CRISPR spacers when in association with bacteriophages harboring a CRISPR-like Cas4 protein.

Characterisation of a recombinant ?-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris (2014)
Journal Article

β-xylosidases catalyse the hydrolysis of short chain xylooligosaccharides from their non-reducing ends into xylose. In this study we report the heterologous expression of Aspergillus oryzae β-xylosidase (XylA) in Pichia pastoris under the control of... Read More about Characterisation of a recombinant ?-xylosidase (xylA) from Aspergillus oryzae expressed in Pichia pastoris.

Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni (2014)
Journal Article

Members of the genus Campylobacter are frequently responsible for human enteric disease, often through consumption of contaminated poultry products. Bacteriophages are viruses that have the potential to control pathogenic bacteria, but understanding... Read More about Alternative bacteriophage life cycles: the carrier state of Campylobacter jejuni.

Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens (2005)
Journal Article

Colonization of broiler chickens by the enteric pathogen Campylobacter jejuni is widespread and difficult to prevent. Bacteriophage therapy is one possible means by which this colonization could be controlled, thus limiting the entry of campylobacter... Read More about Bacteriophage therapy to reduce Campylobacter jejuni colonization of broiler chickens.

Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca (2005)
Journal Article

Campylobacter jejuni and Campylobacter-specific bacteriophage were enumerated from broiler chicken ceca selected from 90 United Kingdom flocks (n = 205). C. jejuni counts in the presence of bacteriophage (mean log10 5.1 CFU/g) were associated with a... Read More about Correlation of Campylobacter bacteriophage with reduced presence of hosts in broiler chicken ceca.

Isolation and characterization of Campylobacter bacteriophages from retail poultry (2003)
Journal Article

The ability of phages to survive processing is an important aspect of their potential use in the biocontrol of Campylobacter in poultry production. To this end, we have developed a procedure to recover Campylobacter bacteriophages from chilled and fr... Read More about Isolation and characterization of Campylobacter bacteriophages from retail poultry.