Omer Elneima
Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study
Elneima, Omer; McAuley, Hamish J C; Leavy, Olivia C; Chalmers, James D; Horsley, Alex; Ho, Ling-Pei; Marks, Michael; Poinasamy, Krisnah; Raman, Betty; Shikotra, Aarti; Singapuri, Amisha; Sereno, Marco; Harris, Victoria C; Houchen-Wolloff, Linzy; Saunders, Ruth M; Greening, Neil J; Richardson, Matthew; Quint, Jennifer K; Briggs, Andrew; Docherty, Annemarie B; Kerr, Steven; Harrison, Ewen M; Lone, Nazir I; Thorpe, Mathew; Heaney, Liam G; Lewis, Keir E; Aul, Raminder; Beirne, Paul; Bolton, Charlotte E; Brown, Jeremy S; Choudhury, Gourab; Diar Bakerly, Nawar; Easom, Nicholas; Echevarria, Carlos; Fuld, Jonathan; Hart, Nick; Hurst, John R; Jones, Mark G; Parekh, Dhruv; Pfeffer, Paul; Rahman, Najib M; Rowland-Jones, Sarah L; Roger Thompson, Aa; Jolley, Caroline; Shah, Ajay M; Wootton, Dan G; Chalder, Trudie; Davies, Melanie J; De Soyza, Anthony; Geddes, John R; Greenhalf, William; Heller, Simon; Howard, Luke S; Jacob, Joseph; Gisli Jenkins, R; Lord, Janet M; D-C Man, William; McCann, Gerry P;...
Authors
Hamish J C McAuley
Olivia C Leavy
James D Chalmers
Alex Horsley
Ling-Pei Ho
Michael Marks
Krisnah Poinasamy
Betty Raman
Aarti Shikotra
Amisha Singapuri
Marco Sereno
Victoria C Harris
Linzy Houchen-Wolloff
Ruth M Saunders
Neil J Greening
Matthew Richardson
Jennifer K Quint
Andrew Briggs
Annemarie B Docherty
Steven Kerr
Ewen M Harrison
Nazir I Lone
Mathew Thorpe
Liam G Heaney
Keir E Lewis
Raminder Aul
Paul Beirne
Professor CHARLOTTE BOLTON charlotte.bolton@nottingham.ac.uk
Professor of Respiratory Medicine
Jeremy S Brown
Gourab Choudhury
Nawar Diar Bakerly
Nicholas Easom
Carlos Echevarria
Jonathan Fuld
Nick Hart
John R Hurst
Mark G Jones
Dhruv Parekh
Paul Pfeffer
Najib M Rahman
Sarah L Rowland-Jones
Aa Roger Thompson
Caroline Jolley
Ajay M Shah
Dan G Wootton
Trudie Chalder
Melanie J Davies
Anthony De Soyza
John R Geddes
William Greenhalf
Simon Heller
Luke S Howard
Joseph Jacob
R Gisli Jenkins
Janet M Lord
William D-C Man
Gerry P McCann
Stefan Neubauer
Peter Jm Openshaw
Joanna C Porter
Matthew J Rowland
Janet T Scott
Malcolm G Semple
Sally J Singh
David C Thomas
Mark Toshner
Nikki Smith
Aziz Sheikh
Christopher E Brightling
Louise V Wain
Rachael A Evans
on Behalf of the PHOSP-COVID Collaborative Group
Abstract
The Post-Hospitalisation COVID-19 (PHOSP-COVID) study is a national UK multicentre cohort study of patients who were hospitalized for COVID-19 and subsequently discharged.
PHOSP-COVID was established to investigate the medium- and long-term sequelae of severe COVID-19 requiring hospitalization, understand the underlying mechanisms of these sequelae, evaluate the medium- and long-term effects of COVID-19 treatments and to serve as a platform to enable future studies, including clinical trials.
Data collected covered a wide range of physical measures, biological samples and patient-reported outcome measures (PROMs).
Participants could join the cohort either in Tier 1 only with remote data collection using hospital records, a PROMs app and postal saliva sample for DNA; or in Tier 2 in which they were invited to attend two specific research visits for further data collection and biological research sampling. These research visits occurred at 5 (range 2–7) months and 12 (range 10–14) months post-discharge. Participants could also participate in specific nested studies (Tier 3) at selected sites.
All participants were asked to consent to further follow-up for 25 years via linkage to their electronic healthcare records and to be re-contacted for further research.
In total, 7935 participants were recruited from 83 UK sites: 5238 to Tier 1 and 2697 to Tier 2, between August 2020 and March 2022.
Cohort data are held in a Trusted Research Environment and samples stored in a central biobank. Data and samples can be accessed upon request and subject to approvals from https://www.phosp.org/data-sample-request/.
Citation
Elneima, O., McAuley, H. J. C., Leavy, O. C., Chalmers, J. D., Horsley, A., Ho, L.-P., Marks, M., Poinasamy, K., Raman, B., Shikotra, A., Singapuri, A., Sereno, M., Harris, V. C., Houchen-Wolloff, L., Saunders, R. M., Greening, N. J., Richardson, M., Quint, J. K., Briggs, A., Docherty, A. B., …Behalf of the PHOSP-COVID Collaborative Group, O. (2024). Cohort Profile: Post-Hospitalisation COVID-19 (PHOSP-COVID) study. International Journal of Epidemiology, 53(1), Article dyad165. https://doi.org/10.1093/ije/dyad165
Journal Article Type | Article |
---|---|
Acceptance Date | Dec 7, 2023 |
Online Publication Date | Dec 18, 2023 |
Publication Date | Feb 1, 2024 |
Deposit Date | Feb 29, 2024 |
Publicly Available Date | Feb 29, 2024 |
Journal | International Journal of Epidemiology |
Print ISSN | 0300-5771 |
Electronic ISSN | 1464-3685 |
Publisher | Oxford University Press |
Peer Reviewed | Peer Reviewed |
Volume | 53 |
Issue | 1 |
Article Number | dyad165 |
DOI | https://doi.org/10.1093/ije/dyad165 |
Keywords | General Medicine, Epidemiology |
Public URL | https://nottingham-repository.worktribe.com/output/29257648 |
Publisher URL | https://academic.oup.com/ije/article/53/1/dyad165/7477903 |
Files
dyad165
(1.1 Mb)
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Publisher Licence URL
https://creativecommons.org/licenses/by/4.0/
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