All Outputs (3831)

Optimal feedback law recovery by gradient-augmented sparse polynomial regression (2021)
Journal Article
Azmi, B., Kalise, D., & Kunisch, K. (2021). Optimal feedback law recovery by gradient-augmented sparse polynomial regression. Journal of Machine Learning Research, 22, 1-32

A sparse regression approach for the computation of high-dimensional optimal feedback laws arising in deterministic nonlinear control is proposed. The approach exploits the control-theoretical link between Hamilton-Jacobi-Bellman PDEs characterizing... Read More about Optimal feedback law recovery by gradient-augmented sparse polynomial regression.

ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma (2021)
Journal Article
Nasir, A., Cardall, A., Othman, R. T., Nicolaou, N., Lourdusamy, A., Linke, F., …Coyle, B. (2021). ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma. Neuro-Oncology Advances, 3(1), https://doi.org/10.1093/noajnl/vdab030

Background: Therapeutic intervention in metastatic medulloblastoma is dependent upon elucidating the underlying metastatic mechanism. We investigated whether an epithelialmesenchymal transition (EMT)-like pathway could drive medulloblastoma metastasi... Read More about ABCB1 inhibition provides a novel therapeutic target to block TWIST1-induced migration in medulloblastoma.

International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function (2021)
Journal Article
Barnes, N. M., Ahern, G. P., Becamel, C., Bockaert, J., Camilleri, M., Chaumont-Dubel, S., …Hoyer, D. (2021). International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function. Pharmacological Reviews, 73(1), 310-520. https://doi.org/10.1124/pr.118.015552

Copyright © 2020 by The American Society for Pharmacology and Experimental Therapeutics. 5-HT receptors expressed throughout the human body are targets for established therapeutics and various drugs in development. Their diversity of structure and fu... Read More about International Union of Basic and Clinical Pharmacology. CX. Classification of Receptors for 5-hydroxytryptamine; Pharmacology and Function.

Meiosis and beyond – understanding the mechanistic and evolutionary processes shaping the germline genome (2021)
Journal Article
Bergero, R., Ellis, P., Haerty, W., Larcombe, L., Macaulay, I., Mehta, T., …Immler, S. (2021). Meiosis and beyond – understanding the mechanistic and evolutionary processes shaping the germline genome. Biological Reviews, 96(3), 822-841. https://doi.org/10.1111/brv.12680

The separation of germ cell populations from the soma is part of the evolutionary transition to multicellularity. Only genetic information present in the germ cells will be inherited by future generations, and any molecular processes affecting the ge... Read More about Meiosis and beyond – understanding the mechanistic and evolutionary processes shaping the germline genome.

Potential of Bioenergy in Rural Ghana (2021)
Journal Article
Nelson, N., Darkwa, J., Calautit, J., Worall, M., Mokaya, R., Adjei, E., …Ahiekpor, J. (2021). Potential of Bioenergy in Rural Ghana. Sustainability, 13(1), Article 381. https://doi.org/10.3390/su13010381

Crop residues are common in rural Ghana due to the predominant role agriculture plays in livelihood activities in these communities. In this paper we investigate the prospects of exploiting agricultural crop residues for rural development in Ghana th... Read More about Potential of Bioenergy in Rural Ghana.

AhaP, A Quorum Quenching Acylase from Psychrobacter sp. M9-54-1 That Attenuates Pseudomonas aeruginosa and Vibrio coralliilyticus Virulence (2021)
Journal Article
Reina, J. C., Romero, M., Salto, R., Cámara, M., & Llamas, I. (2021). AhaP, A Quorum Quenching Acylase from Psychrobacter sp. M9-54-1 That Attenuates Pseudomonas aeruginosa and Vibrio coralliilyticus Virulence. Marine Drugs, 19(1), Article 16. https://doi.org/10.3390/md19010016

Although Psychrobacter strain M9-54-1 had been previously isolated from the microbiota of holothurians and shown to degrade quorum sensing (QS) signal molecules C6 and C10-homoserine lactone (HSL), little was known about the gene responsible for this... Read More about AhaP, A Quorum Quenching Acylase from Psychrobacter sp. M9-54-1 That Attenuates Pseudomonas aeruginosa and Vibrio coralliilyticus Virulence.

Comparison of simple averaging and latent class modeling to estimate the area of land cover in the presence of reference data variability (2021)
Journal Article
Xing, D., Stehman, S. V., Foody, G. M., & Pengra, B. W. (2021). Comparison of simple averaging and latent class modeling to estimate the area of land cover in the presence of reference data variability. Land, 10(1), Article 35. https://doi.org/10.3390/land10010035

© 2021 by the authors. Licensee MDPI, Basel, Switzerland. Estimates of the area or percent area of the land cover classes within a study region are often based on the reference land cover class labels assigned by analysts interpreting satellite image... Read More about Comparison of simple averaging and latent class modeling to estimate the area of land cover in the presence of reference data variability.

Why is school-to-school collaboration important and how can we make it work? (2021)
Book Chapter
Greany, T. (2021). Why is school-to-school collaboration important and how can we make it work?. In Connecting Classrooms: Unlocking a world of potential - Leading the way (25-32). London: British Council

Networks, collaborations and partnerships between schools can take multiple forms and achieve multiple objectives. This can make them hard to make sense of – and even harder to lead and manage. Nevertheless, this chapter argues that policy makers sho... Read More about Why is school-to-school collaboration important and how can we make it work?.

The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis (2021)
Journal Article
Fordham, B., Sugavanam, T., Edwards, K., Stallard, P., Howard, R., Das Nair, R., …Lamb, S. E. (2021). The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis. Psychological Medicine, 51(1), 21-29. https://doi.org/10.1017/s0033291720005292

The majority of psychological treatment research is dedicated to investigating the effectiveness of cognitive behavioural therapy (CBT) across different conditions, population and contexts. We aimed to summarise the current systematic review evidence... Read More about The evidence for cognitive behavioural therapy in any condition, population or context: a meta-review of systematic reviews and panoramic meta-analysis.

Reinforcement Learning approaches to hippocampus-dependent flexible spatial navigation (2021)
Journal Article
Bast, T., Coombes, S., O’Dea, R., & Tessereau, C. (2021). Reinforcement Learning approaches to hippocampus-dependent flexible spatial navigation. Brain and Neuroscience Advances, 5, https://doi.org/10.1177/2398212820975634

Humans and non-human animals show great flexibility in spatial navigation, including the ability to return to specific locations based on as few as one single experience. To study spatial navigation in the laboratory, watermaze tasks, in which rats h... Read More about Reinforcement Learning approaches to hippocampus-dependent flexible spatial navigation.

Machining-induced thermal damage in cortical bone: Necrosis and micro-mechanical integrity (2021)
Journal Article
Robles-Linares, J. A., Axinte, D., Liao, Z., & Gameros, A. (2021). Machining-induced thermal damage in cortical bone: Necrosis and micro-mechanical integrity. Materials and Design, 197, Article 109215. https://doi.org/10.1016/j.matdes.2020.109215

In bone cutting, the tissue is exposed to necrosis due to temperature elevation, which can significantly influence postoperative results in orthopaedic surgeries. This damage is usually revealed through histological analysis to show the necrotic exte... Read More about Machining-induced thermal damage in cortical bone: Necrosis and micro-mechanical integrity.