Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma

Rutland, Catrin S.; Cockcroft, James M.; Lothion-Roy, Jennifer; Harris, Anna E.; Jeyapalan, Jennie N.; Simpson, Siobhan; Alibhai, Aziza; Bailey, Clara; Ballard-Reisch, Alyssa C.; Rizvanov, Albert A.; Dunning, Mark D.; de Brot, Simone; Mongan, Nigel P.

doi:10.3389/fvets.2021.704598

The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer (2022)
Journal Article

Prostate cancer (PCa) is a leading cause of cancer-related deaths and is driven by aberrant androgen receptor (AR) signalling. For this reason, androgen deprivation therapies (ADTs) that suppress androgen-induced PCa progression either by preventing... Read More about The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer.

Anatomy, histology, development and functions of Ossa cordis: A review (2022)
Journal Article

This systematic review highlights the similarities and variations in Ossa cordis prevalence, histology and anatomical location between differing veterinary species and in humans. In addition, it also identifies associated factors such as aging and ca... Read More about Anatomy, histology, development and functions of Ossa cordis: A review.

Evaluation of Current and Future Diagnostic and Prognostic Techniques for Traumatic Pericarditis in Cattle (2022)
Book Chapter

Pericarditis in cattle can be classified as traumatic pericarditis (TP), idiopathic haemorrhagic, secondary to neoplasia or septic pericarditis due to haematogenous spread of organisms, such as Colibacilli or Pasturella. In cattle, pericardial diseas... Read More about Evaluation of Current and Future Diagnostic and Prognostic Techniques for Traumatic Pericarditis in Cattle.

Artificial Microvesicles: New Perspective on Healing Tendon Wounds (2022)
Journal Article

Tendons have a limited capacity to repair both naturally and following clinical interventions. Damaged tissue often presents with structural and functional differences, adversely affecting animal performance, mobility, health, and welfare. Advances i... Read More about Artificial Microvesicles: New Perspective on Healing Tendon Wounds.

Salivary Gland Adaptation to Dietary Inclusion of Hydrolysable Tannins in Boars (2022)
Journal Article

The ingestion of hydrolysable tannins as a potential nutrient to reduce boar odor in entire males results in the significant enlargement of parotid glands (parotidomegaly). The objective of this study was to characterize the effects of different leve... Read More about Salivary Gland Adaptation to Dietary Inclusion of Hydrolysable Tannins in Boars.

Isolation, culturing and 3D bioprinting of equine myoblasts (2022)
Journal Article

Isolating and culturing myoblasts is essential for techniques such as tissue regeneration and in vitro meat production. This research describes a protocol to isolate primary myoblasts from skeletal muscle of an adult horse. The equine primary myoblas... Read More about Isolation, culturing and 3D bioprinting of equine myoblasts.

Impact of COVID-19 on student attainment and pedagogical needs when undertaking independent scientific research (2022)
Journal Article

Research is often an essential component of completing a veterinary medicine degree, with universities worldwide aiming to teach students a variety of techniques and general research comprehension and skills. As universities worldwide navigated the C... Read More about Impact of COVID-19 on student attainment and pedagogical needs when undertaking independent scientific research.

Equine Stress: Neuroendocrine Physiology and Pathophysiology (2022)
Book Chapter

Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial (2022)
Journal Article

Claw horn lesions (CHL) are reported as the most common cause of lameness in intensive dairy systems. Despite their prevalence, the underlying pathological mechanisms and preventive strategies for CHL remain poorly understood. Recent advances have po... Read More about Effects of routine treatment with nonsteroidal anti-inflammatory drugs at calving and when lame on the future probability of lameness and culling in dairy cows: A randomized controlled trial.

Genetic Therapy in Veterinary Medicine (2022)
Journal Article

Gene therapy focuses on the genetic modification of cells, to produce a therapeutic effect or for the treatment of disease, by repairing or reconstructing defective genetic material. The development of genetic engineering and biotechnology makes it p... Read More about Genetic Therapy in Veterinary Medicine.

Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases (2022)
Book Chapter

Mesenchymal stem cells (MSC) are specific cell types that enable tissue renewal within the body and are activated during the regeneration processes in response to injury. These cells are present in all human and animal tissues. In medical and biologi... Read More about Preclinical Research of Mesenchymal Stem Cell-Based Therapy for Ocular Diseases.

Viral Vector Vaccines Against ASF: Problems and Prospectives (2022)
Journal Article

African swine fever (ASF) is a highly contagious viral disease affecting pigs, with mortality rates a primary focus as they can reach up to 100%. The widespread and colossal economic losses from ASF have impacts on the development of animal husbandry... Read More about Viral Vector Vaccines Against ASF: Problems and Prospectives.

Health care providers’ awareness on medical management of children with autism spectrum disorder: cross-sectional study in Russia (2022)
Journal Article

Background: Autism spectrum disorder (ASD) is a complex developmental range of conditions that involves difficulties with social interaction and restricted/repetitive behaviors. Unfortunately, health care providers often experience difficulties in di... Read More about Health care providers’ awareness on medical management of children with autism spectrum disorder: cross-sectional study in Russia.

Discovery Of A Bone In Chimpanzee Hearts (2022)
Journal Article

The os cordis (heart bone) is a rare bone found only in a few animals in the world. We discovered an os cordis in some chimpanzees. The os cordis was found in males and females, and in young and old animals. It was not present in chimps with healthy... Read More about Discovery Of A Bone In Chimpanzee Hearts.

Why Do We Need Maths in Medicine? (2021)
Journal Article

Maths is a crucial part of medicine. All the graphs, equations, statistics, and general maths we learn at school help us to understand important aspects of human and veterinary medicine, biology, and science in general. People always think that biolo... Read More about Why Do We Need Maths in Medicine?.

Comparative pathology of dog and human prostate cancer (2021)
Journal Article

Though relatively rare in dogs, prostate cancer (PCa) is the most common non-cutaneous cancer in men. Human and canine prostate glands share many functional, anatomical and physiological features. Due to these similarities, canine PCa has been propos... Read More about Comparative pathology of dog and human prostate cancer.

Recent Advances in Experimental Dendritic Cell Vaccines for Cancer (2021)
Journal Article

The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies. There was no breakthrough after first using of personalized therapeutic vaccines based on... Read More about Recent Advances in Experimental Dendritic Cell Vaccines for Cancer.

Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection (2021)
Journal Article

The canine epigastric organs, their locations and visualization of these components are essential for veterinary practice and anatomical research. Despite their importance, conflicts and discrepancies in the published material, to date, still exist,... Read More about Morphological investigation of canine epigastric organs and adjacent structures via computed tomography, ultrasound and anatomical prosection.

Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma (2021)
Journal Article

Osteosarcoma (OSA) is an aggressive bone malignancy. Unlike many other malignancies, OSA outcomes have not improved in recent decades. One challenge to the development of better diagnostic and therapeutic methods for OSA has been the lack of well cha... Read More about Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma.

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