Skip to main content

Research Repository

Advanced Search

All Outputs (4386)

Water soluble, multifunctional antibody-porphyrin gold nanoparticles for targeted photodynamic therapy (2017)
Journal Article
Penon, O., Marín, M. J., Russell, D. A., & Pérez-García, L. (2017). Water soluble, multifunctional antibody-porphyrin gold nanoparticles for targeted photodynamic therapy. Journal of Colloid and Interface Science, 496, https://doi.org/10.1016/j.jcis.2017.02.006

Photodynamic therapy (PDT) is a treatment of cancer by which tumour cells are destroyed using reactive oxygen species produced by photosensitizers following activation with visible or near infrared light. Successful PDT depends on the solubility and... Read More about Water soluble, multifunctional antibody-porphyrin gold nanoparticles for targeted photodynamic therapy.

Manipulating and probing the polarisation of a methyl tunnelling system by field-cycling NMR (2017)
Journal Article
Zhang, B., Abu-Khumra, S., Aibout, A., & Horsewill, A. J. (2017). Manipulating and probing the polarisation of a methyl tunnelling system by field-cycling NMR. Journal of Chemical Physics, 146(6), Article 064302. https://doi.org/10.1063/1.4975173

In NMR the polarisation of the Zeeman system may be routinely probed and manipulated by applying resonant rf pulses. As with spin-½ nuclei, at low temperature the quantum tunnelling states of a methyl rotor are characterised by two energy levels and... Read More about Manipulating and probing the polarisation of a methyl tunnelling system by field-cycling NMR.

Tool selection and the ventral?dorsal organization of tool?related knowledge (2017)
Journal Article
Tobia, M. J., & Madan, C. R. (2017). Tool selection and the ventral?dorsal organization of tool?related knowledge. Physiological Reports, 5(3), Article e13078. https://doi.org/10.14814/phy2.13078

Tool selection is a cognitive process necessary for tool use, and may rely on distinct knowledge under different conditions. This fMRI experiment was designed to identify neural substrates mediating tool selection under different conditions. Particip... Read More about Tool selection and the ventral?dorsal organization of tool?related knowledge.

Measurement of internal surfaces of additively manufactured parts by X-ray computed tomography (2017)
Conference Proceeding
Thompson, A., Körner, L., Senin, N., Lawes, S., Maskery, I., & Leach, R. K. (2017). Measurement of internal surfaces of additively manufactured parts by X-ray computed tomography.

Recent advances in X-ray computed tomography (XCT) have allowed for measurement resolutions approaching the point where XCT can be used for measuring surface topography. These advances make XCT appealing for measuring hard-to-reach or internal surfac... Read More about Measurement of internal surfaces of additively manufactured parts by X-ray computed tomography.

On tilt and curvature dependent errors and the calibration of coherence scanning interferometry (2017)
Journal Article
Su, R., Wang, Y., Coupland, J., & Leach, R. K. (in press). On tilt and curvature dependent errors and the calibration of coherence scanning interferometry. Optics Express, 25(4), https://doi.org/10.1364/OE.25.003297

Although coherence scanning interferometry (CSI) is capable of measuring surface topography with sub-nanometre precision, it is well known that the performance of measuring instruments depends strongly on the local tilt and curvature of the sample su... Read More about On tilt and curvature dependent errors and the calibration of coherence scanning interferometry.

Power, ethics, and person-centred care: using ethnography to examine the everyday practices of unregistered dementia care staff (2017)
Journal Article
Scales, K., Bailey, S., & Schneider, J. M. (2017). Power, ethics, and person-centred care: using ethnography to examine the everyday practices of unregistered dementia care staff. Sociology of Health and Illness, 39(2), 227-243. https://doi.org/10.1111/1467-9566.12524

The social positioning and treatment of persons with dementia reflects dominant biomedical discourses of progressive and inevitable loss of insight, capacity, and personality. Proponents of person-centred care, by contrast, suggest that such loss can... Read More about Power, ethics, and person-centred care: using ethnography to examine the everyday practices of unregistered dementia care staff.

X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3 (2017)
Journal Article
Olcese, C., Patel, M. P., Shoemark, A., Kiviluoto, S., Legendre, M., Williams, H. J., …Mitchison, H. M. (in press). X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3. Nature Communications, 8, Article 14279. https://doi.org/10.1038/ncomms14279

By moving essential body fluids and molecules, motile cilia and flagella govern respiratory mucociliary clearance, laterality determination and the transport of gametes and cerebrospinal fluid. Primary ciliary dyskinesia (PCD) is an autosomal recessi... Read More about X-linked primary ciliary dyskinesia due to mutations in the cytoplasmic axonemal dynein assembly factor PIH1D3.

In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification (2017)
Journal Article
O'Connor, M., Bishop, K., Workman, R. G., Maddison, B. C., & Gough, K. C. (in press). In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification. Prion, 11(1), 54-64. https://doi.org/10.1080/19336896.2016.1259051

The in vitro amplification of prions by serial protein misfolding cyclic amplification has been shown to detect PrPSc to levels at least as sensitive as rodent bioassay but in a fraction of the time. Bovine spongiform encephalopathy is a zoonotic pri... Read More about In vitro amplification of H-type atypical bovine spongiform encephalopathy by protein misfolding cyclic amplification.

Multimodel uncertainty changes in simulated river flows induced by human impact parameterizations (2017)
Journal Article
Liu, X., Tang, Q., Cui, H., Mu, M., Gerten, D., Gosling, S. N., …Wada, Y. (2017). Multimodel uncertainty changes in simulated river flows induced by human impact parameterizations. Environmental Research Letters, 12(2), Article 025009. https://doi.org/10.1088/1748-9326/aa5a3a

Human impacts increasingly affect the global hydrological cycle and indeed dominate hydrological changes in some regions. Hydrologists have sought to identify the human-impact-induced hydrological variations via parameterizing anthropogenic water use... Read More about Multimodel uncertainty changes in simulated river flows induced by human impact parameterizations.

GaitKeeper: a system for measuring canine gait (2017)
Journal Article
Ladha, C., O’Sullivan, J., Belshaw, Z., & Asher, L. (2017). GaitKeeper: a system for measuring canine gait. Sensors, 17(2), https://doi.org/10.3390/s17020309

It is understood gait has the potential to be used as a window into neurodegenerative disorders, identify markers of subclinical pathology, inform diagnostic algorithms of disease progression and measure the efficacy of interventions. Dogs’ gaits are... Read More about GaitKeeper: a system for measuring canine gait.

Volatile organic compounds sensing with use of fibre optic sensor with long period grating and mesoporous nano-scale coating (2017)
Journal Article
Hromadka, J., Korposh, S., Partridge, M., James, S., Davis, F., Charlton, A., …Tatam, R. (2017). Volatile organic compounds sensing with use of fibre optic sensor with long period grating and mesoporous nano-scale coating. Sensors, 17(2), Article 205. https://doi.org/10.3390/s17020205

A long period grating (LPG) modified with a mesoporous film infused with a calixarene as a functional compound was employed for the detection of individual volatile organic compounds (VOCs) and their mixtures. The mesoporous film consisted of an inor... Read More about Volatile organic compounds sensing with use of fibre optic sensor with long period grating and mesoporous nano-scale coating.

Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome (2017)
Journal Article
Das, A., Haque, M., Chikhani, M., Cole, O., Wang, W., Hardman, J. G., & Bates, D. G. (2017). Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome. BMC Pulmonary Medicine, 17(34), https://doi.org/10.1186/s12890-017-0369-7

Background: Clinical trials have, so far, failed to establish clear beneficial outcomes of recruitment maneuvers (RMs) on patient mortality in acute respiratory distress syndrome (ARDS), and the effects of RMs on the cardiovascular system remain poor... Read More about Hemodynamic effects of lung recruitment maneuvers in acute respiratory distress syndrome.

"The will's there and the skill's there": prison mental health care (2017)
Book Chapter
Jordan, M. (2017). "The will's there and the skill's there": prison mental health care. In H. Middleton, & M. Jordan (Eds.), Mental health uncertainty and inevitability: rejuvenating the relationship between social science and psychiatry (105-136). Palgrave Macmillan. https://doi.org/10.1007/978-3-319-43970-9

This discussion explores some of the data from a social science PhD whose fieldwork took place in a category B, adult male, local and remand prison in England run by Her Majesty’s Prison Service (HMPS). The debate analyses National Health Service (NH... Read More about "The will's there and the skill's there": prison mental health care.

Financial social innovation to engage the economically marginalized: insights from an Indian case study (2017)
Journal Article
Bhatt, P., & Ahmad, A. J. (2017). Financial social innovation to engage the economically marginalized: insights from an Indian case study. Entrepreneurship and Regional Development, 29(5-6), 391-413. https://doi.org/10.1080/08985626.2017.1287961

© 2017 Informa UK Limited, trading as Taylor & Francis Group. New sources of finance within the label of ‘impact investing’ have emerged as mechanisms to promote entrepreneurship within marginalized communities. Different vehicles for impact invest... Read More about Financial social innovation to engage the economically marginalized: insights from an Indian case study.

When time is money: sideline jobs, ancillary income and legislative effort (2017)
Journal Article
Hurka, S., Obholzer, L., & Daniel, W. T. (2018). When time is money: sideline jobs, ancillary income and legislative effort. Journal of European Public Policy, 25(5), 651-669. https://doi.org/10.1080/13501763.2017.1285341

Moonlighting, the pursuit of (paid or unpaid) sideline jobs by democratically elected politicians, regularly evokes public outcry. This study provides an empirical test of the claim that moonlighting goes hand-in-hand with a lower degree of parliamen... Read More about When time is money: sideline jobs, ancillary income and legislative effort.

Lessons from Lysenko (2017)
Book Chapter
Marks, J. (2017). Lessons from Lysenko. In W. deJong-Lambert, & N. Krementsov (Eds.), The Lysenko Controversy As A Global Phenomenon - Volume 2 (185-206). Palgrave MacMillan. https://doi.org/10.1007/978-3-319-39179-3_7

This chapter explores the question of whether we can still “learn lessons” from Lysenkoism. Contemporary allusions are often narrowly polemical, usually making the claim that scientific work is being marginalised for non-scientific reasons. However,... Read More about Lessons from Lysenko.

Multi-objective optimisation in inventory planning with supplier selection (2017)
Journal Article
Turk, S., Özcan, E., & John, R. (2017). Multi-objective optimisation in inventory planning with supplier selection. Expert Systems with Applications, 78, https://doi.org/10.1016/j.eswa.2017.02.014

Supplier selection and inventory planning are critical and challenging tasks in Supply Chain Management. There are many studies on both topics and many solution techniques have been proposed dealing with each problem separately. In this study, we pre... Read More about Multi-objective optimisation in inventory planning with supplier selection.

Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline (2017)
Journal Article
John, C., Soler Artigas, M., Hui, J., Nielsen, S. F., Rafaels, N., Paré, P. D., …Tobin, M. D. (2017). Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline. Thorax, 72(5), https://doi.org/10.1136/thoraxjnl-2016-208448

Background: Genome-wide association studies have identified numerous genetic regions that influence cross-sectional lung function. Longitudinal decline in lung function also includes a heritable component but the genetic determinants have yet to be d... Read More about Genetic variants affecting cross-sectional lung function in adults show little or no effect on longitudinal lung function decline.

Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer (2017)
Journal Article
Shafiee, M. N., Mongan, N. P., Seedhouse, C., Chapman, C., Deen, S., Abu, J., & Atiomo, W. (2017). Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer. Acta Obstetricia et Gynecologica Scandinavica, 96(5), 556-562. https://doi.org/10.1111/aogs.13106

Introduction: Women with polycystic ovary syndrome (PCOS) have a 3-fold higher risk of endometrial cancer (EC). Insulin resistance and hyperlipidaemia may be pertinent factors in the pathogenesis of both conditions. The aim of this study was to inves... Read More about Sterol regulatory element binding protein-1 (SREBP1) gene expression is similarly increased in polycystic ovary syndrome and endometrial cancer.