Outputs (167)

Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis (2023)
Journal Article
Dunn, E., Steinert, J. R., Stone, A., Sahota, V., Williams, R. S. B., Snowden, S., & Augustin, H. (2023). Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis. Cells, 12(17), Article 2163. https://doi.org/10.3390/cells12172163

Amyotrophic lateral sclerosis (ALS) is an adult-onset neurodegenerative disease characterised by progressive degeneration of the motor neurones. An expanded GGGGCC (G4C2) hexanucleotide repeat in C9orf72 is the most common genetic cause of ALS and fr... Read More about Medium-Chain Fatty Acids Rescue Motor Function and Neuromuscular Junction Degeneration in a Drosophila Model of Amyotrophic Lateral Sclerosis.

In vivo observation of a stomach road or ‘Magenstrasse’ for gastric emptying using MRI imaging in healthy humans (2023)
Journal Article
Almutairi, F., Alyami, J., Pritchard, S., Alsharef, W., Spiller, R. C., Gowland, P. A., …Hoad, C. L. (2023). In vivo observation of a stomach road or ‘Magenstrasse’ for gastric emptying using MRI imaging in healthy humans. Clinical Nutrition Open Science, 51, 35-43. https://doi.org/10.1016/j.nutos.2023.08.002

The presence of a ‘magenstrasse’, a central ‘stomach road’ for flow and mixing of foods and drinks in the stomach had been predicted from hydrodynamic modelling. Here a magnetic resonance imaging (MRI) tagging technique was used to gain novel insight... Read More about In vivo observation of a stomach road or ‘Magenstrasse’ for gastric emptying using MRI imaging in healthy humans.

Systematic Review: Sarcopenia in paediatric inflammatory bowel disease (2023)
Journal Article
Aljilani, B., Tsintzas, K., Jacques, M., Radford, S., & Moran, G. W. (2023). Systematic Review: Sarcopenia in paediatric inflammatory bowel disease. Clinical Nutrition ESPEN, 57, 647-654. https://doi.org/10.1016/j.clnesp.2023.08.009

Background: Low skeletal muscle mass (MM) and deteriorated function (sarcopenia) can be a frequent complication in paediatric inflammatory bowel disease (IBD). Aim: To conduct a systematic review of the paediatric IBD literature on skeletal muscle fu... Read More about Systematic Review: Sarcopenia in paediatric inflammatory bowel disease.

Molecular phylogeny and morphological evolution of the Chinese land snail Cathaica Möllendorff, 1884 (Eupulmonata: Camaenidae) in Shandong Province, China (2023)
Journal Article
Zhang, G., & Wade, C. M. (2023). Molecular phylogeny and morphological evolution of the Chinese land snail Cathaica Möllendorff, 1884 (Eupulmonata: Camaenidae) in Shandong Province, China. Biological Journal of the Linnean Society, 140(4), 556-577. https://doi.org/10.1093/biolinnean/blad067

Cathaica is a genus of bradybaenid land snails occurring in China and is widespread in Shandong Province. Here we re-describe three species, C. pyrrhozona, C. fasciola and C. leei, and describe two new species, Cathaica fohuiensis Zhang sp. nov. and... Read More about Molecular phylogeny and morphological evolution of the Chinese land snail Cathaica Möllendorff, 1884 (Eupulmonata: Camaenidae) in Shandong Province, China.

A potential alternative to fungicides using actives-free (meth)acrylate polymers for protection of wheat crops from fungal attachment and infection (2023)
Journal Article
Crawford, L. A., Cuzzucoli Crucitti, V., Stimpson, A., Morgan, C., Blake, J., Wildman, R. D., …Avery, S. V. (2023). A potential alternative to fungicides using actives-free (meth)acrylate polymers for protection of wheat crops from fungal attachment and infection. Green Chemistry, 25(21), 8558-8569. https://doi.org/10.1039/d3gc01911j

Fungicidal compounds are actives widely used for crop protection from fungal infection, but they can also kill beneficial organisms, enter the food chain and promote resistant pathogen strains from overuse. Here we report the first field crop trial o... Read More about A potential alternative to fungicides using actives-free (meth)acrylate polymers for protection of wheat crops from fungal attachment and infection.

Seasonal patterns of Schistosoma mansoni infection within Biomphalaria snails at the Ugandan shorelines of Lake Albert and Lake Victoria (2023)
Journal Article
Andrus, P. S., Stothard, J. R., & Wade, C. M. (2023). Seasonal patterns of Schistosoma mansoni infection within Biomphalaria snails at the Ugandan shorelines of Lake Albert and Lake Victoria. PLoS Neglected Tropical Diseases, 17(8), Article e0011506. https://doi.org/10.1371/journal.pntd.0011506

Intestinal schistosomiasis is hyperendemic in many sub-Saharan African countries. In Uganda, it is endemic at both Lake Albert (LA) and Lake Victoria (LV) and caused by S. mansoni that uses Biomphalaria snails as obligatory intermediate snail hosts.... Read More about Seasonal patterns of Schistosoma mansoni infection within Biomphalaria snails at the Ugandan shorelines of Lake Albert and Lake Victoria.

Quorum-sensing, intra- and inter-species competition in the staphylococci (2023)
Journal Article
Williams, P., Hill, P., Bonev, B., & Chan, W. C. (2023). Quorum-sensing, intra- and inter-species competition in the staphylococci. Microbiology, 169(8), https://doi.org/10.1099/mic.0.001381

In Gram-positive bacteria such as Staphylococcus aureus and the coagulase-negative staphylococci (CoNS), the accessory gene regulator (agr) is a highly conserved but polymorphic quorum-sensing system involved in colonization, virulence and biofilm de... Read More about Quorum-sensing, intra- and inter-species competition in the staphylococci.

Emergent mechanical control of vascular morphogenesis (2023)
Journal Article
Whisler, J., Shahreza, S., Schlegelmilch, K., Ege, N., Javanmardi, Y., Malandrino, A., …Moeendarbary, E. (2023). Emergent mechanical control of vascular morphogenesis. Science Advances, 9(32), Article eadg9781. https://doi.org/10.1126/sciadv.adg9781

Vascularization is driven by morphogen signals and mechanical cues that coordinately regulate cellular force generation, migration, and shape change to sculpt the developing vascular network. However, it remains unclear whether developing vasculature... Read More about Emergent mechanical control of vascular morphogenesis.

Combined genomics to discover genes associated with tolerance to soil carbonate (2023)
Journal Article
Busoms, S., Pérez‐Martín, L., Terés, J., Huang, X., Yant, L., Tolrà, R., …Poschenrieder, C. (2023). Combined genomics to discover genes associated with tolerance to soil carbonate. Plant, Cell and Environment, 46(12), 3986-3998. https://doi.org/10.1111/pce.14691

Carbonate‐rich soils limit plant performance and crop production. Previously, local adaptation to carbonated soils was detected in wild Arabidopsis thaliana accessions, allowing the selection of two demes with contrasting phenotypes: A1 (carbonate to... Read More about Combined genomics to discover genes associated with tolerance to soil carbonate.

Preservation of whole antibodies within ancient teeth (2023)
Journal Article
Shaw, B., McDonnell, T., Radley, E., Thomas, B., Smith, L., Davenport, C. A. L., …Layfield, R. (2023). Preservation of whole antibodies within ancient teeth. iScience, 26(9), Article 107575. https://doi.org/10.1016/j.isci.2023.107575

Archaeological remains can preserve some proteins into deep time, offering remarkable opportunities for probing past events in human history. Recovering functional proteins from skeletal tissues could uncover a molecular memory related to the life-hi... Read More about Preservation of whole antibodies within ancient teeth.