Outputs (33)

Obesity in Nigerian Adults and the Associated Cause and Impact on the Population (2022)
Journal Article
Ellecom, J. B., Shaw, I., & Adams, G. G. (2022). Obesity in Nigerian Adults and the Associated Cause and Impact on the Population. Journal of Diabetes Research Reviews & Reports, 4(4), 1-11. https://doi.org/10.47363/JDRR/2022%284%29165

Background: Obesity has been on the rise in developed and developing countries such as Nigeria. Data from the WHO demonstrated the prevalence of obesity increased by 15% between 2002 and 2016 in Nigeria. Here, we examine the rate of obesity in Nigeri... Read More about Obesity in Nigerian Adults and the Associated Cause and Impact on the Population.

Physical activity pre-and during pregnancy and gestational diabetes onset across multi-ethnic pregnant populations: a systematic review and meta-analysis of epidemiological studies (2022)
Journal Article
Alaslani, H., Shaw, I., & Adams, G. (2023). Physical activity pre-and during pregnancy and gestational diabetes onset across multi-ethnic pregnant populations: a systematic review and meta-analysis of epidemiological studies. MOJ Public Health, 11(1), 28-32. https://doi.org/10.15406/mojph.2022.11.00370

Background: Gestational diabetes mellitus (GDM) is a common complication during pregnancy and is associated with adverse pregnancy outcomes and maternal and neonatal risks. Lifestyle intervention through physical activity is generally similar to diet... Read More about Physical activity pre-and during pregnancy and gestational diabetes onset across multi-ethnic pregnant populations: a systematic review and meta-analysis of epidemiological studies.

Motor Developmental Outcomes in Children Exposed to Maternal Diabetes During Pregnancy: A Systematic Review and Meta-Analysis (2021)
Journal Article
Arabiat, D., Jabery, M. A., Kemp, V., Jenkins, M., Whitehead, L. C., & Adams, G. (2021). Motor Developmental Outcomes in Children Exposed to Maternal Diabetes During Pregnancy: A Systematic Review and Meta-Analysis. International Journal of Environmental Research and Public Health, 18(4), Article 1699. https://doi.org/10.3390/ijerph18041699

Studies on the association of maternal diabetes with motor development in children provide inconsistent findings. We searched MEDLINE/PubMed, EMBASE, Emcare, PsycINFO, and Google Scholar databases for primary observational, case–control, or cohort st... Read More about Motor Developmental Outcomes in Children Exposed to Maternal Diabetes During Pregnancy: A Systematic Review and Meta-Analysis.

Probing the effect of aroma compounds on the hydrodynamic properties of mucin glycoproteins (2020)
Journal Article
Dinu, V., MacCalman, T., Yang, N., Adams, G. G., Yakubov, G. E., Harding, S. E., & Fisk, I. D. (2020). Probing the effect of aroma compounds on the hydrodynamic properties of mucin glycoproteins. European Biophysics Journal, 49(8), 799-808. https://doi.org/10.1007/s00249-020-01475-4

© 2020, The Author(s). Aroma compounds are diverse low molecular weight organic molecules responsible for the flavour of food, medicines or cosmetics. Natural and artificial aroma compounds are manufactured and used by the industry to enhance the fla... Read More about Probing the effect of aroma compounds on the hydrodynamic properties of mucin glycoproteins.

Food biotechnology (2020)
Journal Article
Foster, T., Adams, G., di Bari, V., Connerton, I., Gould, J., Gouseti, O., …Yakubov, G. (2020). Food biotechnology. Current Opinion in Chemical Engineering, 30, 53-59. https://doi.org/10.1016/j.coche.2020.08.006

We investigate recent advances in the Chemical Engineering aspects of food structuring agents and macronutrients: carbohydrates, proteins and lipids, and also the fate of food upon ingestion. Prebiotic effects on host-microbe interactions enable impr... Read More about Food biotechnology.

Effectiveness of Community Health Worker-led Diabetes Self-Management Education on Type 2 diabetes patients: A Systematic Review and Meta-Analysis (2020)
Journal Article
Amagyei, A., Meal, A., Shaw, I., & Adams, G. G. (2020). Effectiveness of Community Health Worker-led Diabetes Self-Management Education on Type 2 diabetes patients: A Systematic Review and Meta-Analysis. International Journal of Diabetes, 1(2), 40-50

Objective: Community Health Workers are important in building individual and community capacity through outreach, community education, informal counselling, social support and advocacy programs, which enhance health knowledge and self-sufficiency. Ou... Read More about Effectiveness of Community Health Worker-led Diabetes Self-Management Education on Type 2 diabetes patients: A Systematic Review and Meta-Analysis.

Is Liraglutide a Safe and Effective Medication to Treat Hyperglycaemia?: A Systematic Review (2020)
Journal Article
Al Oneze, A., Jiwan, S. I., Gyasi-Antw, P., Meal, A., & Adams, G. G. (2020). Is Liraglutide a Safe and Effective Medication to Treat Hyperglycaemia?: A Systematic Review. Annals of Clinical Diabetes and Endocrinology, 3(2), Article 1017

Background: The aim of this systematic review is to examine the effectiveness of Liraglutide on glycemic control and Systolic Blood Pressure (SBP) in patients with Type 2 Diabetes (T2D) mellitus and to investigate whether Liraglutide leads to any Gas... Read More about Is Liraglutide a Safe and Effective Medication to Treat Hyperglycaemia?: A Systematic Review.

Effect of Lifestyle and Diet on Gestational Diabetes (GDM) in South Asian Women: A Systematic Review (2020)
Journal Article
Naseer, N., Shaw, I., & Adams, G. (2020). Effect of Lifestyle and Diet on Gestational Diabetes (GDM) in South Asian Women: A Systematic Review. Journal of Diabetes & Metabolic Syndrome, 3(1), Article 100010

Background: Evidence suggests that all forms of diabetes are on the increase, especially Gestational Diabetes Mellitus (GDM), which increases the risk of maternal and neonatal morbidities. However, the global effect of diet (HA) and lifestyle (PA) of... Read More about Effect of Lifestyle and Diet on Gestational Diabetes (GDM) in South Asian Women: A Systematic Review.

Characterisation of the molecular properties of scleroglucan as an alternative rigid rod molecule to xanthan gum for oropharyngeal dysphagia (2019)
Journal Article
Li, X., Lu, Y., Adams, G. G., Zobel, H., Ballance, S., Wolf, B., & Harding, S. E. (2020). Characterisation of the molecular properties of scleroglucan as an alternative rigid rod molecule to xanthan gum for oropharyngeal dysphagia. Food Hydrocolloids, 101, 1-9. https://doi.org/10.1016/j.foodhyd.2019.105446

Scleroglucan, a neutral β(1–3) glucan with β(1–6) glucan branches every third residue, is being considered as an alternative rod-like, shear thinning high molecular weight β-glucan based polysaccharide to xanthan gum for the management of patients wi... Read More about Characterisation of the molecular properties of scleroglucan as an alternative rigid rod molecule to xanthan gum for oropharyngeal dysphagia.

Relationship between Lipohypertrophy, Injection Techniques and Education in adults with Type 2 Diabetes: A Systematic Review (2019)
Journal Article
Thomas, J., Meal, A., & Adams, G. G. (2019). Relationship between Lipohypertrophy, Injection Techniques and Education in adults with Type 2 Diabetes: A Systematic Review. Journal of Diabetes and Treatment, 4(2), Article 1074. https://doi.org/10.29011/2574-7568.001074

Introduction: This systematic review examines Lipohypertrophy (LH) in patients presenting with Type 1/2 Diabetes (T1/2DM) in relation to education and injection techniques. LH is a condition, which occurs in diabetes individuals at injection sights.... Read More about Relationship between Lipohypertrophy, Injection Techniques and Education in adults with Type 2 Diabetes: A Systematic Review.

Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour (2019)
Journal Article
Dinu, V., Yakubov, G. E., Lim, M., Hurst, K., Adams, G. G., Harding, S. E., & Fisk, I. D. (2019). Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour. International Journal of Biological Macromolecules, 138, 831-836. https://doi.org/10.1016/j.ijbiomac.2019.07.148

To reduce animal testing, there is a need to develop novel in-vitro models for evaluating the retention of bioactive compounds in food and pharmaceutical products. Here, a mucus-mimetic platform was developed through a one-step approach based on enca... Read More about Mucin immobilization in calcium alginate: A possible mucus mimetic tool for evaluating mucoadhesion and retention of flavour.

Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity (2019)
Journal Article
Dinu, V., Gillis, R. B., MacCalman, T., Lim, M., Adams, G. G., Harding, S. E., & Fisk, I. D. (2019). Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity. Food Biophysics, 14(3), 278-286. https://doi.org/10.1007/s11483-019-09574-2

Submaxillary mucin is a major component that defines the makeup and functionality of saliva. Understanding its structure and function during food intake is key to designing appropriate strategies for enhancing the delivery of flavour. In the present... Read More about Submaxillary Mucin: its Effect on Aroma Release from Acidic Drinks and New Insight into the Effect of Aroma Compounds on its Macromolecular Integrity.

The practice of glycaemic control in intensive care units: A multicentre survey of nursing and medical professionals (2019)
Journal Article
Fernández‐Méndez, R., Harvey, D. J. R., Windle, R., & Adams, G. G. (2019). The practice of glycaemic control in intensive care units: A multicentre survey of nursing and medical professionals. Journal of Clinical Nursing, 28(11-12), 2088-2100. https://doi.org/10.1111/jocn.14774

Aims and objectives To determine the views of nurses and physicians working in intensive care units (ICU) about the aims of glycaemic control and use of their protocols. Background Evidence about the optimal aims and methods for glycaemic contro... Read More about The practice of glycaemic control in intensive care units: A multicentre survey of nursing and medical professionals.

Outcomes of mindfulness-based stress reduction and mindfulness-based cognitive therapy in adults with diabetes: a systematic review (2018)
Journal Article
Mason, J., Meal, A., Shaw, I., & Adams, G. G. (in press). Outcomes of mindfulness-based stress reduction and mindfulness-based cognitive therapy in adults with diabetes: a systematic review. Journal of Diabetes and Treatment, 2018(2), https://doi.org/10.29011/2574-7568.000049

Objectives: Diabetes Mellitus (DM) is a global and progressive chronic medical condition with increasing prevalence and associated costs throughout the world. Psychological problems are common in people with DM and when they co-occur are associated w... Read More about Outcomes of mindfulness-based stress reduction and mindfulness-based cognitive therapy in adults with diabetes: a systematic review.

Characterisation of insulin analogues therapeutically available to patients (2018)
Journal Article
Adams, G. G., Meal, A., Morgan, P. S., Alzahrani, Q. E., Zobel, H., Lithgo, R., …Chayen, N. (2018). Characterisation of insulin analogues therapeutically available to patients. PLoS ONE, 13(3), Article e0195010. https://doi.org/10.1371/journal.pone.0195010

The structure and function of clinical dosage insulin and its analogues were assessed. This included ‘native insulins’ (human recombinant, bovine, porcine), ‘fast-acting analogues’ (aspart, glulisine, lispro) and ‘slow-acting analogues’ (glargine, de... Read More about Characterisation of insulin analogues therapeutically available to patients.

Glargine and degludec: solution behaviour of higher dose synthetic insulins (2017)
Journal Article
Adams, G. G., Alzahrani, Q., Jiwani, S. I., Meal, A., Morgan, P. S., Coffey, F., …Gillis, R. B. (2017). Glargine and degludec: solution behaviour of higher dose synthetic insulins. Scientific Reports, 7(1), Article 7287. https://doi.org/10.1038/s41598-017-06642-w

Single, double and triple doses of the synthetic insulins glargine and degludec currently used in patient therapy are characterised using macromolecular hydrodynamic techniques (dynamic light scattering and analytical ultracentrifugation) in an attem... Read More about Glargine and degludec: solution behaviour of higher dose synthetic insulins.

Health beliefs predict self-care practices and glycaemic control in Malaysian patients with insulin-treated diabetes: a longtitudal study (2017)
Journal Article
Aris, A., Blake, H., & Adams, G. (2017). Health beliefs predict self-care practices and glycaemic control in Malaysian patients with insulin-treated diabetes: a longtitudal study. Malaysian Journal of Public Health Medicine, 17(2), 80-89

The practice of diabetes self-care plays an important role in achieving and maintaining good glycaemic control. However, not all patients with insulin-treated diabetes engage in their self-care activities. There is some evidence that self-care practi... Read More about Health beliefs predict self-care practices and glycaemic control in Malaysian patients with insulin-treated diabetes: a longtitudal study.

Dietitians' practice in giving carbohydrate advice in the management of type 2 diabetes: a mixed methods study (2016)
Journal Article
McArdle, P. D., Greenfield, S. M., Avery, A., Adams, G. G., & Gill, P. S. (in press). Dietitians' practice in giving carbohydrate advice in the management of type 2 diabetes: a mixed methods study. Journal of Human Nutrition and Dietetics, 30(3), https://doi.org/10.1111/jhn.12436

Background: Carbohydrate is accepted as the principal nutrient affecting blood glucose in diabetes; however, current guidelines are unable to specify the optimal quantity of carbohydrate for glycaemic control. No studies exist that describe current p... Read More about Dietitians' practice in giving carbohydrate advice in the management of type 2 diabetes: a mixed methods study.

Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein (2016)
Journal Article
Abdelhameed, A. S., Morris, G. A., Almutairi, F., Adams, G. G., Duvivier, P., Conrath, K., & Harding, S. E. (in press). Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein. Scientific Reports, 6(1), 1-11. https://doi.org/10.1038/srep35588

The structural integrity of meningococcal native, micro-fluidized and activated capsular polysaccharides and their glycoconjugates – in the form most relevant to their potential use as vaccines (dilute solution) - have been investigated with respect... Read More about Solution conformation and flexibility of capsular polysaccharides from Neisseria meningitidis and glycoconjugates with the tetanus toxoid protein.

Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions (2016)
Journal Article
Sarangapani, P. S., Weaver, J., Parupudi, A., Besong, T. M., Adams, G. G., Harding, S. E., …Pathak, J. A. (2016). Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions. Journal of Pharmaceutical Sciences, 105(12), https://doi.org/10.1016/j.xphs.2016.08.020

The role of antibody structure (conformation) in solution rheology is probed. It is demonstrated here that pH-dependent changes in the tertiary structure of 2 mAb solutions lead to viscoelasticity and not merely a shear viscosity (η) increase. Steady... Read More about Both reversible self-association and structural changes underpin molecular viscoelasticity of mAb solutions.

Genetic improvement of tomato by targeted control of fruit softening (2016)
Journal Article
Uluisik, S., Chapman, N. H., Smith, R., Poole, M., Adams, G., Gillis, R. B., …Seymour, G. B. (2016). Genetic improvement of tomato by targeted control of fruit softening. Nature Biotechnology, 34, 950-952. https://doi.org/10.1038/nbt.3602

Controlling the rate of softening to extend shelf life was a key target for researchers engineering genetically modified (GM) tomatoes in the 1990s, but only modest improvements were achieved. Hybrids grown nowadays contain 'non-ripening mutations' t... Read More about Genetic improvement of tomato by targeted control of fruit softening.

Molecular weight analysis of starches: which technique? (2016)
Journal Article
Harding, S. E., Adams, G. G., & Gillis, R. B. (2016). Molecular weight analysis of starches: which technique?. Starch/Stärke, 68(9-10), https://doi.org/10.1002/star.201600042

A number of methods are available to researchers for estimating molecular weights (molar masses) and molecular weight distributions of starches − or those in solution, using an appropriate solvent/solubilisation protocol. We outline the methods avail... Read More about Molecular weight analysis of starches: which technique?.

Aspects of the analytical ultracentrifuge determination of the molar mass distribution of polysaccharides (2016)
Book Chapter
Harding, S. E., Adams, G. G., Gillis, R. B., Almutairi, F. M., & Morris, G. A. (2016). Aspects of the analytical ultracentrifuge determination of the molar mass distribution of polysaccharides. In S. Uchiyama, F. Arisaka, W. F. Stafford, & T. M. Laue (Eds.), Analytical ultracentrifugation: instrumentation, software and applications (375-386). Springer. https://doi.org/10.1007/978-4-431-55985-6_18

Molar mass or ‘molecular weight’ is one of the most fundamental parameters describing a macromolecule. Because of their polydisperse nature, polysaccharides are usually described by distributions of molar mass. SEC-MALS (size exclusion chromatography... Read More about Aspects of the analytical ultracentrifuge determination of the molar mass distribution of polysaccharides.

A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate (2016)
Journal Article
Abdelhameed, A. S., Adams, G. G., Morris, G. A., Almutairi, F. M., Duvivier, P., Conrath, K., & Harding, S. E. (2016). A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate. Scientific Reports, 6(1), Article 22208. https://doi.org/10.1038/srep22208

Three important physical properties which may affect the performance of glycoconjugate vaccines against serious disease are molar mass (molecular weight), heterogeneity (polydispersity), and conformational flexibility in solution. The dilute solution... Read More about A glycoconjugate of Haemophilus influenzae Type b capsular polysaccharide with tetanus toxoid protein: hydrodynamic properties mainly influenced by the carbohydrate.

The effectiveness of information-motivation-behavioural skills model-based diabetes self-management education among patients with type 2 diabetes in Jordan (IMB-DSME): trial protocol (2015)
Presentation / Conference Contribution
Albelbisi, Z., Adams, G. G., Windle, R., & Blake, H. (2015). The effectiveness of information-motivation-behavioural skills model-based diabetes self-management education among patients with type 2 diabetes in Jordan (IMB-DSME): trial protocol.

Abstract for UKSBM conference: Background: According to the World Health Organization in 2014, 9% of adults over 18 years old are diagnosed with diabetes and more than 1.5 million deaths occur directly by diabetes in low and middle-income countries.... Read More about The effectiveness of information-motivation-behavioural skills model-based diabetes self-management education among patients with type 2 diabetes in Jordan (IMB-DSME): trial protocol.

Application of recent advances in hydrodynamic methods for characterising mucins in solution (2015)
Journal Article
Almutairi, F. M., Cifre, J. H., Adams, G. G., Kök, M. S., Mackie, A. R., de la Torre, J. G., & Harding, S. E. (2016). Application of recent advances in hydrodynamic methods for characterising mucins in solution. European Biophysics Journal, 45(1), 45-54. https://doi.org/10.1007/s00249-015-1075-0

Mucins are the primary macromolecular component of mucus—nature’s natural lubricant—although they are poorly characterised heterogeneous substances. Recent advances in hydrodynamic methodology now offer the opportunity for gaining a better understand... Read More about Application of recent advances in hydrodynamic methods for characterising mucins in solution.

Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins (2015)
Book Chapter
Harding, S. E., Adams, G. G., Almutairi, F., Alzahrani, Q., Erten, T., Samil Kök, M., & Gillis, R. B. (2015). Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins. In Analytical Ultracentrifugation (391-439). Academic Press. https://doi.org/10.1016/bs.mie.2015.06.043

Although like proteins, polysaccharides are synthesized by enzymes, unlike proteins there is no template. This means that they are polydisperse, do not generally have compact folded structures, and are often very large with greater nonideality behavi... Read More about Ultracentrifuge Methods for the Analysis of Polysaccharides, Glycoconjugates, and Lignins.

The effectiveness of Information- Motivation-Behavioural skills model-based Diabetes Self-Management Education among patients with type 2 diabetes in Jordan (IMB-DSME): trial protocol (2015)
Presentation / Conference Contribution
Albelbisi, Z., Adams, G., Windle, R., & Blake, H. (2015, August). The effectiveness of Information- Motivation-Behavioural skills model-based Diabetes Self-Management Education among patients with type 2 diabetes in Jordan (IMB-DSME): trial protocol. Paper presented at American Association of Diabetes Educators Annual Meeting, New Orleans, USA

Hydrodynamic characterisation of chitosan and its interaction with two polyanions: DNA and xanthan (2014)
Journal Article
Almutairi, F. M., Erten, T., Adams, G. G., Hayes, M., McLoughlin, P., Kök, M. Ş., …Harding, S. E. (2015). Hydrodynamic characterisation of chitosan and its interaction with two polyanions: DNA and xanthan. Carbohydrate Polymers, 122, https://doi.org/10.1016/j.carbpol.2014.09.090

Chitosan, a soluble polycationic derivative of insoluble chitin, has been widely considered for use in the food, cosmetic and pharmaceutical industries. Commercial (“C”) and in-house laboratory (“L”) prepared chitosan samples extracted from crustaceo... Read More about Hydrodynamic characterisation of chitosan and its interaction with two polyanions: DNA and xanthan.

On hydrodynamic methods for the analysis of the sizes and shapes of polysaccharides in dilute solution: a short review (2014)
Journal Article
Morris, G. A., Adams, G. G., & Harding, S. E. (2014). On hydrodynamic methods for the analysis of the sizes and shapes of polysaccharides in dilute solution: a short review. Food Hydrocolloids, 42, https://doi.org/10.1016/j.foodhyd.2014.04.014

Background: Polysaccharides and their derivatives are increasingly being used by the food, cosmetic and pharmaceutical industries: physical properties like size and conformation are important contributors to their performance. Discussion: Here the u... Read More about On hydrodynamic methods for the analysis of the sizes and shapes of polysaccharides in dilute solution: a short review.

Comparative heterogeneity, molecular weights and viscosities of xanthans of different pyruvate and acetate content (2014)
Journal Article
Erten, T., Adams, G. G., Foster, T. J., & Harding, S. E. (2014). Comparative heterogeneity, molecular weights and viscosities of xanthans of different pyruvate and acetate content. Food Hydrocolloids, 42, https://doi.org/10.1016/j.foodhyd.2014.04.012

Introduction: The bacterial exopolysaccharide xanthan is a well-known hydrocolloid, with a high viscosity deriving from its large molecular weight and volume. Materials and methods: Four different xanthans deriving from Xanthomanas campestris -two w... Read More about Comparative heterogeneity, molecular weights and viscosities of xanthans of different pyruvate and acetate content.

“Medioglycaemia”: a new concept in glycaemic control in intensive care (ICU) units? (2012)
Journal Article
Tomlinson, V. H., Langley, J., Meal, A. G., & Adams, G. G. (2012). “Medioglycaemia”: a new concept in glycaemic control in intensive care (ICU) units?. Journal of Diabetes Mellitus, 25(4), https://doi.org/10.4236/jdm.2012.24056

Introduction: Critically ill patients can experience stress-induced hyperglycaemia. Glycaemic control therapy (GCT) is administered to control patients’ blood glycaemic levels and reduce the incidence of infection, myocardial infarctions and organ fa... Read More about “Medioglycaemia”: a new concept in glycaemic control in intensive care (ICU) units?.

Diabetes health-beliefs, self-care practices and glycaemic control among Malaysian young adults with diabetes (2011)
Journal Article
Aris, A., Blake, H., & Adams, G. (2011). Diabetes health-beliefs, self-care practices and glycaemic control among Malaysian young adults with diabetes. Journal of Nursing Referência (Revista de Enfermagem Referência), 4(Supp),

Self-care practices and glycaemic control remain suboptimal among young adults with diabetes. One of the known factors to influence self-care behaviours is health beliefs. Targeting health beliefs through diabetes education facilitates individual’s d... Read More about Diabetes health-beliefs, self-care practices and glycaemic control among Malaysian young adults with diabetes.