All Outputs (91)

Venous thromboembolism in children with cancer – a population-based cohort study (2014)
Journal Article
Walker, A. J., Grainge, M. J., Card, T. R., West, J., Ranta, S., & Ludvigsson, J. F. (2014). Venous thromboembolism in children with cancer – a population-based cohort study. Thrombosis Research, 133(3), https://doi.org/10.1016/j.thromres.2013.12.021

Introduction: Cancer is a known risk factor for venous thromboembolism (VTE) in adults, but population-based data in children are scarce. Materials and methods: We conducted a cohort study utilising linkage of the Clinical Practice Research Datab... Read More about Venous thromboembolism in children with cancer – a population-based cohort study.

Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England (2014)
Journal Article
Walker, A., West, J., Card, T. R., Humes, D., & Grainge, M. J. (2014). Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England. Journal of Thrombosis and Haemostasis, 12(5), https://doi.org/10.1111/jth.12533

BACKGROUND: Patients with colorectal cancer are at high risk of developing venous thromboembolism (VTE), and recent international guidelines have advised extended prophylaxis for some of these patients following surgery or during chemotherapy. Howeve... Read More about Variation in the risk of venous thromboembolism in people with colorectal cancer: a population-based cohort study from England.

Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study (2014)
Journal Article
Kuo, C. F., Grainge, M. J., Mallen, C., Zhang, W., & Doherty, M. (2015). Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study. Annals of the Rheumatic Diseases, 74(4), 661-667. https://doi.org/10.1136/annrheumdis-2013-204463

Objectives: To describe trends in the epidemiology of gout and patterns of urate-lowering treatment (ULT) in the UK general population from 1997 to 2012. Methods: We used the Clinical Practice Research Datalink to estimate the prevalence and incidenc... Read More about Rising burden of gout in the UK but continuing suboptimal management: A nationwide population study.

Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan (2013)
Journal Article
Kuo, C., Grainge, M. J., See, L., Yu, K., Luo, S., Valdes, A. M., …Doherty, M. (2015). Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan. Annals of the Rheumatic Diseases, 74(2), 369-374. https://doi.org/10.1136/annrheumdis-2013-204067

© 2015, BMJ Publishing Group. All rights reserved. Objective: To examine familial aggregation of gout and to estimate the heritability and environmental contributions to gout susceptibility in the general population. Methods: Using data from the Nati... Read More about Familial aggregation of gout and relative genetic and environmental contributions: a nationwide population study in Taiwan.

Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England (2013)
Journal Article
Sultan, A. A., West, J., Tata, L. J., Fleming, K. M., Nelson-Piercy, C., & Grainge, M. J. (2013). Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England. BMJ, 347(7935), Article 11. https://doi.org/10.1136/bmj.f6099

Objective: To examine the potential for preventing venous thromboembolism during and after antepartum hospital admissions in pregnant women. Design: Cohort study using linked primary (Clinical Practice Research Datalink) and secondary (Hospital E... Read More about Risk of first venous thromboembolism in pregnant women in hospital: population based cohort study from England.

REFINE (REducing Falls in In-patieNt Elderly) using bed and bedside chair pressure sensors linked to radio-pagers in acute hospital care: a randomised controlled trial (2013)
Journal Article
Sahota, O., Drummond, A., Kendrick, D., Grainge, M. J., Vass, C., Sach, T., …Avis, M. (2014). REFINE (REducing Falls in In-patieNt Elderly) using bed and bedside chair pressure sensors linked to radio-pagers in acute hospital care: a randomised controlled trial. Age and Ageing, 43(2), 247-253. https://doi.org/10.1093/ageing/aft155

Background: falls in hospitals are a major problem and contribute to substantial healthcare burden. Advances in sensor technology afford innovative approaches to reducing falls in acute hospital care. However, whether these are clinically effective a... Read More about REFINE (REducing Falls in In-patieNt Elderly) using bed and bedside chair pressure sensors linked to radio-pagers in acute hospital care: a randomised controlled trial.

Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy (2013)
Journal Article
Vaz, L. R., Leonardi-Bee, J., Aveyard, P., Cooper, S., Grainge, M., & Coleman, T. (2014). Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy. Nicotine and Tobacco Research, 16(4), 381-389. https://doi.org/10.1093/ntr/ntt156

Introduction: Previous studies have found partners’ smoking status, multiparity, and nicotine dependence to be associated with smoking cessation in pregnancy. However, no studies have investigated influences on cessation among women using nicotine re... Read More about Factors Associated With Smoking Cessation in Early and Late Pregnancy in the Smoking, Nicotine, and Pregnancy Trial: A Trial of Nicotine Replacement Therapy.

The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis (2013)
Journal Article
Sultan, A. A., Tata, L. J., Grainge, M. J., & West, J. (2013). The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis. PLoS ONE, 8(7), Article e70310. https://doi.org/10.1371/journal.pone.0070310

Background: Recent linkage between primary and secondary care data has provided valuable information for studying heath outcomes that may initially present in different health care settings. The aim of this study was therefore, twofold: to use linke... Read More about The incidence of first venous thromboembolism in and around pregnancy using linked primary and secondary care data: a population based cohort study from England and comparative meta-analysis.

Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis (2012)
Journal Article
Horsted, F., West, J., & Grainge, M. J. (2012). Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis. PLoS Medicine, 9(7), Article e1001275. https://doi.org/10.1371/journal.pmed.1001275

Background: People with cancer are known to be at increased risk of venous thromboembolism (VTE), and this risk is believed to vary according to cancer type, stage of disease, and treatment modality. Our purpose was to summarise the existing literatu... Read More about Risk of venous thromboembolism in patients with cancer: a systematic review and meta-analysis.

REFINE (Reducing Falls in In-patient Elderly): a randomised controlled trial (2009)
Journal Article
Vass, C. D., Sahota, O., Drummond, A., Kendrick, D., Gladman, J., Sach, T., …Grainge, M. (2009). REFINE (Reducing Falls in In-patient Elderly): a randomised controlled trial. Trials, 10, Article 83. https://doi.org/10.1186/1745-6215-10-83

Background: Falls in hospitals are common, resulting in injury and anxiety to patients, and large costs to NHS organisations. More than half of all in-patient falls in elderly people in acute care settings occur at the bedside, during transfers or wh... Read More about REFINE (Reducing Falls in In-patient Elderly): a randomised controlled trial.

Final Protocol and Statistical Analysis Plan for the SNAP Trial - a randomised, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy
Other
Coleman, T., Cooper, S., Thornton, J., Britton, J., Lewis, S., Watts, K., …Grainge, M. J. Final Protocol and Statistical Analysis Plan for the SNAP Trial - a randomised, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy

This NIHR HTA-funded smoking, nicotine and pregnancy (SNAP) trial investigated whether or not nicotine replacement therapy (NRT) is effective, cost-effective and safe when used for smoking cessation by pregnant women. We randomised 1050 women who wer... Read More about Final Protocol and Statistical Analysis Plan for the SNAP Trial - a randomised, double-blind, placebo-controlled trial of nicotine replacement therapy in pregnancy.