Outputs (37)

Outcomes of non-anaplastic stage III and ‘inoperable’ Wilms tumour treated in the UKW3 trial (2018)
Journal Article

© 2018 Background and purpose: To describe the outcome of patients with stage III Wilms tumours (WT) treated in the UKW3 trial. Material and methods: Patients with a pathologically confirmed stage III non-anaplastic WT at nephrectomy (Group A) or wit... Read More about Outcomes of non-anaplastic stage III and ‘inoperable’ Wilms tumour treated in the UKW3 trial.

Brown adipose tissue and glucose homeostasis – the link between climate change and the global rise in obesity and diabetes (2018)
Journal Article

There is increasing evidence that the global rise in temperature is contributing to the onset of diabetes, which could be mediated by a concomitant reduction in brown fat activity. Brown (and beige) fat are characterised as possessing a unique mitoch... Read More about Brown adipose tissue and glucose homeostasis – the link between climate change and the global rise in obesity and diabetes.

Enteral lactoferrin to prevent infection for very preterm infants: the ELFIN RCT (2018)
Journal Article

Postnatal gestational age estimation of newborns using Small Sample Deep Learning (2018)
Journal Article

© 2018 A baby's gestational age determines whether or not they are premature, which helps clinicians decide on suitable post-natal treatment. The most accurate dating methods use Ultrasound Scan (USS) machines, but these are expensive, require traine... Read More about Postnatal gestational age estimation of newborns using Small Sample Deep Learning.

Restricted visiting reduces nosocomial viral respiratory tract infections in high-risk neonates (2018)
Journal Article

Restricting visitors on the neonatal intensive care unit to parents only during a worldwide pandemic resulted in a 39% reduction in nosocomial viral respiratory tract infections in neonatal patients. These findings need validating in a prospective tr... Read More about Restricted visiting reduces nosocomial viral respiratory tract infections in high-risk neonates.

The Impact of Maternal Pre-Pregnancy Body Weight and Gestational Diabetes on Markers of Folate Metabolism in the Placenta (2018)
Journal Article

Dietary methyl donors, including folate, may modify the placenta and size at birth but the influence of maternal body weight has not been widely investigated. We therefore examined whether maternal or fetal folate status, together with indices of pla... Read More about The Impact of Maternal Pre-Pregnancy Body Weight and Gestational Diabetes on Markers of Folate Metabolism in the Placenta.

Negative correlation between Placental Growth Factor and Endocan-1 in women with preeclampsia (2018)
Journal Article

Objective: To analyse Endocan-1, a biomarker of vascular endothelial related pathologies, and Placental growth factor (PlGF), an angiogenic factor and a placental dysfunction marker in patients with pre-eclampsia (PE). Methods: Case-control study c... Read More about Negative correlation between Placental Growth Factor and Endocan-1 in women with preeclampsia.

The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data (2018)
Journal Article

Background: We aimed to establish a national cystic fibrosis (CF) registry for Cuba, a developing country. Methods: Regional centres that deliver care for all CF patients provided information for a national database. Findings: The prevalence of CF... Read More about The prevalence, clinical status and genotype of cystic fibrosis patients living in Cuba using national registry data.

Epilepsy and associated mortality in patients with multiple sclerosis (2018)
Journal Article

Background and purpose: We aimed to determine the prevalence of epilepsy in patients with multiple sclerosis (MS) at diagnosis, the risk of developing epilepsy after the diagnosis of MS and the relative risk of mortality associated with epilepsy. Me... Read More about Epilepsy and associated mortality in patients with multiple sclerosis.

Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review (2018)
Journal Article

Introduction:Cystic fibrosis (CF) is a multisystem disorder. Treatment is complex and evidence for treatment decisions may be absent. Characterising gaps in the research evidence will highlight treatment uncertainties and help prioritise research que... Read More about Gaps in the evidence for treatment decisions in cystic fibrosis: a systematic review.