All Outputs (44606)

Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: Human ex-vivo study (2024)
Journal Article

Introduction: Drotaverine, paracetamol, and peppermint oil are often prescribed for the treatment of gastrointestinal spasm and pain. This study aimed to evaluate the effect of these drugs alone and combined with the well-known antispasmodic hyoscine... Read More about Evaluation of the mechanism of action of paracetamol, drotaverine, and peppermint oil and their effects in combination with hyoscine butylbromide on colonic motility: Human ex-vivo study.

Inorganic Metal Thiocyanates (2024)
Journal Article

Metal thiocyanates were some of the first pseudohalide compounds to be discovered and adopt a diverse range of structures. This review describes the structures, properties, and syntheses of the known binary and ternary metal thiocyanates. It provides... Read More about Inorganic Metal Thiocyanates.

More excitement across the horizon (2024)
Journal Article

An Unruh-DeWitt detector falling radially into a four-dimensional Schwarzschild black hole, coupled linearly to a massless scalar field that has been prepared in the Hartle-Hawking or Unruh state, has recently been shown to exhibit a local extremum i... Read More about More excitement across the horizon.

Quantitative imaging reveals the role of MpARF proteasomal degradation during gemma germination (2024)
Journal Article

The auxin signaling molecule controls a variety of growth and developmental processes in land plants. Auxin regulates gene expression through a nuclear auxin signaling pathway (NAP) consisting of a ubiquitin ligase auxin receptor TIR1/AFB, its Aux/IA... Read More about Quantitative imaging reveals the role of MpARF proteasomal degradation during gemma germination.

A Scoping Review of Stigma Related to Prostate Cancer in Black Men (2024)
Journal Article

Background Prostate cancer (CaP) disproportionately affects 1-in-4 Black men and is a stigmatised disease within their communities. Yet, Black men are underrepresented in CaP research concerning stigma, which necessitates a scoping review to map av... Read More about A Scoping Review of Stigma Related to Prostate Cancer in Black Men.

Applying Critical Discourse Analysis to Cross-Cultural Mental Health Recovery Research: Positive Changes and No Value Judgement (2024)
Working Paper

The purpose of this paper is to demonstrate how Critical Discourse Analysis (CDA) frameworks can be used in cross-cultural mental health recovery research. CDA is a qualitative approach that critically appraises how language contributes to produce an... Read More about Applying Critical Discourse Analysis to Cross-Cultural Mental Health Recovery Research: Positive Changes and No Value Judgement.

Rydberg superatoms: An artificial quantum system for quantum information processing and quantum optics (2024)
Journal Article

Dense atom ensembles with Rydberg excitations display intriguing collective effects mediated by their strong, long-range dipole-dipole interactions. These collective effects, often modeled using Rydberg superatoms, have gained significant attention a... Read More about Rydberg superatoms: An artificial quantum system for quantum information processing and quantum optics.

What has persisted and what has not: A longitudinal study of changes in teachers’ experiences of Project-Based Teaching and Learning through the COVID-19 Pandemic (2024)
Journal Article

In this qualitative interview-based longitudinal study, we follow and share experiences of teachers from four different high schools in the United States that represent different institutional contexts (Urban, Suburban, Rural, Public and Charter) aro... Read More about What has persisted and what has not: A longitudinal study of changes in teachers’ experiences of Project-Based Teaching and Learning through the COVID-19 Pandemic.

Access to personalised dementia care planning in primary care: a mixed methods evaluation of the PriDem intervention (2024)
Journal Article

Objectives: Provision of personalised care planning is a national priority for people with dementia. Research suggests a lack of quality and consistency of care plans and reviews. The PriDem model of care was developed to deliver feasible and accepta... Read More about Access to personalised dementia care planning in primary care: a mixed methods evaluation of the PriDem intervention.

Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice (2024)
Journal Article

Background: Acne vulgaris (acne) is a common skin condition sometimes needing topical or oral antibiotic treatment. Pharmacists and pharmacy technicians (together known as pharmacy professionals) working in general practice are well placed to ensure... Read More about Pilot and quantitative evaluation of the TARGET acne toolkit by UK pharmacy professionals working in general practice.

ZIF-67 grown onto three-dimensional biomass cotton fibers for efficient adsorption of tetracycline (2024)
Journal Article

In recent years, Metal-Organic Frameworks (MOFs) have garnered significant attention for their potential in tetracycline (TC) removal. However, pure MOFs typically exist in powdered form and tend to aggregate in water, which greatly limits practical... Read More about ZIF-67 grown onto three-dimensional biomass cotton fibers for efficient adsorption of tetracycline.

Trans and Non-Binary Person-Centred Therapists Experiences of, and Responses to, Transprejudice from Clients: A Reflexive Thematic Analysis (2024)
Journal Article

Aims. This qualitative study aims to explore what it is like for trans and non-binary (TNB) person-centred therapists to be exposed to transprejudice in their client work, and how they navigate such relationships. In so doing, the study aims to ampli... Read More about Trans and Non-Binary Person-Centred Therapists Experiences of, and Responses to, Transprejudice from Clients: A Reflexive Thematic Analysis.

The effectiveness of digital interventions for self-management of chronic pain in employment settings: a systematic review. (2024)
Journal Article

Introduction Chronic pain affects over a quarter of the workforce with high economic burden for individuals, employers, and healthcare services. Access to work-related advice for people with chronic pain is variable. This systematic review aims to... Read More about The effectiveness of digital interventions for self-management of chronic pain in employment settings: a systematic review..

Real-time Bayesian Inversion in Resin Transfer Moulding using Neural Surrogates (2024)
Journal Article

In Resin Transfer Moulding (RTM), local variations in reinforcement properties (porosity and permeabil-ity) and the formation of gaps along the reinforcement edges result in non-uniform resin flow patterns, which may cause defects in the produced com... Read More about Real-time Bayesian Inversion in Resin Transfer Moulding using Neural Surrogates.

Impact of patient demographics on treatment outcomes in AML: a population-based registry in England, 2013-2020 (2024)
Journal Article

We report 1- and 5-year survival following AML diagnosis and early mortality, within 30 days of systemic anti-cancer therapy (SACT) treatments, using national cancer registry data in England. Patients aged 18-99 years diagnosed between 2013 and 2... Read More about Impact of patient demographics on treatment outcomes in AML: a population-based registry in England, 2013-2020.

Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension (2024)
Journal Article

Herein, a series of novel arylpiperazine (piperidine) derivatives were designed, synthesized, and evaluated for mechanisms of action through in vitro and in vivo studies. The most promising compound, II-13 (later named as MT-1207), is a potent α1 and... Read More about Discovery of MT-1207: A Novel, Potent Multitarget Inhibitor as a Promising Clinical Candidate for the Treatment of Hypertension.

Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance (2024)
Journal Article

Domestic combustion emissions pose a growing risk to public health, especially in the UK. Existing responses are polarised, with government advocating use of lower emission fuels and stoves while clean air campaigners call for blanket bans on burning... Read More about Reconceiving Domestic Burning Controls: Air Quality Alerts, Behavioural Responsive Regulation, and Designing for Compliance.

Redox Materials for Electrochemical Capacitors (2024)
Journal Article

Researching the everyday educational lives of low-income families: the importance of researcher and participant contexts (2024)
Journal Article

This paper highlights the importance of considering both researcher and participant contexts when exploring everyday educational lives. It emerges during a period of increasing and sustained social inequality in England, and against a backdrop of inc... Read More about Researching the everyday educational lives of low-income families: the importance of researcher and participant contexts.

Life cycle assessment of pavement construction: A case study (2024)
Journal Article

Road construction is often associated with carbon emissions from direct and indirect sources, primarily due to construction and maintenance activities. Currently, there is a lack of comprehensive Life Cycle Assessment (LCA) benchmarks to evaluate fle... Read More about Life cycle assessment of pavement construction: A case study.