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JO LEONARDI-BEE's Outputs (92)

The Use of Virtual Patients to Provide Feedback On Clinical Reasoning : A Systematic Review (2024)
Journal Article
Jay, R., Sandars, J., Patel, R., Leonardi-Bee, J., Ackbarally, Y., Bandyopadhyaya, S., Faraj, D., O'Hanlon, M., Brown, J., & Wilson, E. (2024). The Use of Virtual Patients to Provide Feedback On Clinical Reasoning : A Systematic Review. Academic Medicine,

Purpose: Virtual patients (VPs) are increasingly used across the continuum of medical education to support the development of clinical reasoning (CR). However, the extent to which feedback is given across the components of CR is unknown, and there is... Read More about The Use of Virtual Patients to Provide Feedback On Clinical Reasoning : A Systematic Review.

Sexual and reproductive health needs of women with severe mental illness in low- and middle-income countries: A scoping review (2024)
Journal Article
Sisodia, S., Hammond, Z., Leonardi-Bee, J., Hanlon, C., & Asher, L. (in press). Sexual and reproductive health needs of women with severe mental illness in low- and middle-income countries: A scoping review. PLoS ONE,

Background

This scoping review aimed to understand the extent and type of evidence in relation to sexual and reproductive health needs of women with severe mental illness (SMI) in low- and middle-income countries (LMIC) and to summarise those nee... Read More about Sexual and reproductive health needs of women with severe mental illness in low- and middle-income countries: A scoping review.

Digitalising Specialist Smoking Cessation Support in Pregnancy: Views of Pregnant Smokers (2024)
Journal Article
Belderson, P., McDaid, L., Emery, J., Coleman, T., Leonardi-Bee, J., & Naughton, F. (2024). Digitalising Specialist Smoking Cessation Support in Pregnancy: Views of Pregnant Smokers. Nicotine and Tobacco Research, Article ntae184. https://doi.org/10.1093/ntr/ntae184

Introduction

Unsupported attempts to quit smoking during pregnancy have a low success rate. Chances of quitting successfully are higher with an interpersonal treatment programme but there is low uptake of this in the United Kingdom (UK). Deliverin... Read More about Digitalising Specialist Smoking Cessation Support in Pregnancy: Views of Pregnant Smokers.

A rapid literature review of the effect of alcohol marketing on people with, or at increased risk of, an alcohol problem. (2024)
Journal Article
Murray, R. L., Leonardi-Bee, J., Barker, A., Brown, O., & Langley, T. (2024). A rapid literature review of the effect of alcohol marketing on people with, or at increased risk of, an alcohol problem. Alcohol and Alcoholism, 59(4), Article agae045. https://doi.org/10.1093/alcalc/agae045

To explore the effect or potential effect of alcohol marketing in people with an alcohol use disorder, in recovery from an alcohol use disorder, and hazardous and harmful drinkers. Relevant literature was identified by searching Medline (OVID), EMBAS... Read More about A rapid literature review of the effect of alcohol marketing on people with, or at increased risk of, an alcohol problem..

Health net-outcome objectives and approaches for spatial planning and development: a scoping review protocol (2024)
Journal Article
Stewart-Evans, J., Wilson, E., Langley, T., Hands, A., & Leonardi-Bee, J. (2024). Health net-outcome objectives and approaches for spatial planning and development: a scoping review protocol. JBI Evidence Synthesis, 22(11), 2394-2403. https://doi.org/10.11124/JBIES-23-00464

Objective: The objective of this scoping review is to review the body of knowledge on net gain and no net loss (net-outcome) objectives and approaches applicable to health in spatial planning and development policies and practice. Introduction: There... Read More about Health net-outcome objectives and approaches for spatial planning and development: a scoping review protocol.

Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review (2024)
Journal Article
Kontou, E., Shokraneh, F., das Nair, R., Quinn, T., Leonardi-Bee, J., Thorpe, N., …Drummond, A. (2024). Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review. F1000Research, 13, 1-15. https://doi.org/10.12688/f1000research.146343.2

Background People who have had a stroke or a Transient Ischaemic Attack (TIA) can experience psychological and/or cognitive difficulties. The body of research for psychological and neuropsychological interventions after stroke is growing, however, pu... Read More about Psychological interventions for mood and cognition after stroke and transient ischaemic attack: A protocol for an umbrella review.

What are the strengths and limitations to utilising creative methods in public and patient involvement in health and social care research? A qualitative systematic review (2024)
Journal Article
Phillips, O. R., Harries, C., Leonardi-Bee, J., Knight, H., Sherar, L. B., Varela-Mato, V., & Morling, J. R. (2024). What are the strengths and limitations to utilising creative methods in public and patient involvement in health and social care research? A qualitative systematic review. Research Involvement and Engagement, 10(1), Article 48. https://doi.org/10.1186/s40900-024-00580-4

Background: There is increasing interest in using patient and public involvement (PPI) in research to improve the quality of healthcare. Ordinarily, traditional methods have been used such as interviews or focus groups. However, these methods tend to... Read More about What are the strengths and limitations to utilising creative methods in public and patient involvement in health and social care research? A qualitative systematic review.

Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study (2024)
Journal Article
Sahota, O., Narayanasamy, M., Bastounis, A., Paskins, Z., Bishop, S., Langley, T., …Leonardi-Bee, J. (2024). Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study. Health Technology Assessment, 28(21), https://doi.org/10.3310/WYPF0472

Background: Bisphosphonates are a class of medication commonly used to treat osteoporosis. Alendronate is recommended as the first-line treatment; however, long-term adherence (both treatment compliance and persistence) is poor. Alternative bisphosph... Read More about Bisphosphonate alternative regimens for the prevention of osteoporotic fragility fractures: BLAST-OFF, a mixed-methods study.

The impact of conflict on infectious disease: a systematic literature review (2024)
Journal Article
Marou, V., Vardavas, C. I., Aslanoglou, K., Nikitara, K., Plyta, Z., Leonardi-Bee, J., …Suk, J. E. (2024). The impact of conflict on infectious disease: a systematic literature review. Conflict and Health, 18(1), Article 27. https://doi.org/10.1186/s13031-023-00568-z

Background: Conflict situations, armed or not, have been associated with emergence and transmission of infectious diseases. This review aims to identify the pathways through which infectious diseases emerge within conflict situations and to outline a... Read More about The impact of conflict on infectious disease: a systematic literature review.

Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention (2024)
Journal Article
McDaid, L., Belderson, P., Emery, J., Coleman, T., Leonardi-Bee, J., & Naughton, F. (2024). Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention. PLOS Digital Health, 3(3), Article e0000472. https://doi.org/10.1371/journal.pdig.0000472

Many pregnant smokers need support to quit successfully. In the United Kingdom, trained smoking cessation advisors deliver structured behavioural counselling alongside access to free nicotine replacement therapy (NRT); known as the ‘Standard Treatmen... Read More about Experts’ views on translating NHS support to stop smoking in pregnancy into a comprehensive digital intervention.

The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action (2024)
Journal Article
Emery, J., Leonardi-Bee, J., Coleman, T., McDaid, L., & Naughton, F. (2024). The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action. Nicotine & Tobacco Research, 26(8), 1072-1080. https://doi.org/10.1093/ntr/ntae026

Introduction
Digital cessation support appeals to pregnant smokers. In two pooled RCTs, MiQuit, a pregnancy-specific tailored text messaging intervention, did not show effectiveness for validated prolonged abstinence. However, secondary outcomes and... Read More about The effectiveness of text support for stopping smoking in pregnancy (MiQuit): multi-trial pooled analysis investigating effect moderators and mechanisms of action.

Age and sex differences in LDL cholesterol distribution in adults in Malaysia: A cross-sectional study (2010 -2021) (2023)
Journal Article
Chalitsios, C. V., Akyea, R. K., Abdul-Hamid, H., Leonardi-Bee, J., Kanchau, J. D., Kamal, A., …Qureshi, N. (2023). Age and sex differences in LDL cholesterol distribution in adults in Malaysia: A cross-sectional study (2010 -2021). International Journal of General Medicine, 2023(16), 5885—5888. https://doi.org/10.2147/IJGM.S423091

Cardiovascular disease (CVD) is the leading cause of death worldwide. Hypercholesterolaemia, especially higher low-density lipoprotein cholesterol (LDL-c), has been recognised as one of the major key risk factors for CVD. Lipid lowering treatments, s... Read More about Age and sex differences in LDL cholesterol distribution in adults in Malaysia: A cross-sectional study (2010 -2021).

Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis (2023)
Journal Article
Qureshi, N., Woods, B., Neves de Faria, R., Saramago Goncalves, P., Cox, E., Leonardi Bee, J., …Kai, J. (2023). Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis. Health Technology Assessment, 27(16), https://doi.org/10.3310/CTMD0148

Background
Cascade testing the relatives of people with familial hypercholesterolaemia is an efficient approach to identifying familial hypercholesterolaemia. The cascade-testing protocol starts with identifying an index patient with familial hyperc... Read More about Alternative cascade-testing protocols for identifying and managing patients with familial hypercholesterolaemia: systematic reviews, qualitative study and cost-effectiveness analysis.

Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study (2023)
Journal Article
Bishop, S., Narayanasamy, M. J., Paskins, Z., Corp, N., Bastounis, A., Griffin, J., …Sahota, O. (2023). Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study. BMC Musculoskeletal Disorders, 24, Article 770. https://doi.org/10.1186/s12891-023-06865-1

Background Bisphosphonate medications, including alendronate, ibandronate and risedronate administered orally and zoledronate, administered intravenously, are commonly prescribed for the treatment of osteoporosis based on evidence that, correctly tak... Read More about Clinicians’ views of prescribing oral and intravenous bisphosphonates for osteoporosis: a qualitative study.

Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis (2023)
Journal Article
Scarpone, R., Kimkool, P., Ierodiakonou, D., Leonardi-Bee, J., Garcia-Larsen, V., Perkin, M., & Boyle, R. J. (2023). Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis. JAMA Pediatrics, https://doi.org/10.1001/jamapediatrics.2023.0142

Importance: Earlier egg and peanut introduction probably reduce risk of egg or peanut allergy, but it is uncertain whether food allergy as a whole can be prevented using earlier allergenic food introduction.

Objective: This study is a systematic r... Read More about Timing of Allergenic Food Introduction and Risk of Immunoglobulin E–Mediated Food Allergy: A Systematic Review and Meta-analysis.

The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials (2023)
Journal Article
Barker, T. H., Stone, J. C., Sears, K., Klugar, M., Tufanaru, C., Leonardi-Bee, J., …Munn, Z. (2023). The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials. JBI Evidence Synthesis, 21(3), 494-506. https://doi.org/10.11124/JBIES-22-00430

JBI recently began the process of updating and revising its suite of critical appraisal tools to ensure that these tools remain compatible with recent developments within risk of bias science. Following a rigorous development process led by the JBI E... Read More about The revised JBI critical appraisal tool for the assessment of risk of bias for randomized controlled trials.

Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners (2023)
Journal Article
Chattopadhyay, K., Kapoor, N., Heinrich, M., Mitra, A., Mittal, M., Lewis, S. A., …Leonardi-Bee, J. (2023). Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners. Frontiers in Medicine, 10, Article 1043715. https://doi.org/10.3389/fmed.2023.1043715

Background: Type 2 diabetes mellitus (T2DM), a common chronic health condition, has major health and socioeconomic consequences. In the Indian subcontinent, it is a health condition for which individuals commonly consult Ayurvedic (traditional medica... Read More about Development process of a clinical guideline to manage type 2 diabetes in adults by Ayurvedic practitioners.

Content and quality of clinical practice guidelines for the management of type 2 diabetes in India: A systematic review (2023)
Journal Article
Olujide, O. P., Olujide, M. E., Leonardi-Bee, J., & Chattopadhyay, K. (2023). Content and quality of clinical practice guidelines for the management of type 2 diabetes in India: A systematic review. Endocrinology, Diabetes and Metabolism, 6(2), Article e405. https://doi.org/10.1002/edm2.405

Introduction: Over the last few decades, India has witnessed an increase in the number of people with type 2 diabetes mellitus (T2DM). Consequently, several clinical practice guidelines (CPGs) have been developed to assist western and traditional Ind... Read More about Content and quality of clinical practice guidelines for the management of type 2 diabetes in India: A systematic review.

Systematic review of outbreaks of COVID-19 within households in the European region when the child is the index case (2023)
Journal Article
Vardavas, C. I., Nikitara, K., Aslanoglou, K., Kamekis, A., Ramesh, N., Symvoulakis, E., …Suk, J. E. (2023). Systematic review of outbreaks of COVID-19 within households in the European region when the child is the index case. BMJ Paediatrics Open, 7(1), Article e001718. https://doi.org/10.1136/bmjpo-2022-001718

Objectives This systematic review aims to identify the secondary attack rates (SAR) to adults and other children when children are the index cases within household settings.

Methods This literature review assessed European-based studies published... Read More about Systematic review of outbreaks of COVID-19 within households in the European region when the child is the index case.

Assessing the risk of bias of quantitative analytical studies: introducing the vision for critical appraisal within JBI systematic reviews (2022)
Journal Article
Munn, Z., Stone, J., Aromataris, E., Klugar, M., Sears, K., Leonardi-Bee, J., & Barker, T. H. (2023). Assessing the risk of bias of quantitative analytical studies: introducing the vision for critical appraisal within JBI systematic reviews. JBI Evidence Synthesis, 21(3), 467-471. https://doi.org/10.11124/JBIES-22-00224

A key step in the systematic review process is the assessment of the methodological quality (or risk of bias) of the included studies. At JBI, we have developed several tools to assist with this evaluation. As evidence synthesis methods continue to e... Read More about Assessing the risk of bias of quantitative analytical studies: introducing the vision for critical appraisal within JBI systematic reviews.

A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol (2022)
Journal Article
Chattopadhyay, K., Dhimal, M., Karki, S., Regmi, P., Bista, B., Biswas, T. K., …Gyanwali, P. (2022). A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol. Medicine, 101(47), Article e31452. https://doi.org/10.1097/MD.0000000000031452

Introduction:
Type 2 diabetes mellitus (T2DM) is a common chronic condition with significant health and socioeconomic consequences. In Nepal, T2DM is a common disease for which people consult ayurvedic (traditional medical system) practitioners and... Read More about A clinical guideline-based management of type 2 diabetes by ayurvedic practitioners in Nepal: A feasibility cluster randomized controlled trial protocol.

Mosquito aquatic habitat modification and manipulation interventions to control malaria (2022)
Journal Article
Martello, E., Yogeswaran, G., Reithinger, R., & Leonardi-Bee, J. (2022). Mosquito aquatic habitat modification and manipulation interventions to control malaria. Cochrane Database of Systematic Reviews, 2022(11), Article CD008923. https://doi.org/10.1002/14651858.CD008923.pub3

Background: Larval source management (LSM) may help reduce Plasmodium parasite transmission in malaria-endemic areas. LSM approaches include habitat modification (permanently or temporarily reducing mosquito breeding aquatic habitats); habitat manipu... Read More about Mosquito aquatic habitat modification and manipulation interventions to control malaria.

Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe (2022)
Journal Article
Vardavas, C. I., Mathioudakis, A. G., Nikitara, K., Stamatelopoulos, K., Georgiopoulos, G., Phalkey, R., …Penttinen, P. (2022). Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe. European Respiratory Review, 31(166), Article 220098. https://doi.org/10.1183/16000617.0098-2022

Background As mortality from coronavirus disease 2019 (COVID-19) is strongly age-dependent, we aimed to identify population subgroups at an elevated risk for adverse outcomes from COVID-19 using age-/gender-adjusted data from European cohort studies... Read More about Prognostic factors for mortality, intensive care unit and hospital admission due to SARS-CoV-2: a systematic review and meta-analysis of cohort studies in Europe.

Systematic review on the non-vectorial transmission of Tick-borne encephalitis virus (TBEv) (2022)
Journal Article
Martello, E., Gillingham, E. L., Phalkey, R., Vardavas, C., Nikitara, K., Bakonyi, T., …Leonardi-Bee, J. (2022). Systematic review on the non-vectorial transmission of Tick-borne encephalitis virus (TBEv). Ticks and Tick-borne Diseases, 13(6), Article 102028. https://doi.org/10.1016/j.ttbdis.2022.102028

Tick-borne encephalitis (TBE) is an infection caused by the Tick-borne encephalitis virus (TBEv) and it is common in Europe. The virus is predominantly transmitted by ticks, but other non-vectorial modes of transmission are possible. This systematic... Read More about Systematic review on the non-vectorial transmission of Tick-borne encephalitis virus (TBEv).

Association of built environment constructs and physical activity among children and adolescents in Africa: a systematic review and meta-analysis (2022)
Journal Article
Adebusoye, B., Chattopadhyay, K., Ekezie, W., Phalkey, R., & Leonardi-Bee, J. (2022). Association of built environment constructs and physical activity among children and adolescents in Africa: a systematic review and meta-analysis. JBI Evidence Synthesis, 20(10), 2410-2444. https://doi.org/10.11124/JBIES-21-00295

Objective:
The objective of this review was to synthesize the association between built environment constructs and physical activity among children and adolescents in Africa.

Introduction:
Previous reviews have found that several built environ... Read More about Association of built environment constructs and physical activity among children and adolescents in Africa: a systematic review and meta-analysis.

Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis (2022)
Journal Article
Chattopadhyay, K., Wang, H., Kaur, J., Nalbant, G., Almaqhawi, A. K., Kundakci, B., …Leonardi-Bee, J. (2022). Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis. Frontiers in Pharmacology, 13, Article 821810. https://doi.org/10.3389/fphar.2022.821810

Introduction: Many Ayurvedic medicines have the potential for managing type 2 diabetes mellitus (T2DM), with previous systematic reviews demonstrating effectiveness and safety for specific Ayurvedic medicines. However, many of the reviews need updati... Read More about Effectiveness and Safety of Ayurvedic Medicines in Type 2 Diabetes Mellitus Management: A Systematic Review and Meta-Analysis.

Impact of Smoking and Vaping in Films on Smoking and Vaping Uptake in Adolescents: Systematic Review and Meta-Analysis (2022)
Journal Article
Hassanein, Z. M., Barker, A. B., Murray, R. L., Britton, J., Agrawal, S., & Leonardi-Bee, J. (2022). Impact of Smoking and Vaping in Films on Smoking and Vaping Uptake in Adolescents: Systematic Review and Meta-Analysis. Health Education and Behavior, 49(6), 1004-1013. https://doi.org/10.1177/10901981221086944

Prevention of smoking uptake in young people is an essential public health target. We have previously reported a systematic review and meta-analysis of the effect of exposure to smoking imagery in films on the risk of smoking uptake in young people.... Read More about Impact of Smoking and Vaping in Films on Smoking and Vaping Uptake in Adolescents: Systematic Review and Meta-Analysis.

Response to ‘The role of curettage as an intervention for basal cell carcinoma’. Re. ‘Interventions for basal cell carcinoma: abridged Cochrane systematic review and GRADE assessments’: reply from the authors (2021)
Journal Article
Bath-Hextall, F. J., Thomson, J., Hogan, S., Leonardi-Bee, J., Williams, H. C., & Bath‐Hextall, F. (2022). Response to ‘The role of curettage as an intervention for basal cell carcinoma’. Re. ‘Interventions for basal cell carcinoma: abridged Cochrane systematic review and GRADE assessments’: reply from the authors. British Journal of Dermatology, 186(4), 751-752. https://doi.org/10.1111/bjd.20950

Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus (2021)
Journal Article
Nixon, A. L., Chattopadhyay, K., & Leonardi-Bee, J. (2021). Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus. International Journal of Environmental Research and Public Health, 18(24), Article 12868. https://doi.org/10.3390/ijerph182412868

Purpose: Type 2 diabetes mellitus (T2DM) is poorly managed in the Caribbean; therefore, con-ducting an assessment of the content and quality of clinical guidelines will allow guideline de-velopers to detect and address the lacking information. Hence,... Read More about Comparison of Content and Quality of Caribbean, International, and High-Income Country-Specific Clinical Guidelines for Managing Type 2 Diabetes Mellitus.

Conduct and reporting of formula milk trials: systematic review (2021)
Journal Article
Helfer, B., Leonardi-Bee, J., Mundell, A., Parr, C., Ierodiakonou, D., Garcia-Larsen, V., …Boyle, R. J. (2021). Conduct and reporting of formula milk trials: systematic review. BMJ, 375, Article n2202. https://doi.org/10.1136/bmj.n2202

Importance: Formula milk is consumed by most infants in Europe and North America and global consumption is rising. New formula products need to be tested in clinical trials, but concerns have been raised that such trials are biased and may undermine... Read More about Conduct and reporting of formula milk trials: systematic review.

Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care (2021)
Journal Article
Qureshi, N., Akyea, R. K., Dutton, B., Leonardi-Bee, J., Humphries, S. E., Weng, S., & Kai, J. (2021). Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care. Open Heart, 8(2), Article e001752. https://doi.org/10.1136/openhrt-2021-001752

Objective Familial hypercholesterolaemia (FH) is a common inherited disorder causing premature coronary heart disease (CHD) and death. We have developed the novel Familial Hypercholesterolaemia Case Ascertainment Tool (FAMCAT 1) case-finding algorith... Read More about Comparing the performance of the novel FAMCAT algorithms and established case-finding criteria for familial hypercholesterolaemia in primary care.

Strategies for screening for familial hypercholesterolaemia in primary care and other community settings (2021)
Journal Article
Qureshi, N., Da Silva, M. L. R., Abdul-Hamid, H., Weng, S. F., Kai, J., & Leonardi-Bee, J. (2021). Strategies for screening for familial hypercholesterolaemia in primary care and other community settings. Cochrane Database of Systematic Reviews, 2021(10), Article CD012985. https://doi.org/10.1002/14651858.cd012985.pub2

Background: Familial hypercholesterolaemia is a common inherited condition that is associated with premature cardiovascular disease. The increased cardiovascular morbidity and mortality, resulting from high levels of cholesterol since birth, can be p... Read More about Strategies for screening for familial hypercholesterolaemia in primary care and other community settings.

Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis (2021)
Journal Article
Leonardi-Bee, J., Boateng, C., Faria, R., Eliman, K., Young, B., & Qureshi, N. (2021). Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis. Atherosclerosis, 338, 7-14. https://doi.org/10.1016/j.atherosclerosis.2021.09.014

Background and aims: Cascade testing in relatives of index cases is the most cost-effective approach to identifying people with familial hypercholesterolemia (FH); however, it is currently unclear which strategy to contact relatives would be the most... Read More about Effectiveness of cascade testing strategies in relatives for familial hypercholesterolemia: A systematic review and meta-analysis.

Case-finding and genetic testing for familial hypercholesterolaemia in primary care (2021)
Journal Article
Qureshi, N., Akyea, R. K., Dutton, B., Leonardi-Bee, J., Humphries, S. E., Weng, S., & Kai, J. (2021). Case-finding and genetic testing for familial hypercholesterolaemia in primary care. Heart, 107(24), 1956-1961. https://doi.org/10.1136/heartjnl-2021-319742

Objective: Familial Hypercholesterolaemia (FH) is a common inherited disorder causing premature heart disease and death. We have developed novel case-finding algorithms (FAMCAT version 1 & 2) for application in primary care, to improve detection of... Read More about Case-finding and genetic testing for familial hypercholesterolaemia in primary care.

Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (2021)
Journal Article
Doleman, B., Leonardi-Bee, J., Heinink, T. P., Boyd-Carson, H., Carrick, L., Mandalia, R., …Williams, J. P. (2021). Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery. Cochrane Database of Systematic Reviews, 2021(6), Article CD012978. https://doi.org/10.1002/14651858.cd012978.pub2

Background
Postoperative pain is a common consequence of surgery and can have many negative perioperative effects. It has been suggested that the administration of analgesia before a painful stimulus may improve pain control. We defined pre‐emptive... Read More about Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery.

Understanding willingness to access and experiences of NHS Stop Smoking Services: a qualitative systematic review with meta-aggregation synthesis (2021)
Journal Article
Latif, A., Murray, R. L., Waters, C., & Leonardi-Bee, J. (2021). Understanding willingness to access and experiences of NHS Stop Smoking Services: a qualitative systematic review with meta-aggregation synthesis. Public Health, 194, 216-222. https://doi.org/10.1016/j.puhe.2021.03.003

Objectives

NHS Stop Smoking Services (NHS-SSS) have been available in the United Kingdom (UK) since 2000. The service has proven to be effective, however uptake remains below aspirations. Understanding people's willingness and reasons for accessin... Read More about Understanding willingness to access and experiences of NHS Stop Smoking Services: a qualitative systematic review with meta-aggregation synthesis.

Cost-effectiveness of emergency preparedness measures in response to infectious respiratory disease outbreaks: a systematic review and econometric analysis (2021)
Journal Article
Vardavas, C., Nikitara, K., Zisis, K., Athanasakis, K., Phalkey, R., Leonardi-Bee, J., …Suk, J. E. (2021). Cost-effectiveness of emergency preparedness measures in response to infectious respiratory disease outbreaks: a systematic review and econometric analysis. BMJ Open, 11(4), Article e045113. https://doi.org/10.1136/bmjopen-2020-045113

Objectives Respiratory infectious disease outbreaks pose a threat for loss of life, economic instability and social disruption. We conducted a systematic review of published econometric analyses to assess the direct and indirect costs of infectious r... Read More about Cost-effectiveness of emergency preparedness measures in response to infectious respiratory disease outbreaks: a systematic review and econometric analysis.

Barriers and facilitators to type 2 diabetes management in the Caribbean region: a qualitative systematic review (2020)
Journal Article
Nixon, A. L., Leonardi-Bee, J., Wang, H., & Chattopadhyay, K. (2021). Barriers and facilitators to type 2 diabetes management in the Caribbean region: a qualitative systematic review. JBI Evidence Synthesis, 19(5), 911-965. https://doi.org/10.11124/jbisrir-d-19-00424

Objective:The objective of this systematic review was to summarize the barriers and facilitators to type 2 diabetes mellitus management in the Caribbean region.Introduction:The prevalence of type 2 diabetes mellitus in the Caribbean is of significant... Read More about Barriers and facilitators to type 2 diabetes management in the Caribbean region: a qualitative systematic review.

Interventions for basal cell carcinoma of the skin (2020)
Journal Article
Thomson, J., Hogan, S., Leonardi-Bee, J., Williams, H. C., & Bath-Hextall, F. J. (2020). Interventions for basal cell carcinoma of the skin. Cochrane Library, 2020, Article CD003412. https://doi.org/10.1002/14651858.CD003412.pub3

Background: Basal cell carcinoma (BCC) is the commonest cancer affecting white-skinned individuals, and worldwide incidence is increasing. Although rarely fatal, BCC is associated with significant morbidity and costs. First-line treatment is usually... Read More about Interventions for basal cell carcinoma of the skin.

Quality of smoking cessation advice in guidelines of tobacco-related diseases: An updated systematic review (2020)
Journal Article
Ekezie, W., Murray, R. L., Agrawal, S., Bogdanovica, I., Britton, J., Leonardi-Bee, J., & Tobacco Advisory Group of the Royal College of Physicians. (2020). Quality of smoking cessation advice in guidelines of tobacco-related diseases: An updated systematic review. Clinical Medicine, 20(6), 551-559. https://doi.org/10.7861/clinmed.2020-0359

Tobacco smoking is a major risk factor for a wide range of diseases, and smoking cessation significantly reduces these risks. Clinical guidelines for diseases associated with smoking should therefore include guidance on smoking cessation. This review... Read More about Quality of smoking cessation advice in guidelines of tobacco-related diseases: An updated systematic review.

Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis. (2020)
Journal Article
Paskins, Z., Crawford-Manning, F., Cottrell, E., Corp, N., Wright, J., Jinks, C., …Sahota, O. (2020). Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis. BMJ Open, 10(11), Article e040634. https://doi.org/10.1136/bmjopen-2020-040634

OBJECTIVE: To explore the acceptability of different bisphosphonate regimens for the treatment of osteoporosis among patients, clinicians and managers, payers and academics.

DESIGN: A systematic review of primary qualitative studies. Seven databas... Read More about Acceptability of bisphosphonates among patients, clinicians and managers: a systematic review and framework synthesis..

Fetal safety of nicotine replacement therapy in pregnancy: systematic review and meta‐analysis (2020)
Journal Article
Taylor, L., Claire, R., Campbell, K., Coleman‐Haynes, T., Leonardi‐Bee, J., Chamberlain, C., …Coleman, T. (2021). Fetal safety of nicotine replacement therapy in pregnancy: systematic review and meta‐analysis. Addiction, 116(2), 239-277. https://doi.org/10.1111/add.15185

Background and aims: Smoking in pregnancy causes substantial avoidable harm to mothers and offspring; nicotine replacement therapy (NRT) may prevent this and is used to help women quit. A recently updated Cochrane review of randomised controlled tria... Read More about Fetal safety of nicotine replacement therapy in pregnancy: systematic review and meta‐analysis.

Experiences and views of women, children, and professionals regarding second-hand smoke exposure prevention in Middle Eastern countries: a qualitative systematic review protocol (2020)
Journal Article
Hassanein, Z., Langley, T., Murray, R., Bogdanovica, I., & Leonardi-Bee, J. (2021). Experiences and views of women, children, and professionals regarding second-hand smoke exposure prevention in Middle Eastern countries: a qualitative systematic review protocol. JBI Evidence Synthesis, 18(1), 222-228. https://doi.org/10.11124/JBISRIR-D-19-00248

Objective: This systematic review aims to identify and explore the experiences and views regarding secondhand smoke (SHS) exposure among women and children in the home, workplace, school, personal vehicles, and public places from the perspectives of... Read More about Experiences and views of women, children, and professionals regarding second-hand smoke exposure prevention in Middle Eastern countries: a qualitative systematic review protocol.

Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models (2020)
Journal Article
Akyea, R. K., Leonardi-Bee, J., Asselbergs, F. W., Patel, R. S., Durrington, P., Wierzbicki, A. S., …Weng, S. F. (2020). Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models. BMJ Open, 10(7), Article e034564. https://doi.org/10.1136/bmjopen-2019-034564

Introduction: Cardiovascular disease (CVD) is the leading cause of morbidity and mortality globally. With advances in early diagnosis and treatment of CVD and increasing life expectancy, more people are surviving initial CVD events. However, models t... Read More about Predicting major adverse cardiovascular events for secondary prevention: protocol for a systematic review and meta-analysis of risk prediction models.

Effectiveness and safety of Ayurvedic medicines in type-2 diabetes management: a systematic review protocol (2020)
Journal Article
Chattopadhyay, K., Panniyammakal, J., Biswas, T. K., Heinrich, M., Lewis, S. A., Greenfield, S. M., …Leonardi-Bee, J. (2020). Effectiveness and safety of Ayurvedic medicines in type-2 diabetes management: a systematic review protocol. JBI Evidence Synthesis, 18(11), 2380-2389. https://doi.org/10.11124/JBISRIR-D-19-00350

Objective: To evaluate and synthesize evidence on the effectiveness and safety of Ayurvedic medicines for managing type-2 diabetes (T2DM).

Introduction: Several randomized controlled trials (RCTs) have been conducted to assess the effectiveness an... Read More about Effectiveness and safety of Ayurvedic medicines in type-2 diabetes management: a systematic review protocol.

Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes (2020)
Journal Article
Jarrold, K., Helfer, B., Eskander, M., Crawley, H., Trabulsi, J., Caulfield, L. E., …Boyle, R. J. (2020). Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes. JAMA Pediatrics, 174(9), 874-881. https://doi.org/10.1001/jamapediatrics.2020.0578

Importance: Breast milk substitutes (BMS) are important nutritional products evaluated in clinical trials. Concerns have been raised about the risk of bias in BMS trials, the reliability of claims that arise from such trials, and the potential for B... Read More about Guidance for the Conduct and Reporting of Clinical Trials of Breast Milk Substitutes.

Pharmacological interventions for promoting smoking cessation during pregnancy (2020)
Journal Article
Claire, R., Chamberlain, C., Davey, M.-A., Leonardi-Bee, J., Cooper, S. E., Berlin, I., & Coleman, T. (2020). Pharmacological interventions for promoting smoking cessation during pregnancy. Cochrane Database of Systematic Reviews, Article CD010078. https://doi.org/10.1002/14651858.cd010078.pub3

Background: Tobacco smoking in pregnancy causes serious health problems for the developing fetus and mother. When used by non‐pregnant smokers, pharmacotherapies (nicotine replacement therapy (NRT), bupropion, and varenicline) are effective for incr... Read More about Pharmacological interventions for promoting smoking cessation during pregnancy.

Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis (2019)
Journal Article
Lansbury, L. E., Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J., & Shen Lim, W. (2020). Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis. Critical Care Medicine, 48(2), e98-e106. https://doi.org/10.1097/ccm.0000000000004093

Objective: Corticosteroids may be beneficial in sepsis but uncertainty remains over their effects in severe influenza. This systematic review updates the current evidence regarding corticosteroids in the treatment of influenza and examines the effect... Read More about Corticosteroids as Adjunctive Therapy in the Treatment of Influenza: An Updated Cochrane Systematic Review and Meta-analysis.

Incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia: a systematic review protocol (2019)
Journal Article
Khan, N., Chattopadhyay, K., & Leonardi-Bee, J. (2019). Incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia: a systematic review protocol. JBI Database of Systematic Reviews and Implementation Reports, 17(11), 2370-2377. https://doi.org/10.11124/jbisrir-d-18-00001

Objective: The objective of the systematic review is to summarize the incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia.

Introduction: Several studies have been conducted in South Asia on the incid... Read More about Incidence, prevalence, risk factors and health consequences of polypharmacy in adults in South Asia: a systematic review protocol.

Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study (2019)
Journal Article
Iyen, B., Qureshi, N., Leonardi-Bee, J., Kai, J., Akyea, R. K., Roderick, P., …Weng, S. (2019). Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study. Atherosclerosis, 287, 8-15. https://doi.org/10.1016/j.atherosclerosis.2019.05.017

Background and aims: Familial hypercholesterolaemia (FH) is a known major cause of premature heart disease. However, the risks of atherosclerotic disease in other vascular regions are less known. We determined the risk of major cardiovascular disease... Read More about Risk of cardiovascular disease outcomes in primary care subjects with familial hypercholesterolaemia: A cohort study.

Saliva cotinine concentrations in pregnant women who smoke and use nicotine patches (2019)
Journal Article
Claire, R., Coleman, T., Leonardi‐Bee, J., & Berlin, I. (2019). Saliva cotinine concentrations in pregnant women who smoke and use nicotine patches. Addiction, 114(9), 1651-1658. https://doi.org/10.1111/add.14662

Background and Aims: Due to concerns about increased exposure to nicotine, pregnant women using nicotine replacement therapy (NRT) to stop smoking are usually advised to stop using NRT if they relapse to smoking. This study investigated whether this... Read More about Saliva cotinine concentrations in pregnant women who smoke and use nicotine patches.

Corticosteroids as adjunctive therapy in the treatment of influenza (2019)
Journal Article
Lansbury, L., Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J., & Lim, W. S. (2019). Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database of Systematic Reviews, 2019(2), Article CD010406. https://doi.org/10.1002/14651858.CD010406.pub3

Background
Specific treatments for influenza are limited to neuraminidase inhibitors and adamantanes. Corticosteroids show evidence of benefit in sepsis and related conditions, most likely due to their anti‐inflammatory and immunomodulatory properti... Read More about Corticosteroids as adjunctive therapy in the treatment of influenza.

Promotion of breastfeeding by dental teams: A survey of early career dentists (2019)
Journal Article
Polglass, L., Leonardi-Bee, J., Morris, A., & Murray, R. (2019). Promotion of breastfeeding by dental teams: A survey of early career dentists. Journal of Health Visiting, 7(1), 24-29. https://doi.org/10.12968/johv.2019.7.1.24

Breastfeeding provides a range of positive health benefits for both mother and baby. Due to maternal exemption of dental charges, dentists have the access and opportunity to provide information to expectant and nursing mothers, and are in an optimal... Read More about Promotion of breastfeeding by dental teams: A survey of early career dentists.

Barriers and facilitators to type 2 diabetes management in the Caribbean region: a systematic review protocol (2018)
Journal Article
Nixon, A. L., Leonardi-Bee, J., & Chattopadhyay, K. (2019). Barriers and facilitators to type 2 diabetes management in the Caribbean region: a systematic review protocol. JBI Database of Systematic Reviews and Implementation Reports, 17(3), 267-272. https://doi.org/10.11124/JBISRIR-2017-003858

The objective of this systematic review is to summarize the barriers and facilitators to type 2 diabetes management in the Caribbean region.

Pre‐emptive and preventive opioids for postoperative pain in adults undergoing all types of surgery (2018)
Journal Article
Doleman, B., Leonardi-Bee, J., Lund, J. N., Heinink, T. P., Bhattacharjee, D., & Williams, J. P. (2018). Pre‐emptive and preventive opioids for postoperative pain in adults undergoing all types of surgery. Cochrane Database of Systematic Reviews, Article CD012624. https://doi.org/10.1002/14651858.CD012624.pub2

Background: Postoperative pain is a common consequence of surgery and can have deleterious effects. It has been suggested that the administration of opioid analgesia before a painful stimulus may improve pain control. This can be done in two ways. We... Read More about Pre‐emptive and preventive opioids for postoperative pain in adults undergoing all types of surgery.

Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults (2018)
Journal Article
Dinnes, J., Deeks, J. J., Chuchu, N., Matin, R. N., Wong, K. Y., Aldridge, R. B., Durack, A., Gulati, A., Chan, S. A., Johnston, L., Bayliss, S. E., Leonardi-Bee, J. O., Takwoingi, Y., Davenport, C., O'sullivan, C., Tehrani, H., & Williams, H. C. (2018). Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults. Cochrane Database of Systematic Reviews, 2018(12), Article CD011901. https://doi.org/10.1002/14651858.CD011901.pub2

© 2018 The Cochrane Collaboration. Background: Early accurate detection of all skin cancer types is important to guide appropriate management, to reduce morbidity and to improve survival. Basal cell carcinoma (BCC) is almost always a localised skin c... Read More about Visual inspection and dermoscopy, alone or in combination, for diagnosing keratinocyte skin cancers in adults.

Alcohol and the risk of pneumonia: a systematic review and meta-analysis (2018)
Journal Article
Simou, E., Britton, J., & Leonardi-Bee, J. (2018). Alcohol and the risk of pneumonia: a systematic review and meta-analysis. BMJ Open, 8(8), Article e022344. https://doi.org/10.1136/bmjopen-2018-022344

Objective: A systematic review and meta-analysis to estimate the magnitude of the association between alcohol consumption and the risk of community acquired pneumonia (CAP) in adults was undertaken.
Design: Systematic review and meta-analysis
Metho... Read More about Alcohol and the risk of pneumonia: a systematic review and meta-analysis.

Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health (2018)
Journal Article
Gibson, J. E., Ander, E. L., Cave, M., Bath-Hextall, F., Musah, A., & Leonardi-Bee, J. (2018). Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health. Population Health Metrics, 16(12), https://doi.org/10.1186/s12963-018-0168-2

Background: Long-term, low-level exposure to toxic elements in soil may be harmful to human health but large longitudinal cohort studies with sufficient follow-up time to study these effects are cost-prohibitive and impractical. Linkage of routinely... Read More about Linkage of national soil quality measurements to primary care medical records in England and Wales: a new resource for investigating environmental impacts on human health.

Long-term topical corticosteroid use and risk of skin cancer: a systematic review (2018)
Journal Article
Ratib, S., Burden-Teh, E., Leonardi-Bee, J., Harwood, C., & Bath-Hextall, F. (in press). Long-term topical corticosteroid use and risk of skin cancer: a systematic review. JBI Database of Systematic Reviews and Implementation Reports, 16(6), https://doi.org/10.11124/jbisrir-2017-003393

Objective: The objective of this systematic review was to synthesize available research evidence to determine the risk of skin cancer in patients with long-term use of topical corticosteroids (TCS).
Introduction: Topical corticosteroids are one of... Read More about Long-term topical corticosteroid use and risk of skin cancer: a systematic review.

Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study (2018)
Journal Article
Weng, S., Kai, J., Tranter, J., Leonardi-Bee, J., & Qureshi, N. (2018). Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study. Atherosclerosis, 274, 54-60. https://doi.org/10.1016/j.atherosclerosis.2018.04.037

Background and Aims: Familial hypercholesterolaemia (FH) is a major cause of premature heart disease but remains unrecognised in most patients. This study investigated if a systematic primary care-based approach to identify and manage possible FH imp... Read More about Improving identification & management of familial hypercholesterolaemia in primary care: pre- and post-intervention study.

Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings (2018)
Journal Article
Qureshi, N., Weng, S. F., Tranter, J. A., Da Silva, M. L., Kai, J., & Leonardi-Bee, J. (2018). Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings. Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012985

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

The purpose of this review is to assess the effectiveness of interventions to systematically improve identification of FH in non-specialist settings compared t... Read More about Strategies for identifying familial hypercholesterolaemia in non-specialist clinical settings.

Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol) (2018)
Journal Article
Doleman, B., Leonardi-Bee, J., Heinink, T. P., Lund, J., & Williams, J. P. (2018). Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol). Cochrane Database of Systematic Reviews, 3, https://doi.org/10.1002/14651858.CD012978

This is a protocol for a Cochrane Review (Intervention). The objectives are as follows:

To evaluate in adult participants undergoing all types of surgery, the effects of pre-emptive and preventive non-steroidal anti-inflammatory drugs (NSAIDs) com... Read More about Pre-emptive and preventive NSAIDs for postoperative pain in adults undergoing all types of surgery (Protocol).

Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis (2018)
Journal Article
Garcia-Larsen, V., Ierodiakonou, D., Jarrold, K., Cunha, S., Chivinge, J., Robinson, Z., Geoghegan, N., Ruparelia, A., Devani, P., Trivella, M., Leonardi-Bee, J., & Boyle, R. J. (2018). Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis. PLoS Medicine, 15(2), Article e1002507. https://doi.org/10.1371/journal.pmed.1002507

Background: There is uncertainty about the influence of diet during pregnancy and infancy on a child’s immune development. We assessed whether variations in maternal or infant diet can influence risk of allergic or autoimmune disease.
Methods and fi... Read More about Diet during pregnancy and infancy, and risk of allergic or autoimmune disease: a systematic review and meta-analysis.

Alcohol and the risk of sleep apnoea: a systematic review and meta-analysis (2018)
Journal Article
Simou, E., Britton, J., & Leonardi-Bee, J. (in press). Alcohol and the risk of sleep apnoea: a systematic review and meta-analysis. Sleep Medicine, 42, https://doi.org/10.1016/j.sleep.2017.12.005

Objective:
A systematic review and meta-analysis of the association between alcohol consumption and risk of sleep apnoea in adults.

Methods:
We searched Medline, EMBASE and Web of Science databases from 1985 to 2015 for comparative epidemiologic... Read More about Alcohol and the risk of sleep apnoea: a systematic review and meta-analysis.

The effect of alcohol consumption on the risk of ARDS: a systematic review and meta-analysis (2017)
Journal Article
Simou, E., Leonardi-Bee, J., & Britton, J. (in press). The effect of alcohol consumption on the risk of ARDS: a systematic review and meta-analysis. Chest, https://doi.org/10.1016/j.chest.2017.11.041

BACKGROUND: To conduct a systematic review and meta-analysis evaluating the association between alcohol consumption and the risk of ARDS in adults.
METHODS: Medline, EMBASE and Web of Science were searched to identify observational studies evaluatin... Read More about The effect of alcohol consumption on the risk of ARDS: a systematic review and meta-analysis.

Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe (2017)
Journal Article
Alimi, Y., Lim, W., Lansbury, L. E., Leonardi-Bee, J., & Nguyen-Van-Tam, J. S. (2017). Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe. Journal of Clinical Virology, 95, https://doi.org/10.1016/j.jcv.2017.07.019

Community-acquired pneumonia (CAP) is an important respiratory disease and the fifth leading cause of mortality in Europe. The development of molecular diagnostic tests has highlighted the contributions of respiratory viruses to the aetiology of CAP,... Read More about Systematic review of respiratory viral pathogens identified in adults with community-acquired pneumonia in Europe.

Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol (2016)
Journal Article
Ratib, S., Burden-Teh, E., Leonardi-Bee, J., Harwood, C., & Bath-Hextall, F. (2016). Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol. JBI Database of Systematic Reviews and Implementation Reports, 14(12), https://doi.org/10.11124/JBISRIR-2016-003226

Review question/objective: The objective of this systematic review is to synthesize the best available research evidence to determine the risk of skin cancer in patients on long-term use of topical corticosteroids. Specifically the review question is... Read More about Long-term topical corticosteroid use and risk of skin cancer: a systematic review protocol.

English stop-smoking services: one-year outcomes (2016)
Journal Article
Bauld, L., Hiscock, R., Dobbie, F., Aveyard, P., Coleman, T., Leonardi-Bee, J., …McEwan, A. (2016). English stop-smoking services: one-year outcomes. International Journal of Environmental Research and Public Health, 13(12), Article 1175. https://doi.org/10.3390/ijerph13121175

The UK is a global leader in stop-smoking support—providing free behavioral support and cessation medication via stop smoking services (SSS) without charge to smokers. This study aimed to explore the client and service characteristics associated with... Read More about English stop-smoking services: one-year outcomes.

Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis (2016)
Journal Article
Ierodiakonou, D., Garcia-Larsen, V., Logan, A., Groome, A., Cunha, S., Chivinge, J., …Boyle, R. J. (2016). Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis. Journal of the American Medical Association, 316(11), 1181-1192. https://doi.org/10.1001/jama.2016.12623

Importance: Timing of introduction of allergenic foods to the infant diet may influence the risk of allergic or autoimmune disease, but the evidence for this has not been comprehensively synthesized.

Objective: To systematically review and meta-a... Read More about Timing of allergenic food to the introduction to the infant diet and risk of allergic or autoimmune disease: a systematic review and meta-analysis.

Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit) (2016)
Presentation / Conference Contribution
Naughton, F., Foster, K., Emery, J., Cooper, S., Sutton, S., Leonardi-Bee, J., Jones, M., Ussher, M., Whitemore, R., Leighton, M., Montgomery, A., Parrott, S., & Coleman, T. (2016, August). Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit). Presented at European Health Psychology Society and British Psychological Society Division of Health Psychology Conference 2016 (EHPS/DHP 2016)

Background: Text message cessation programmes have potential to change smoking behaviour during pregnancy but their effectiveness is unknown. This study aimed to estimate key parameters, including effectiveness and cost-effectiveness, for delivering... Read More about Multicentre, randomised controlled trial of a low-cost smoking cessation text message intervention for pregnant smokers (MiQuit).

Smoking in movies and smoking initiation in adolescents: systematic review and meta-analysis (2016)
Journal Article
Leonardi-Bee, J., Nderi, M., & Britton, J. (in press). Smoking in movies and smoking initiation in adolescents: systematic review and meta-analysis. Addiction, 111(10), https://doi.org/10.1111/add.13418

Background and aims: Preventing young people from initiating smoking is a vital public health objective. There is strong evidence that exposure to smoking imagery in movies is associated with an increased risk of smoking uptake. However, the estimate... Read More about Smoking in movies and smoking initiation in adolescents: systematic review and meta-analysis.

Corticosteroids as adjunctive therapy in the treatment of influenza (2016)
Journal Article
Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J., & Lim, W. S. (2016). Corticosteroids as adjunctive therapy in the treatment of influenza. Cochrane Database of Systematic Reviews, Article CD010406. https://doi.org/10.1002/14651858.CD010406.pub2

Background: Specific treatments for influenza are limited to neuraminidase inhibitors and adamantanes. Corticosteroids show evidence of benefit in sepsis and related conditions, most likely due to their anti-inflammatory and immunomodulatory properti... Read More about Corticosteroids as adjunctive therapy in the treatment of influenza.

Small area synthetic estimates of smoking prevalence during pregnancy in England (2015)
Journal Article
Szatkowski, L., Fahy, S., Coleman, T., Taylor, J., Twigg, L., Moon, G., & Leonardi-Bee, J. (2015). Small area synthetic estimates of smoking prevalence during pregnancy in England. Population Health Metrics, 13(34), https://doi.org/10.1186/s12963-015-0067-8

Background: Complete and accurate data on maternal smoking prevalence during pregnancy are not available at a local geographical scale in England. We employ a synthetic estimation approach to predict the expected prevalence of smoking during pregnanc... Read More about Small area synthetic estimates of smoking prevalence during pregnancy in England.

Self‐help educational booklets for the prevention of smoking relapse following smoking cessation treatment: a randomized controlled trial (2015)
Journal Article
Maskrey, V., Blyth, A., Brown, T. J., Barton, G. R., Notley, C., Aveyard, P., …Leonardi-Bee, J. (2015). Self‐help educational booklets for the prevention of smoking relapse following smoking cessation treatment: a randomized controlled trial. Addiction, 110(12), https://doi.org/10.1111/add.13080

Aims: Most people who quit smoking for a short term will return to smoking again in 12 months. We tested whether self-help booklets can reduce relapse in short-term quitters after receiving behavioural and pharmacological cessation treatment.

Des... Read More about Self‐help educational booklets for the prevention of smoking relapse following smoking cessation treatment: a randomized controlled trial.

Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline (2015)
Journal Article

Background and aims Varenicline increases the likelihood of long-term abstinence following a quit attempt. It has been suggested that 1) part of its benefit arises from ‘recruiting into abstinence’ smokers who are not able to stop on the target quit... Read More about Abstinence and relapse among smokers who use varenicline in a quit attempt-a pooled analysis of randomized controlled trials: Relapse and abstinence in smokers treated with varenicline.

Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis (2014)
Journal Article
Rodrigo, C., Leonardi-Bee, J., Nguyen-Van-Tam, J. S., & Lim, W. S. (2015). Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis. Journal of Infectious Diseases, 212(2), 183-194. https://doi.org/10.1093/infdis/jiu645

Background: Most studies have reported that corticosteroid therapy adversely influences influenza-related outcomes.

Methods: Electronic databases were searched from inception to March 2013 for experimental and observational studies investigating s... Read More about Effect of Corticosteroid Therapy on Influenza-Related Mortality: A Systematic Review and Meta-analysis.

Does looped nasogastric tube feeding improve nutritional delivery for patients with dysphagia after acute stroke? A randomised controlled trial (2010)
Journal Article
Beavan, J., Paul Conroy, S., Harwood, R., Gladman, J. R., Leonardi-Bee, J., Sach, T., Bowling, T., Sunman, W., & Gaynor, C. (2010). Does looped nasogastric tube feeding improve nutritional delivery for patients with dysphagia after acute stroke? A randomised controlled trial. Age and Ageing, 39(5), 624-630. https://doi.org/10.1093/ageing/afq088

Background: nasogastric tube (NGT) feeding is commonly used after stroke, but its effectiveness is limited by frequent dislodgement.

Objective: the objective of the study was to evaluate looped NGT feeding in acute stroke patients with dysphagia.... Read More about Does looped nasogastric tube feeding improve nutritional delivery for patients with dysphagia after acute stroke? A randomised controlled trial.