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Cord pilot trial, comparing alternative policies for timing of cord clamping before 32 weeks gestation: follow-up for women up to one year (2019)
Journal Article
Bradshaw, L., Sawyer, A., Armstrong-Buisseret, L., Mitchell, E., Ayers, S., & Duley, L. (2019). Cord pilot trial, comparing alternative policies for timing of cord clamping before 32 weeks gestation: follow-up for women up to one year. BMC Pregnancy and Childbirth, 19, Article 78. https://doi.org/10.1186/s12884-019-2223-9

Background The Cord Pilot Trial compared two alternative policies for cord clamping at very preterm birth at eight UK maternity units: clamping after at least 2 min and immediate neonatal care (if needed) with cord intact, or clamping within 20 s an... Read More about Cord pilot trial, comparing alternative policies for timing of cord clamping before 32 weeks gestation: follow-up for women up to one year.

On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling (2018)
Journal Article
Falcke, M., Moein, M., Tilunaite, A., Thul, R., & Skupin, A. (2018). On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling. Chaos, 28(4), Article 045115. https://doi.org/10.1063/1.5021073

The correspondence between mathematical structures and experimental systems is the basis of the generalizability of results found with specific systems, and is the basis of the predictive power of theoretical physics. While physicists have confidence... Read More about On the phase space structure of IP3 induced Ca2+ signalling and concepts for predictive modeling.

The portormin (dunbeath) runestone (2016)
Journal Article
Findell, M. (2016). The portormin (dunbeath) runestone. Futhark: International Journal of Runic Studies, 6, 153-170

A stone with a short runic inscription was discovered on the beach at Portormin Harbour in Dunbeath, Caithness, in 1996. The find attracted some press attention at the time, but has been largely ignored by the runological com­mu­nity amid doubts over... Read More about The portormin (dunbeath) runestone.

ERiSA: building emotionally realistic social game-agents companions (2014)
Journal Article
Chowanda, A., Blanchfield, P., Flintham, M. D., & Valstar, M. (in press). ERiSA: building emotionally realistic social game-agents companions. Lecture Notes in Artificial Intelligence, 8637, https://doi.org/10.1007/978-3-319-09767-1_16

We propose an integrated framework for social and emotional game-agents to enhance their believability and quality of interaction, in particular by allowing an agent to forge social relations and make appropriate use of social signals. The framework... Read More about ERiSA: building emotionally realistic social game-agents companions.

The Malthusian Paradox: performance in an alternate reality game (2014)
Journal Article
Evans, E., Flintham, M., & Martindale, S. (2014). The Malthusian Paradox: performance in an alternate reality game. Personal and Ubiquitous Computing, 18(7), https://doi.org/10.1007/s00779-014-0762-7

The Malthusian Paradox is a transmedia alternate reality game (ARG) created by artists Dominic Shaw and Adam Sporne played by 300 participants over three months. We explore the design of the game, which cast players as agents of a radical organisatio... Read More about The Malthusian Paradox: performance in an alternate reality game.

Understanding mass participatory pervasive computing systems for environmental campaigns (2013)
Journal Article
Chamberlain, A., Paxton, M., Glover, K., Flintham, M., Price, D., Benford, S., …Greenhalgh, C. (2014). Understanding mass participatory pervasive computing systems for environmental campaigns. Personal and Ubiquitous Computing, 18(7), https://doi.org/10.1007/s00779-013-0756-x

Participate was a 3-year collaboration between industry and academia to explore how mobile, Web and broadcast technologies could combine to deliver environ- mental campaigns. In a series of pilot projects, schools used mobile sensors to enhance scien... Read More about Understanding mass participatory pervasive computing systems for environmental campaigns.

Fundamental properties of Ca²⁺ signals (2011)
Journal Article
Thurley, K., Skupin, A., Thul, R., & Falcke, M. (2011). Fundamental properties of Ca²⁺ signals. BBA - General Subjects, 1820(8), https://doi.org/10.1016/j.bbagen.2011.10.007

Background Ca²⁺ is a ubiquitous and versatile second messenger that transmits information through changes of the cytosolic Ca²⁺ concentration. Recent investigations changed basic ideas on the dynamic character of Ca²⁺ signals and challenge tradition... Read More about Fundamental properties of Ca²⁺ signals.

Cardiac cell modelling: observations from the heart of the cardiac physiome project (2011)
Journal Article
Fink, M., Niederer, S. A., Cherry, E. M., Fenton, F. H., Koivumäki, J. T., Seemann, G., …Smith, N. P. (2011). Cardiac cell modelling: observations from the heart of the cardiac physiome project. Progress in Biophysics and Molecular Biology, 104(1-3), https://doi.org/10.1016/j.pbiomolbio.2010.03.002

In this manuscript we review the state of cardiac cell modelling in the context of international initiatives such as the IUPS Physiome and Virtual Physiological Human Projects, which aim to integrate computational models across scales and physics. In... Read More about Cardiac cell modelling: observations from the heart of the cardiac physiome project.

Towards a predictive model of Ca²⁺ puffs (2009)
Journal Article
Thul, R., Thurley, K., & Falcke, M. (2009). Towards a predictive model of Ca²⁺ puffs. Chaos, 19, https://doi.org/10.1063/1.3183809

We investigate key characteristics of Ca²⁺ puffs in deterministic and stochastic frameworks that all incorporate the cellular morphology of IP[subscript]3 receptor channel clusters. In a first step, we numerically study Ca²⁺ liberation in a three dim... Read More about Towards a predictive model of Ca²⁺ puffs.

Waiting time distributions for clusters of complex molecules (2007)
Journal Article
Thul, R., & Falcke, M. (2007). Waiting time distributions for clusters of complex molecules. EPL, 79(3), https://doi.org/10.1209/0295-5075/79/38003

Waiting time distributions are in the core of theories for a large variety of subjects ranging from the analysis of patch clamp records to stochastic excitable systems. Here, we present a novel exact method for the calculation of waiting time distrib... Read More about Waiting time distributions for clusters of complex molecules.

Frequency of elemental events of intracellular Ca²⁺ dynamics (2006)
Journal Article
Thul, R., & Falcke, M. (2006). Frequency of elemental events of intracellular Ca²⁺ dynamics. Physical Review E, 73, Article 061923. https://doi.org/10.1103/PhysRevE.73.061923

The dynamics of intracellular Ca²⁺ is driven by random events called Ca²⁺ puffs, in which Ca²⁺ is liberated from intracellular stores. We show that the emergence of Ca²⁺ puffs can be mapped to an escape process. The mean first passage times that corresp... Read More about Frequency of elemental events of intracellular Ca²⁺ dynamics.

Release currents of IP? receptor channel clusters and concentration profiles (2004)
Journal Article
Thul, R., & Falcke, M. (2004). Release currents of IP? receptor channel clusters and concentration profiles. Biophysical Journal, 86(5),

We simulate currents and concentration profiles generated by Ca2+ release from the endoplasmic reticulum (ER) to the cytosol through IP3 receptor channel clusters. Clusters are described as conducting pores in the lumenal membrane with a diameter f... Read More about Release currents of IP? receptor channel clusters and concentration profiles.

Stability of membrane bound reactions (2004)
Journal Article
Thul, R., & Falcke, M. (2004). Stability of membrane bound reactions. Physical Review Letters, 93(18), https://doi.org/10.1103/+PhysRevLet+t.93.188103

We present a novel approach to the dynamics of reactions of diffusing chemical species with species fixed in space e.g. by binding to a membrane. The non-diffusing reaction partners are clustered in areas with a diameter smaller than the diffusion length... Read More about Stability of membrane bound reactions.