The effect of pulmonary rehabilitation on mortality, balance, and risk of fall in stable patients with chronic obstructive pulmonary disease: a systematic review
Hakamy, Ali; Bolton, Charlotte E.; McKeever, Tricia M.
CHARLOTTE BOLTON email@example.com
Professor of Respiratory Medicine
TRICIA MCKEEVER firstname.lastname@example.org
Professor of Epidemiology and Medical Statistics
Objectives: To evaluate the impact of pulmonary rehabilitation on survival and fall (including balance) in patients with chronic obstructive pulmonary disease (COPD) at stability.
Design: Systematic Review.
Methods: OVID, MEDLINE, EMBASE, and Cochrane Collaboration Library were searched for literature dating from January 1980 up to November 2014 as well as an update in October 2015. Two reviewers screened titles, abstracts and full text records, extracted data and assessed studies for risk of bias; any disagreements were resolved by a third member of the team, and consensus was always sought.
Results: Initial searches yielded 3216 records but after review, only 7 studies were included and no studies focused solely on falls. Two cohort studies found some positive benefits of pulmonary rehabilitation on balance but the results were inconsistent across the studies. Regarding survival, two randomised controlled trials were conducted; one study showed significant survival benefit at 1 year while the other one showed non-significant survival benefit at 3 years. Neither were adequately powered and in both, survival was a secondary outcome.
Conclusions: There was only limited inconclusive evidence to show that pulmonary rehabilitation has a significant beneficial effect on balance or survival.
Hakamy, A., Bolton, C. E., & McKeever, T. M. (2017). The effect of pulmonary rehabilitation on mortality, balance, and risk of fall in stable patients with chronic obstructive pulmonary disease: a systematic review. Chronic Respiratory Disease, 14(1), https://doi.org/10.1177/1479972316661925
|Journal Article Type||Article|
|Acceptance Date||May 11, 2016|
|Online Publication Date||Aug 20, 2016|
|Publication Date||Feb 1, 2017|
|Deposit Date||Aug 3, 2016|
|Publicly Available Date||Aug 20, 2016|
|Journal||Chronic Respiratory Disease|
|Peer Reviewed||Peer Reviewed|
|Keywords||COPD, Pulmonary Rehabilitation, Survival, Mortality, Fall, Balance|
|Copyright Statement||Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf|
Systematic Review Revised manuscript (unmarked).pdf
Copyright information regarding this work can be found at the following address: http://eprints.nottingham.ac.uk/end_user_agreement.pdf
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