All Outputs (3)

Potential nutraceutical properties of leaves from several commonly cultivated plants (2020)
Journal Article
Amat-ur-Rasool, H., Symes, F., Tooth, D., Schaffert, L., Elmorsy, E., Ahmed, M., …Carter, W. G. (2020). Potential nutraceutical properties of leaves from several commonly cultivated plants. Biomolecules, 10(11), 1-22. https://doi.org/10.3390/biom10111556

Chronic dietary ingestion of suitable phytochemicals may assist with limiting or negating neurodegenerative decline. Current therapeutics used to treat Alzheimer disease elicit broad adverse drug reactions, and alternative sources of cholinesterase i... Read More about Potential nutraceutical properties of leaves from several commonly cultivated plants.

Carbamazepine induces a bioenergetics disruption to microvascular endothelial cells from the blood-brain barrier (2020)
Journal Article
Alelwani, W., Elmorsy, E., Kattan, S. W., Babteen, N. A., Alnajeebi, A. M., Al-Ghafari, A., & Carter, W. G. (2020). Carbamazepine induces a bioenergetics disruption to microvascular endothelial cells from the blood-brain barrier. Toxicology Letters, 333, 184-191. https://doi.org/10.1016/j.toxlet.2020.08.006

Carbamazepine (CBZ) is a widely employed anti-seizure medication that crosses the blood-brain barrier (BBB) to exert its anti-convulsant action. The effects of CBZ on components of the BBB have yet to be completely delineated. Hence the current study... Read More about Carbamazepine induces a bioenergetics disruption to microvascular endothelial cells from the blood-brain barrier.

Do Post-Translational Modifications Influence Protein Aggregation in Neurodegenerative Diseases: A Systematic Review (2020)
Journal Article
Schaffert, L., & Carter, W. G. (2020). Do Post-Translational Modifications Influence Protein Aggregation in Neurodegenerative Diseases: A Systematic Review. Brain Sciences, 10(4), https://doi.org/10.3390/brainsci10040232

The accumulation of abnormal protein aggregates represents a universal hallmark of neurodegenerative diseases (NDDs). Post-translational modifications (PTMs) regulate protein structure and function. Dysregulated PTMs may influence the propensity for... Read More about Do Post-Translational Modifications Influence Protein Aggregation in Neurodegenerative Diseases: A Systematic Review.