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Functional performance of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold: a pre-clinical in vitro tribological study (2024)
Journal Article

Osteochondral grafts are used for repair of focal osteochondral lesions. Autologous grafts are the gold standard treatment; however, limited graft availability and donor site morbidity restrict use. Therefore, there is a clinical need for different g... Read More about Functional performance of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold: a pre-clinical in vitro tribological study.

Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation (2022)
Journal Article

Phosphate-based glasses (PBGs) are promising materials for bone repair and regeneration as they can be formulated to be compositionally similar to the inorganic components of bone. Alterations to the PBG formulation can be used to tailor their degrad... Read More about Developing Porous Ortho- and Pyrophosphate-Containing Glass Microspheres; Structural and Cytocompatibility Characterisation.

Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold (2022)
Journal Article

An innovative approach was developed to engineer a multi-layered chitosan scaffold for osteochondral defect repair. A combination of freeze drying and porogen-leaching out methods produced a porous, bioresorbable scaffold with a distinct gradient of... Read More about Development and in vitro assessment of a bi-layered chitosan-nano-hydroxyapatite osteochondral scaffold.

Evaluating the cytotoxicity of Ge–Sb–Se chalcogenide glass optical fibres on 3T3 mouse fibroblasts (2021)
Journal Article

In vivo cancer detection based on the mid-infrared molecular fingerprint of tissue is promising for the fast diagnosis and treatment of suspected cancer patients. Few materials are mid-infrared transmissive, even fewer, which can be converted into fu... Read More about Evaluating the cytotoxicity of Ge–Sb–Se chalcogenide glass optical fibres on 3T3 mouse fibroblasts.

In-vitro cell interaction and apatite forming ability in simulated body fluid of ICIE16 and 13-93 bioactive glass coatings deposited by an emerging suspension high velocity oxy fuel (SHVOF) thermal spray (2020)
Journal Article

ICIE16 and 13-93 bioactive glasses have been proposed as alternative chemically stable compositions in physiological fluid keeping bioactivity comparable to Bioglass®. ICIE16 and 13-93 bioactive glasses coatings were produced via an emerging suspensi... Read More about In-vitro cell interaction and apatite forming ability in simulated body fluid of ICIE16 and 13-93 bioactive glass coatings deposited by an emerging suspension high velocity oxy fuel (SHVOF) thermal spray.

Production of High Silicon-Doped Hydroxyapatite Thin Film Coatings via Magnetron Sputtering: Deposition, Characterisation, and In Vitro Biocompatibility (2020)
Journal Article

In recent years, it has been found that small weight percent additions of silicon to HA can be used to enhance the initial response between bone tissue and HA. A large amount of research has been concerned with bulk materials, however, only recently... Read More about Production of High Silicon-Doped Hydroxyapatite Thin Film Coatings via Magnetron Sputtering: Deposition, Characterisation, and In Vitro Biocompatibility.

Preclinical biological and physicochemical evaluation of two-photon engineered 3D biomimetic copolymer scaffolds for bone healing (2020)
Journal Article

A major challenge in orthopedics is the repair of large non-union bone fractures. A promising therapy for this indication is the use of biodegradable bioinspired biomaterials that stabilize the fracture site, relieve pain and initiate bone formation... Read More about Preclinical biological and physicochemical evaluation of two-photon engineered 3D biomimetic copolymer scaffolds for bone healing.

In vitro cellular testing of Strontium/Calcium substituted phosphate glass discs and microspheres shows potential for bone regeneration (2019)
Journal Article

Phosphate glasses (PBG) are ideal materials for regenerative medicine strategies since their composition, degradation rates and ion release profiles can easily be controlled. Strontium has previously been found to simultaneously affect bone resorptio... Read More about In vitro cellular testing of Strontium/Calcium substituted phosphate glass discs and microspheres shows potential for bone regeneration.

Computational mechanical characterization of geometrically transformed Schwarz P lattice tissue scaffolds fabricated via two photon polymerization (2PP) (2018)
Journal Article

Schwarz P unit cell-based tissue scaffolds comprised of poly(D,L-lactide-co-caprolactone)(PLCL) fabricated via the additive manufacturing technique, two-photon polymerisation (2PP) were found to undergo geometrical transformations from the original i... Read More about Computational mechanical characterization of geometrically transformed Schwarz P lattice tissue scaffolds fabricated via two photon polymerization (2PP).

Performance of multiphase scaffolds for bone repair based on two-photon polymerized poly(d,l-lactide-co-?-caprolactone), recombinamers hydrogel and nano-HA (2018)
Journal Article

Multiphase hybrids were fabricated from poly(d,l-lactide-co-ɛ-caprolactone) (PLCL) copolymer scaffolds impregnated with silk-elastin-like recombinamers (SELRs) hydrogel containing 2 wt% hydroxyapatite nanoparticles (nHA). The PLCL scaffolds, triply-p... Read More about Performance of multiphase scaffolds for bone repair based on two-photon polymerized poly(d,l-lactide-co-?-caprolactone), recombinamers hydrogel and nano-HA.

In vitro degradation and mechanical properties of PLA-PCL copolymer unit cell scaffolds generated by two-photon polymerization (2016)
Journal Article

© 2016 IOP Publishing Ltd. The manufacture of 3D scaffolds with specific controlled porous architecture, defined microstructure and an adjustable degradation profile was achieved using two-photon polymerization (TPP) with a size of 2 × 4 × 2 mm3. Sca... Read More about In vitro degradation and mechanical properties of PLA-PCL copolymer unit cell scaffolds generated by two-photon polymerization.