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Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists (2024)
Journal Article
Cullum, S. A., Platt, S., Dale, N., Isaac, O. C., Wragg, E. S., Soave, M., …Hill, S. J. (2024). Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists. Communications Biology, 7(1), Article 417. https://doi.org/10.1038/s42003-024-06128-2

The concept of agonist-independent signalling that can be attenuated by inverse agonists is a fundamental element of the cubic ternary complex model of G protein-coupled receptor (GPCR) activation. This model shows how a GPCR can exist in two conform... Read More about Mechano-sensitivity of β2-adrenoceptors enhances constitutive activation of cAMP generation that is inhibited by inverse agonists.

Expression of Cathepsin D in early-stage breast cancer and its prognostic and predictive value (2024)
Journal Article
Alhudiri, I., Nolan, C., Ellis, I., Elzagheid, A., Green, A., & Chapman, C. (2024). Expression of Cathepsin D in early-stage breast cancer and its prognostic and predictive value. Breast Cancer Research and Treatment, https://doi.org/10.1007/s10549-024-07293-y

Purpose Cathepsin D is a proteolytic enzyme that is normally localized in the lysosomes and is involved in the malignant progression of breast cancer. There are conflicting results regarding Cathepsin D significance as prognostic and predictor marke... Read More about Expression of Cathepsin D in early-stage breast cancer and its prognostic and predictive value.

Load transfer mechanisms for capped and uncapped non-displacement piles above tunnels: a centrifuge modelling study (2024)
Journal Article
Tang, C., Franza, A., Xu, J., & Marshall, A. M. (2024). Load transfer mechanisms for capped and uncapped non-displacement piles above tunnels: a centrifuge modelling study. Géotechnique, https://doi.org/10.1680/jgeot.23.00201

This paper presents results from geotechnical centrifuge tests of tunnelling in dry dense sand beneath loaded non-displacement piles, focusing on the effect of a pile cap (representative also of a raft or grade beam) in contact with the soil surface... Read More about Load transfer mechanisms for capped and uncapped non-displacement piles above tunnels: a centrifuge modelling study.

Can participation in IMF programs facilitate sovereign debt rescheduling? The role of program size (2024)
Journal Article
Bai, Y., Banerji, S., Wang, Z., & Zhang, W. (2024). Can participation in IMF programs facilitate sovereign debt rescheduling? The role of program size. Journal of International Money and Finance, 144, Article 103079. https://doi.org/10.1016/j.jimonfin.2024.103079

We develop a theoretical model to explain the possible inverted U-shaped relationship between IMF loan size and the probability of sovereign debt rescheduling. Given that the IMF is a de facto senior creditor, borrowing too much from the IMF leaves a... Read More about Can participation in IMF programs facilitate sovereign debt rescheduling? The role of program size.

Evaluation of digital musicianship in higher education through playing and creating digital scores (2024)
Conference Proceeding
Moroz, S., Vear, C., & Poltronieri, F. (2024). Evaluation of digital musicianship in higher education through playing and creating digital scores. In Tenor Zurich 2024 (18-28)

This paper presents an evaluation of digital musicianship with digital scores. Primary data was gathered during the DigiScore “Roadshow”of North American universities’ music departments in 2023 and an extended research workshop in Avellino, Italy, 20... Read More about Evaluation of digital musicianship in higher education through playing and creating digital scores.

‘Alright my lovely’: The use of terms of endearment as a mitigation device in the care of people living with dementia in the acute hospital environment (2024)
Journal Article
Bridgstock, L., Pilnick, A., Goldberg, S., & Harwood, R. H. (2024). ‘Alright my lovely’: The use of terms of endearment as a mitigation device in the care of people living with dementia in the acute hospital environment. Health: An Interdisciplinary Journal for the Social Study of Health, Illness and Medicine, https://doi.org/10.1177/13634593241238856

This paper examines how terms of endearment (ToE) are used as a mitigation device in interactions between staff and people living with dementia (PLWD) in the acute hospital environment. ToE are often discouraged in training for healthcare staff. Howe... Read More about ‘Alright my lovely’: The use of terms of endearment as a mitigation device in the care of people living with dementia in the acute hospital environment.

Large Scoping Reviews: Managing volume and potential chaos in a pool of evidence sources (2024)
Journal Article
Alexander, L., Cooper, K., Peters, M. D., Tricco, A. C., Khalil, H., Evans, C., …Pollock, D. (2024). Large Scoping Reviews: Managing volume and potential chaos in a pool of evidence sources. Journal of Clinical Epidemiology, 170, Article 111343. https://doi.org/10.1016/j.jclinepi.2024.111343

Scoping reviews can identify a large number of evidence sources. This commentary describes and provides guidance on planning, conducting, and reporting large scoping reviews. This guidance is informed by experts in scoping review methodology, incl... Read More about Large Scoping Reviews: Managing volume and potential chaos in a pool of evidence sources.

Beyond Acetylene: Exploring Solvent Stabilization of Calcium Carbide‐derived Acetylide Intermediates and Their Significance in Small Organic Molecule Synthesis (2024)
Journal Article
Hainer, A. S., Lanterna, A. E., & Scaiano, J. C. (2024). Beyond Acetylene: Exploring Solvent Stabilization of Calcium Carbide‐derived Acetylide Intermediates and Their Significance in Small Organic Molecule Synthesis. ChemistrySelect, 9(14), Article e202400501. https://doi.org/10.1002/slct.202400501

The reaction of calcium carbide with water has been widely used as a source of acetylene for the synthesis of organic molecules. In contrast with this traditional approach, we use the CaC2 reaction under water-starved conditions and show reactions th... Read More about Beyond Acetylene: Exploring Solvent Stabilization of Calcium Carbide‐derived Acetylide Intermediates and Their Significance in Small Organic Molecule Synthesis.

Combining Reinforcement Learning and Tensor Networks, with an Application to Dynamical Large Deviations (2024)
Journal Article
Gillman, E., Rose, D. C., & Garrahan, J. P. (in press). Combining Reinforcement Learning and Tensor Networks, with an Application to Dynamical Large Deviations. Physical Review Letters,

We present a framework to integrate tensor network (TN) methods with reinforcement learning (RL) for solving dynamical optimisation tasks. We consider the RL actor-critic method, a model-free approach for solving RL problems, and introduce TNs as the... Read More about Combining Reinforcement Learning and Tensor Networks, with an Application to Dynamical Large Deviations.

Exploring the role of study abroad in decolonising geography curricula (2024)
Journal Article
Clare, N., & Keenan, L. (in press). Exploring the role of study abroad in decolonising geography curricula. Journal of Geography in Higher Education, https://doi.org/10.1080/03098265.2024.2338118

Studying abroad has the potential to contribute to wider processes of curriculum decolonisation. More often than not, however, it can actually serve to recolonise and reproduce multiscalar forms of privilege, with the majority of programs seeing stud... Read More about Exploring the role of study abroad in decolonising geography curricula.

Trx4, a novel thioredoxin protein, is important for Toxoplasma gondii fitness (2024)
Journal Article
Zhang, Z., Wang, M., Sun, L., Elsheikha, H. M., Lei, C., Wang, J., …Li, T. (2024). Trx4, a novel thioredoxin protein, is important for Toxoplasma gondii fitness. Parasites and Vectors, 17(1), Article 178. https://doi.org/10.1186/s13071-024-06259-9

Background To successfully replicate within the host cell, Toxoplasma gondii employs several mechanisms to overcome the host cell defenses and mitigate the harmful effects of the free radicals resulting from its own metabolic processes using effector... Read More about Trx4, a novel thioredoxin protein, is important for Toxoplasma gondii fitness.

The Cool Farm Biodiversity metric: an evidence-based online tool to report and improve management of biodiversity at farm scale (2024)
Journal Article
Crowther, L. P., Luke, S. H., Arellano, E. C., McCormack, C. G., Ferreira, V., Hillier, J., …Dicks, L. V. (2024). The Cool Farm Biodiversity metric: an evidence-based online tool to report and improve management of biodiversity at farm scale. Ecological Indicators, 161, Article 111897

Halting biodiversity loss and achieving food security are both aims of the United Nations 2030 Agenda for Sustainable Development, but there is complex interplay between them. Agriculture drives biodiversity loss, but biodiversity provides benefits t... Read More about The Cool Farm Biodiversity metric: an evidence-based online tool to report and improve management of biodiversity at farm scale.

Tort Liability and Unawareness (2024)
Journal Article
Chakravarty, S., Kelsey, D., & Teitelbaum, J. C. (in press). Tort Liability and Unawareness. International Economic Review, https://doi.org/10.1111/iere.12706

We explore the implications of unawareness for tort law. We study cases where injurers and victims initially are unaware that some acts can yield harmful consequences, or that some acts or harmful consequences are even possible, but later become awar... Read More about Tort Liability and Unawareness.

Ultra-high surface area ionic-liquid-derived carbons that meet both gravimetric and volumetric methane storage targets (2024)
Journal Article
Albeladi, N., Blankenship, L. S., & Mokaya, R. (2024). Ultra-high surface area ionic-liquid-derived carbons that meet both gravimetric and volumetric methane storage targets. Energy and Environmental Science, https://doi.org/10.1039/d3ee03957a

The storage of methane, to enable vehicular use, may be achieved in porous solids, but to date, there is no material that meets the gravimetric and volumetric targets (for example those set by the US Department of Energy, DOE) for such use. Here, in... Read More about Ultra-high surface area ionic-liquid-derived carbons that meet both gravimetric and volumetric methane storage targets.

Exploring Reconvictions and 'Crime-Free' Gaps Over Time: What Were the Experience of One Cohort of English Probationers? (2024)
Journal Article
Farrall, S. (in press). Exploring Reconvictions and 'Crime-Free' Gaps Over Time: What Were the Experience of One Cohort of English Probationers?. Criminology and Criminal Justice,

Many, but not all, reconviction studies are undertaken over relatively short periods of time (such as two or five years) and are usually used to gauge the impact of various disposals against one another. This study, based on one cohort of probationer... Read More about Exploring Reconvictions and 'Crime-Free' Gaps Over Time: What Were the Experience of One Cohort of English Probationers?.

A public health approach to modern slavery in the United Kingdom: A co-developed framework (2024)
Journal Article
Such, E., Campos-Matos, I., Hayes, K., Smith, A., Thornton, S., & Woodward, J. (in press). A public health approach to modern slavery in the United Kingdom: A co-developed framework. Public Health,

Objectives Modern slavery is a public health challenge. The objective of this research was to build and refine public health approach to addressing it. Study design A participatory qualitative study with a proof-of-concept exercise. Methods... Read More about A public health approach to modern slavery in the United Kingdom: A co-developed framework.

Inferring interpretable dynamical generators of local quantum observables from projective measurements through machine learning (2024)
Journal Article
Cemin, G., Carnazza, F., Andergassen, S., Martius, G., Carollo, F., & Lesanovsky, I. (2024). Inferring interpretable dynamical generators of local quantum observables from projective measurements through machine learning. Physical Review Applied, 21(4), Article L041001. https://doi.org/10.1103/physrevapplied.21.l041001

To characterize the dynamical behavior of many-body quantum systems, one is usually interested in the evolution of so-called order parameters rather than in characterizing the full quantum state. In many situations, these quantities coincide with the... Read More about Inferring interpretable dynamical generators of local quantum observables from projective measurements through machine learning.

Mental health workers’ perspectives on the implementation of a peer support intervention in five countries: qualitative findings from the UPSIDES study (2024)
Journal Article
Haun, M., Girit, S., Goldfarb, Y., Kalha, J., Korde, P., Kwebiiha, E., …Krumm, S. (in press). Mental health workers’ perspectives on the implementation of a peer support intervention in five countries: qualitative findings from the UPSIDES study. BMJ Open,

Objective: The introduction of peer support in mental health teams creates opportunities and challenges for both peer and non-peer staff. However, the majority of research on mental health workers (MHWs) experiences with peer support comes from high-... Read More about Mental health workers’ perspectives on the implementation of a peer support intervention in five countries: qualitative findings from the UPSIDES study.

A novel prediction model for integrated district energy system based on secondary decomposition and artificial rabbits optimization (2024)
Journal Article
Guo, Y., Tang, Q., Darkwa, J., Duan, X., Su, W., Jia, M., & Mu, J. (2024). A novel prediction model for integrated district energy system based on secondary decomposition and artificial rabbits optimization. Energy and Buildings, 310, Article 114106. https://doi.org/10.1016/j.enbuild.2024.114106

Energy predictions for buildings are the basis for energy efficiency and the implementation of smart technologies to cope with operational and energy planning issues in buildings, playing a crucial role in the implementation of environmental protecti... Read More about A novel prediction model for integrated district energy system based on secondary decomposition and artificial rabbits optimization.